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Home / Equine Research Bank / J Clin Microbiol / Evidence for two serotype G3 subtypes among equine rotavirus...
Journal of clinical microbiology1992; 30(2); 485-491; doi: 10.1128/jcm.30.2.485-491.1992

Evidence for two serotype G3 subtypes among equine rotaviruses.

Abstract: Ten cultivable equine rotavirus isolates, two of North American, six of British, and two of Irish origin, were compared with standard rotavirus strains and with each other by cross neutralization, neutralization with a panel of monoclonal antibodies (MAbs), hybridization to a simian rotavirus (SA-11) VP7 gene probe, and reaction with rotavirus subgrouping and serotyping MAbs in enzyme-linked immunosorbent assays. Six isolates, two of which had previously been serotyped as G3 by other workers, were found to be serotype G3; one was confirmed to be G5, and three were not related to serotypes G1 to G10. The serotype G3 strains were divisible into two subtypes, G3A and G3B, on the basis of cross neutralization. This division was also apparent in reactions with neutralizing VP7-specific MAbs and in the liquid hybridization assay. Two of the isolates were not bound by either subgroup MAb, six were bound by both subgroup I and II MAbs, and two were bound by only the subgroup I MAb. The assays used in this characterization provide a range of epidemiological information for use in future field investigations.
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Publication Date: 1992-02-01 PubMed ID: 1371520PubMed Central: PMC265082DOI: 10.1128/jcm.30.2.485-491.1992Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research focused on studying differences among ten isolates of equine rotavirus from North America, Britain and Ireland, using tests such as cross neutralization and hybridization assays. Their findings suggest there may be two subtypes of serotype G3 in equine rotaviruses, named G3A and G3B, which could have potential significance in field investigations and addressing equine rotavirus epidemiology.

Initiation of the study

  • The study began with the collection and culture of ten isolable equine rotavirus samples from different regions: two from North America, six from Britain, and two from Ireland.
  • These samples were compared with established rotavirus strains and each other using a number of assays.

Methods used in the study

  • A range of tests was performed to classify and compare the virus samples, including cross neutralization (to see how the viruses react to antibodies), hybridization to a simian rotavirus (SA-11) VP7 gene probe (to compare genetic similarities), and the use of enzyme-linked immunosorbent assays with serotyping and subgrouping monoclonal antibodies (to determine the rotavirus subgroup).

Key findings and interpretation

  • Out of the 10 isolates, six were found to be of serotype G3, one was confirmed to be G5, and three did not relate to serotypes G1 to G10.
  • The G3 strains were further differentiated into two subtypes, G3A and G3B, using cross neutralization.
  • The existence of two subtypes was confirmed by reactions with neutralizing VP7-specific monoclonal antibodies and in a liquid hybridization assay.

Subgroup Binding Differences

  • Two of the isolates could not bind with either subgroup monoclonal antibody, six bound with both subgroup I and II monoclonal antibodies, and two bound with only the subgroup I monoclonal antibody.

Implications of the findings

  • These tests for characterizing rotaviruses provide valuable epidemiological information, adding to the understanding of equine rotavirus diversity.
  • The findings towards the existence of two subtypes within serotype G3 could direct future field investigations and help in understanding the disease epidemiology and devising more effective control strategies.

Cite This Article

APA
Browning GF, Chalmers RM, Fitzgerald TA, Snodgrass DR. (1992). Evidence for two serotype G3 subtypes among equine rotaviruses. J Clin Microbiol, 30(2), 485-491. https://doi.org/10.1128/jcm.30.2.485-491.1992

Publication

Journal of clinical microbiology
ISSN: 0095-1137
NlmUniqueID: 7505564
Country: United States
Language: English
Volume: 30
Issue: 2
Pages: 485-491

Researcher Affiliations

Browning, G F
  • Moredun Research Institute, Edinburgh, Scotland, United Kingdom.
Chalmers, R M
    Fitzgerald, T A
      Snodgrass, D R

