Ex vivo evaluation of 7 polydioxanone for closure of equine ventral midline celiotomies.
Abstract: The objective of this study was to compare the bursting strength (BS) and mode of failure (MF) of ventral midline (VM) celiotomies closed with USP 7 polydioxanone (7PD) in 1 or 2 simple continuous sections. A bursting strength model, consisting of inserting and inflating a 200-L polyurethane bladder through a 25-cm VM celiotomy, was used on 15 fresh equine cadavers. Celiotomies were closed using 7PD in 2 separate sections (4 knots), 2 continuous sections (3 knots), or a single section (2 knots) using a simple continuous pattern. The horses' signalment, body weight, number of total knots, MF, and BS were recorded and analyzed statistically for interactions. No difference was found between the BS of VM celiotomies closure types (P = 0.4). All celiotomy/ suture constructs failed at the abdominal wall. The celiotomy closure types evaluated in this study provided a secure method of closure in VM celiotomies in vivo. L’objectif de la présente étude était de comparer la force d’éclatement (BS) et le mode d’échec (MF) de laparotomies par la ligne ventrale médiale (VM) refermées avec du 7 polydioxanone USP (7PD) en une ou 2 sections continues. Un modèle de force d’éclatement, consistant en l’insertion et le gonflement une vessie de 200 L en polyuréthane via une laparotomie de 25 cm fut utilisé sur 15 cadavres frais de cheval. Les laparotomies étaient refermées en utilisant le 7PD en deux sections séparées (4 nœuds), 2 sections continues (3 nœuds), ou une section simple (2 nœuds) au moyen d’un patron simple continu. L’historique des chevaux, leur poids corporel, le nombre total de nœuds, MF, et BS ont été enregistrés et analysés statistiquement pour les interactions. Aucune différence ne fut trouvée entre les BS et les types de fermetures de VM des laparotomies ( = 0,4). Toutes les laparotomies/modes de suture ont lâché au niveau de la paroi abdominale. Les types de fermeture des laparotomies évalués dans ce projet ont fourni une méthode sécuritaire de fermeture par la VM de laparotomies .(Traduit par Docteur Serge Messier).
Publication Date: 2014-04-02 PubMed ID: 24688180PubMed Central: PMC3962281
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- Journal Article
Summary
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This study explores the effectiveness of USP 7 polydioxanone (7PD) in the closure of ventral midline (VM) celiotomies in horses. The researchers found no difference in the strength and mode of failure of the sutures irrespective of whether they were applied in one or two simple, continuous sections.
Study Objective and Methods
- This study aimed at testing the effectiveness of 7 polydioxanone (7PD), a suture material, for the closure of surgical openings made in the abdominal wall of horses, more particularly in the midline ventral (VM) section. The focus was to assess two core mechanical properties: bursting strength (BS) and mode of failure (MF).
- For this experiment, a bursting strength model was designed. This involved inserting and inflating a large (200-L) polyurethane bladder into a 25-cm VM surgical opening created in 15 fresh equine cadavers. The surgical opening, or celiotomy, was closed with 7PD sutures applied in different ways: two separate sections (four knots), two continuous sections (three knots), or a single section (two knots).
Data Collection and Analysis
- Various data points were collected including the horses’ specifics (signalment), body weight, total number of knots used in the suture, mode of suture or celiotomy failure (MF), and bursting strength (BS).
- These data were statistically analyzed to identify any potential interactions or patterns. The type of suture did not significantly impact either the strength or the manner in which the sutures failed. All sutures failed at the level of the abdominal wall, irrespective of their types or the number of sections they consisted of.
Findings and Conclusion
- The analysis revealed that there was no statistically significant difference between the bursting strengths of different suture types (P = 0.4), indicating that the suture strength remained consistent irrespective of the technique used for the closure of VM celiotomies.
- All celiotomy/suture constructs failed at the abdominal wall and this failure was common for all types of suturing techniques used.
- Overall, the study found that all techniques evaluated provided a reliable method of closure for midline ventral celiotomies in horses.
Cite This Article
APA
Anderson SL, Bracamonte JL, Hendrick S.
(2014).
Ex vivo evaluation of 7 polydioxanone for closure of equine ventral midline celiotomies.
Can J Vet Res, 78(2), 156-160.
Publication
Researcher Affiliations
- Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
- Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
- Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
MeSH Terms
- Animals
- Female
- Horses / surgery
- Laparoscopy / methods
- Laparoscopy / veterinary
- Male
- Polydioxanone / pharmacology
- Random Allocation
- Sutures / standards
- Sutures / veterinary
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This article includes 16 references
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Citations
This article has been cited 2 times.- Scharner D, Gittel C, Winter K, Blaue D, Schedlbauer C, Vervuert I, Brehm W. Comparison of incisional complications between skin closures using a simple continuous or intradermal pattern: a pilot study in horses undergoing ventral median celiotomy.. PeerJ 2018;6:e5772.
- Souza CRS, Farnsworth KD, Ragle CA. Comparison of incisional bursting strength of 2-strand continuous crossing and simple continuous patterns for closure of the equine linea alba.. Can Vet J 2018 Feb;59(2):171-173.
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