        MeSH Terms

        • Animals
        • Antibodies, Monoclonal
        • Antigens, Viral
        • Capsid / immunology
        • Capsid Proteins
        • Enzyme-Linked Immunosorbent Assay
        • Epidemiologic Methods
        • Epitopes
        • Horse Diseases / epidemiology
        • Horse Diseases / microbiology
        • Horses
        • Neutralization Tests
        • Rotavirus / classification
        • Rotavirus / immunology
        • Rotavirus / isolation & purification
        • Rotavirus Infections / epidemiology
        • Rotavirus Infections / microbiology
        • Rotavirus Infections / veterinary
        • Serotyping

        References

        This article includes 52 references
        1. Thouless ME. Rotavirus polypeptides.. J Gen Virol 1979 Jul;44(1):187-97.
          pubmed: 227989doi: 10.1099/0022-1317-44-1-187google scholar: lookup
        2. Ahmed MU, Taniguchi K, Kobayashi N, Urasawa T, Wakasugi F, Islam M, Shaikh H, Urasawa S. Characterization by enzyme-linked immunosorbent assay using subgroup- and serotype-specific monoclonal antibodies of human rotavirus obtained from diarrheic patients in Bangladesh.. J Clin Microbiol 1989 Jul;27(7):1678-81.
          pubmed: 2549093doi: 10.1128/jcm.27.7.1678-1681.1989google scholar: lookup
        3. Browning GF, Chalmers RM, Fitzgerald TA, Snodgrass DR. Serological and genomic characterization of L338, a novel equine group A rotavirus G serotype.. J Gen Virol 1991 May;72 ( Pt 5):1059-64.
          pubmed: 1851806doi: 10.1099/0022-1317-72-5-1059google scholar: lookup
        4. Snodgrass DR, Fitzgerald T, Campbell I, Scott FM, Browning GF, Miller DL, Herring AJ, Greenberg HB. Rotavirus serotypes 6 and 10 predominate in cattle.. J Clin Microbiol 1990 Mar;28(3):504-7.
          pubmed: 2157736doi: 10.1128/jcm.28.3.504-507.1990google scholar: lookup
        5. Padilla-Noriega L, Arias CF, López S, Puerto F, Snodgrass DR, Taniguchi K, Greenberg HB. Diversity of rotavirus serotypes in Mexican infants with gastroenteritis.. J Clin Microbiol 1990 Jun;28(6):1114-9.
          pubmed: 2166073doi: 10.1128/jcm.28.6.1114-1119.1990google scholar: lookup
        6. Ohta C, Hoshi A, Goto H, Tsunoda N, Tagami M, Akita H. Epizootiological and virological studies of foal diarrhea associated with serotype 3 rotavirus.. Nihon Juigaku Zasshi 1990 Oct;52(5):1049-56.
          pubmed: 2177800doi: 10.1292/jvms1939.52.1049google scholar: lookup
        7. Shaw RD, Vo PT, Offit PA, Coulson BS, Greenberg HB. Antigenic mapping of the surface proteins of rhesus rotavirus.. Virology 1986 Dec;155(2):434-51.
          pubmed: 2431540doi: 10.1016/0042-6822(86)90205-9google scholar: lookup
        8. Coulson BS. Variation in neutralization epitopes of human rotaviruses in relation to genomic RNA polymorphism.. Virology 1987 Aug;159(2):209-16.
          pubmed: 2441519doi: 10.1016/0042-6822(87)90457-0google scholar: lookup
        9. Mackow ER, Shaw RD, Matsui SM, Vo PT, Benfield DA, Greenberg HB. Characterization of homotypic and heterotypic VP7 neutralization sites of rhesus rotavirus.. Virology 1988 Aug;165(2):511-7.
          pubmed: 2457279doi: 10.1016/0042-6822(88)90595-8google scholar: lookup
        10. Flores J, Green KY, Garcia D, Sears J, Perez-Schael I, Avendaño LF, Rodriguez WB, Taniguchi K, Urasawa S, Kapikian AZ. Dot hybridization assay for distinction of rotavirus serotypes.. J Clin Microbiol 1989 Jan;27(1):29-34.
          pubmed: 2536391doi: 10.1128/jcm.27.1.29-34.1989google scholar: lookup
        11. Urasawa S, Urasawa T, Taniguchi K, Wakasugi F, Kobayashi N, Chiba S, Sakurada N, Morita M, Morita O, Tokieda M. Survey of human rotavirus serotypes in different locales in Japan by enzyme-linked immunosorbent assay with monoclonal antibodies.. J Infect Dis 1989 Jul;160(1):44-51.
          pubmed: 2543711doi: 10.1093/infdis/160.1.44google scholar: lookup
        12. Bellinzoni RC, Blackhall JO, Mattion NM, Estes MK, Snodgrass DR, LaTorre JL, Scodeller EA. Serological characterization of bovine rotaviruses isolated from dairy and beef herds in Argentina.. J Clin Microbiol 1989 Nov;27(11):2619-23.
          pubmed: 2553769doi: 10.1128/jcm.27.11.2619-2623.1989google scholar: lookup
        13. Coulson BS, Fowler KJ, Bishop RF, Cotton RG. Neutralizing monoclonal antibodies to human rotavirus and indications of antigenic drift among strains from neonates.. J Virol 1985 Apr;54(1):14-20.
          pubmed: 2579249doi: 10.1128/JVI.54.1.14-20.1985google scholar: lookup
        14. Gerna G, Sarasini A, di Matteo A, Parea M, Orsolini P, Battaglia M. Identification of two subtypes of serotype 4 human rotavirus by using VP7-specific neutralizing monoclonal antibodies.. J Clin Microbiol 1988 Jul;26(7):1388-92.
          pubmed: 2842373doi: 10.1128/jcm.26.7.1388-1392.1988google scholar: lookup
        15. Matsuno S, Hasegawa A, Mukoyama A, Inouye S. A candidate for a new serotype of human rotavirus.. J Virol 1985 May;54(2):623-4.
          pubmed: 2985825doi: 10.1128/JVI.54.2.623-624.1985google scholar: lookup
        16. Offit PA, Blavat G. Identification of the two rotavirus genes determining neutralization specificities.. J Virol 1986 Jan;57(1):376-8.
          pubmed: 3001359doi: 10.1128/JVI.57.1.376-378.1986google scholar: lookup
        17. Hoshino Y, Saif LJ, Sereno MM, Chanock RM, Kapikian AZ. Infection immunity of piglets to either VP3 or VP7 outer capsid protein confers resistance to challenge with a virulent rotavirus bearing the corresponding antigen.. J Virol 1988 Mar;62(3):744-8.
          pubmed: 2828669doi: 10.1128/JVI.62.3.744-748.1988google scholar: lookup
        18. Ruiz AM, López IV, López S, Espejo RT, Arias CF. Molecular and antigenic characterization of porcine rotavirus YM, a possible new rotavirus serotype.. J Virol 1988 Nov;62(11):4331-6.
          pubmed: 2845146doi: 10.1128/JVI.62.11.4331-4336.1988google scholar: lookup
        19. Shaw RD, Stoner-Ma DL, Estes MK, Greenberg HB. Specific enzyme-linked immunoassay for rotavirus serotypes 1 and 3.. J Clin Microbiol 1985 Aug;22(2):286-91.
          pubmed: 2993354doi: 10.1128/jcm.22.2.286-291.1985google scholar: lookup
        20. Hoshino Y, Sereno MM, Midthun K, Flores J, Kapikian AZ, Chanock RM. Independent segregation of two antigenic specificities (VP3 and VP7) involved in neutralization of rotavirus infectivity.. Proc Natl Acad Sci U S A 1985 Dec;82(24):8701-4.
          pubmed: 3001716doi: 10.1073/pnas.82.24.8701google scholar: lookup
        21. Offit PA, Clark HF, Blavat G, Greenberg HB. Reassortant rotaviruses containing structural proteins vp3 and vp7 from different parents induce antibodies protective against each parental serotype.. J Virol 1986 Nov;60(2):491-6.
          pubmed: 3021983doi: 10.1128/JVI.60.2.491-496.1986google scholar: lookup
        22. Coulson BS, Unicomb LE, Pitson GA, Bishop RF. Simple and specific enzyme immunoassay using monoclonal antibodies for serotyping human rotaviruses.. J Clin Microbiol 1987 Mar;25(3):509-15.
          pubmed: 3033013doi: 10.1128/jcm.25.3.509-515.1987google scholar: lookup
        23. Beards GM, Desselberger U, Flewett TH. Temporal and geographical distributions of human rotavirus serotypes, 1983 to 1988.. J Clin Microbiol 1989 Dec;27(12):2827-33.
          pubmed: 2556435doi: 10.1128/jcm.27.12.2827-2833.1989google scholar: lookup
        24. Gunn PR, Sato F, Powell KF, Bellamy AR, Napier JR, Harding DR, Hancock WS, Siegman LJ, Both GW. Rotavirus neutralizing protein VP7: antigenic determinants investigated by sequence analysis and peptide synthesis.. J Virol 1985 Jun;54(3):791-7.
          pubmed: 2582147doi: 10.1128/JVI.54.3.791-797.1985google scholar: lookup
        25. Sonza S, Breschkin AM, Holmes IH. The major surface glycoprotein of simian rotavirus (SA11) contains distinct epitopes.. Virology 1984 Apr 30;134(2):318-27.
          pubmed: 6085822doi: 10.1016/0042-6822(84)90300-3google scholar: lookup
        26. Herring AJ, Inglis NF, Ojeh CK, Snodgrass DR, Menzies JD. Rapid diagnosis of rotavirus infection by direct detection of viral nucleic acid in silver-stained polyacrylamide gels.. J Clin Microbiol 1982 Sep;16(3):473-7.
          pubmed: 6182158doi: 10.1128/jcm.16.3.473-477.1982google scholar: lookup
        27. Hoshino Y, Wyatt RG, Greenberg HB, Flores J, Kapikian AZ. Serotypic similarity and diversity of rotaviruses of mammalian and avian origin as studied by plaque-reduction neutralization.. J Infect Dis 1984 May;149(5):694-702.
          pubmed: 6202807doi: 10.1093/infdis/149.5.694google scholar: lookup
        28. Greenberg HB, Valdesuso J, van Wyke K, Midthun K, Walsh M, McAuliffe V, Wyatt RG, Kalica AR, Flores J, Hoshino Y. Production and preliminary characterization of monoclonal antibodies directed at two surface proteins of rhesus rotavirus.. J Virol 1983 Aug;47(2):267-75.
          pubmed: 6312065doi: 10.1128/JVI.47.2.267-275.1983google scholar: lookup
        29. Gillespie J, Kalica A, Conner M, Schiff E, Barr M, Holmes D, Frey M. The isolation, propagation and characterization of tissue-cultured equine rotaviruses.. Vet Microbiol 1984 Feb;9(1):1-14.
          pubmed: 6326375doi: 10.1016/0378-1135(84)90074-9google scholar: lookup
        30. ARCHETTI I, HORSFALL FL Jr. Persistent antigenic variation of influenza A viruses after incomplete neutralization in ovo with heterologous immune serum.. J Exp Med 1950 Nov 1;92(5):441-62.
          pubmed: 14778924doi: 10.1084/jem.92.5.441google scholar: lookup
        31. Albert MJ, Unicomb LE, Tzipori SR, Bishop RF. Isolation and serotyping of animal rotaviruses and antigenic comparison with human rotaviruses. Brief report.. Arch Virol 1987;93(1-2):123-30.
          pubmed: 3028338doi: 10.1007/BF01313898google scholar: lookup
        32. Midthun K, Flores J, Taniguchi K, Urasawa S, Kapikian AZ, Chanock RM. Genetic relatedness among human rotavirus genes coding for VP7, a major neutralization protein, and its application to serotype identification.. J Clin Microbiol 1987 Jul;25(7):1269-74.
          pubmed: 3038948doi: 10.1128/jcm.25.7.1269-1274.1987google scholar: lookup
        33. Greenberg H, McAuliffe V, Valdesuso J, Wyatt R, Flores J, Kalica A, Hoshino Y, Singh N. Serological analysis of the subgroup protein of rotavirus, using monoclonal antibodies.. Infect Immun 1983 Jan;39(1):91-9.
          pubmed: 6185436doi: 10.1128/iai.39.1.91-99.1983google scholar: lookup
        34. Hoshino Y, Wyatt RG, Greenberg HB, Kalica AR, Flores J, Kapikian AZ. Isolation, propagation, and characterization of a second equine rotavirus serotype.. Infect Immun 1983 Sep;41(3):1031-7.
          pubmed: 6309657doi: 10.1128/iai.41.3.1031-1037.1983google scholar: lookup
        35. Hoshino Y, Wyatt RG, Greenberg HB, Kalica AR, Flores J, Kapikian AZ. Isolation and characterization of an equine rotavirus.. J Clin Microbiol 1983 Sep;18(3):585-91.
          pubmed: 6313746doi: 10.1128/jcm.18.3.585-591.1983google scholar: lookup
        36. Browning GF, Chalmers RM, Fitzgerald TA, Corley KT, Campbell I, Snodgrass DR. Rotavirus serotype G3 predominates in horses.. J Clin Microbiol 1992 Jan;30(1):59-62.
          pubmed: 1310333doi: 10.1128/jcm.30.1.59-62.1992google scholar: lookup
        37. Hardy ME, Woode GN, Xu ZC, Williams JD, Conner ME, Dwyer RM, Powell DG. Analysis of serotypes and electropherotypes of equine rotaviruses isolated in the United States.. J Clin Microbiol 1991 May;29(5):889-93.
          pubmed: 1647407doi: 10.1128/jcm.29.5.889-893.1991google scholar: lookup
        38. Browning GF, Fitzgerald TA, Chalmers RM, Snodgrass DR. A novel group A rotavirus G serotype: serological and genomic characterization of equine isolate FI23.. J Clin Microbiol 1991 Sep;29(9):2043-6.
          pubmed: 1663521doi: 10.1128/jcm.29.9.2043-2046.1991google scholar: lookup
        39. Fitzgerald TA, Browning GF. Increased sensitivity of a rotavirus serotyping enzyme-linked immunosorbent assay by the incorporation of CaCl2.. J Virol Methods 1991 Aug;33(3):299-304.
          pubmed: 1664432doi: 10.1016/0166-0934(91)90029-ygoogle scholar: lookup
        40. Gouvea V, Glass RI, Woods P, Taniguchi K, Clark HF, Forrester B, Fang ZY. Polymerase chain reaction amplification and typing of rotavirus nucleic acid from stool specimens.. J Clin Microbiol 1990 Feb;28(2):276-82.
          pubmed: 2155916doi: 10.1128/jcm.28.2.276-282.1990google scholar: lookup
        41. Gerna G, Sarasini A, Arista S, di Matteo A, Giovannelli L, Parea M, Halonen P. Prevalence of human rotavirus serotypes in some European countries 1981-1988.. Scand J Infect Dis 1990;22(1):5-10.
          pubmed: 2157276doi: 10.3109/00365549009023112google scholar: lookup
        42. Flores J, Sears J, Schael IP, White L, Garcia D, Lanata C, Kapikian AZ. Identification of human rotavirus serotype by hybridization to polymerase chain reaction-generated probes derived from a hyperdivergent region of the gene encoding outer capsid protein VP7.. J Virol 1990 Aug;64(8):4021-4.
          pubmed: 2164610doi: 10.1128/JVI.64.8.4021-4024.1990google scholar: lookup
        43. Taniguchi K, Urasawa T, Kobayashi N, Gorziglia M, Urasawa S. Nucleotide sequence of VP4 and VP7 genes of human rotaviruses with subgroup I specificity and long RNA pattern: implication for new G serotype specificity.. J Virol 1990 Nov;64(11):5640-4.
          pubmed: 2170690doi: 10.1128/JVI.64.11.5640-5644.1990google scholar: lookup
        44. Larralde G, Flores J. Identification of gene 4 alleles among human rotaviruses by polymerase chain reaction-derived probes.. Virology 1990 Nov;179(1):469-73.
          pubmed: 2171217doi: 10.1016/0042-6822(90)90317-kgoogle scholar: lookup
        45. Dyall-Smith ML, Lazdins I, Tregear GW, Holmes IH. Location of the major antigenic sites involved in rotavirus serotype-specific neutralization.. Proc Natl Acad Sci U S A 1986 May;83(10):3465-8.
          pubmed: 2422651doi: 10.1073/pnas.83.10.3465google scholar: lookup
        46. Hoshino Y, Gorziglia M, Valdesuso J, Askaa J, Glass RI, Kapikian AZ. An equine rotavirus (FI-14 strain) which bears both subgroup I and subgroup II specificities on its VP6.. Virology 1987 Apr;157(2):488-96.
          pubmed: 2435059doi: 10.1016/0042-6822(87)90291-1google scholar: lookup
        47. Clark HF, Hoshino Y, Bell LM, Groff J, Hess G, Bachman P, Offit PA. Rotavirus isolate WI61 representing a presumptive new human serotype.. J Clin Microbiol 1987 Sep;25(9):1757-62.
          pubmed: 2443534doi: 10.1128/jcm.25.9.1757-1762.1987google scholar: lookup
        48. Taniguchi K, Hoshino Y, Nishikawa K, Green KY, Maloy WL, Morita Y, Urasawa S, Kapikian AZ, Chanock RM, Gorziglia M. Cross-reactive and serotype-specific neutralization epitopes on VP7 of human rotavirus: nucleotide sequence analysis of antigenic mutants selected with monoclonal antibodies.. J Virol 1988 Jun;62(6):1870-4.
          pubmed: 2452893doi: 10.1128/JVI.62.6.1870-1874.1988google scholar: lookup
        49. Nishikawa K, Hoshino Y, Taniguchi K, Green KY, Greenberg HB, Kapikian AZ, Chanock RM, Gorziglia M. Rotavirus VP7 neutralization epitopes of serotype 3 strains.. Virology 1989 Aug;171(2):503-15.
          pubmed: 2474892doi: 10.1016/0042-6822(89)90620-xgoogle scholar: lookup
        50. Unicomb LE, Coulson BS, Bishop RF. Experience with an enzyme immunoassay for serotyping human group A rotaviruses.. J Clin Microbiol 1989 Mar;27(3):586-8.
          pubmed: 2541171doi: 10.1128/jcm.27.3.586-588.1989google scholar: lookup
        51. Nagesha HS, Brown LE, Holmes IH. Neutralizing monoclonal antibodies against three serotypes of porcine rotavirus.. J Virol 1989 Aug;63(8):3545-9.
          pubmed: 2545925doi: 10.1128/JVI.63.8.3545-3549.1989google scholar: lookup
        52. Browning GF, Chalmers RM, Snodgrass DR, Batt RM, Hart CA, Ormarod SE, Leadon D, Stoneham SJ, Rossdale PD. The prevalence of enteric pathogens in diarrhoeic thoroughbred foals in Britain and Ireland.. Equine Vet J 1991 Nov;23(6):405-9.
          pubmed: 1663866doi: 10.1111/j.2042-3306.1991.tb03751.xgoogle scholar: lookup

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        1. Nemoto M, Matsumura T. Equine rotavirus infection.. J Equine Sci 2021 Mar;32(1):1-9.
          doi: 10.1294/jes.32.1pubmed: 33776534google scholar: lookup
        2. Matthijnssens J, Ons E, De Coster S, Conceição-Neto N, Gryspeerdt A, Van Ranst M, Raue R. Molecular characterization of equine rotaviruses isolated in Europe in 2013: implications for vaccination.. Vet Microbiol 2015 Mar 23;176(1-2):179-85.
          doi: 10.1016/j.vetmic.2015.01.011pubmed: 25637313google scholar: lookup
        3. Bailey KE, Gilkerson JR, Browning GF. Equine rotaviruses--current understanding and continuing challenges.. Vet Microbiol 2013 Nov 29;167(1-2):135-44.
          doi: 10.1016/j.vetmic.2013.07.010pubmed: 23932076google scholar: lookup
        4. Nemoto M, Tsunemitsu H, Murase H, Nambo Y, Sato S, Orita Y, Imagawa H, Bannai H, Tsujimura K, Yamanaka T, Matsumura T, Kondo T. Antibody response in vaccinated pregnant mares to recent G3BP[12] and G14P[12] equine rotaviruses.. Acta Vet Scand 2012 Nov 6;54(1):63.
          doi: 10.1186/1751-0147-54-63pubmed: 23130609google scholar: lookup
        5. Collins PJ, Cullinane A, Martella V, O'Shea H. Molecular characterization of equine rotavirus in Ireland.. J Clin Microbiol 2008 Oct;46(10):3346-54.
          doi: 10.1128/JCM.00995-08pubmed: 18716232google scholar: lookup
        6. Martella V, Pratelli A, Greco G, Gentile M, Fiorente P, Tempesta M, Buonavoglia C. Nucleotide sequence variation of the VP7 gene of two G3-type rotaviruses isolated from dogs.. Virus Res 2001 Apr;74(1-2):17-25.
          doi: 10.1016/s0168-1702(00)00230-6pubmed: 11226570google scholar: lookup
        7. Ciarlet M, I a P, Conner ME, Liprandi F. Antigenic and molecular analyses reveal that the equine rotavirus strain H-1 is closely related to porcine, but not equine, rotaviruses: interspecies transmission from pigs to horses?. Virus Genes 2001 Jan;22(1):5-20.
          doi: 10.1023/a:1008175716816pubmed: 11210939google scholar: lookup
        8. Isa P, Wood AR, Netherwood T, Ciarlet M, Imagawa H, Snodgrass DR. Survey of equine rotaviruses shows conservation of one P genotype in background of two G genotypes.. Arch Virol 1996;141(9):1601-12.
          doi: 10.1007/BF01718285pubmed: 8893784google scholar: lookup
        9. Browning GF, Begg AP. Prevalence of G and P serotypes among equine rotaviruses in the faeces of diarrhoeic foals.. Arch Virol 1996;141(6):1077-89.
          doi: 10.1007/BF01718611pubmed: 8712925google scholar: lookup
        10. Imagawa H, Tanaka T, Sekiguchi K, Fukunaga Y, Anzai T, Minamoto N, Kamada M. Electropherotypes, serotypes, and subgroups of equine rotaviruses isolated in Japan.. Arch Virol 1993;131(1-2):169-76.
          doi: 10.1007/BF01379088pubmed: 8392320google scholar: lookup
        11. Dwyer RM. Rotaviral diarrhea.. Vet Clin North Am Equine Pract 1993 Aug;9(2):311-9.
          doi: 10.1016/s0749-0739(17)30398-xpubmed: 8358646google scholar: lookup
        12. Imagawa H, Ishida S, Uesugi S, Masanobu K, Fukunaga Y, Nakagomi O. Genetic analysis of equine rotavirus by RNA-RNA hybridization.. J Clin Microbiol 1994 Aug;32(8):2009-12.
          doi: 10.1128/jcm.32.8.2009-2012.1994pubmed: 7989559google scholar: lookup
        13. Ciarlet M, Reggeti F, Piña CI, Liprandi F. Equine rotaviruses with G14 serotype specificity circulate among venezuelan horses.. J Clin Microbiol 1994 Oct;32(10):2609-12.
          doi: 10.1128/jcm.32.10.2609-2612.1994pubmed: 7814511google scholar: lookup
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