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Home / Equine Research Bank / Foods / Exploring Potential Bioactive Peptides in Fermented Bactrian...
Foods (Basel, Switzerland)2020; 9(12); 1817; doi: 10.3390/foods9121817

Exploring Potential Bioactive Peptides in Fermented Bactrian Camel’s Milk and Mare’s Milk Made by Mongolian Nomads.

Abstract: To date, bioactive proteins and peptides from minor livestock milks and their fermented products have been scarcely reported. In Mongolia, nomads are commonly rearing five livestock animal species (i.e., cow, camel, goat, horse, and sheep) for milking and other purposes. In this study, we analyzed the peptide composition in fermented milks of Bactrian camels () and horses, produced by Mongolian nomads for self-consumption. Peptides from skimmed fermented milks were separated by ultrafiltration and reverse-phase high-performance liquid chromatography. Then, their amino acid sequences were determined by matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry. Consequently, eleven peptides were identified in the fermented camel's milk including four from β-casein (β-CN), three from α-CN, and two from both κ-CN and lactophorin. On the other hand, twenty-four peptides were identified in the fermented mare's milk including nineteen from β-CN, three from α-CN, and one from both κ-CN and α-CN. According to previous reports on the bioactivities of milk-derived peptides, antibacterial and antihypertensive activities were promising in both the fermented camel's milk and mare's milk. In addition, potential antioxidant activity was conjectured in the fermented camel's milk. Further investigations are currently needed to clarify the potential role of immunomodulatory peptides in the two fermented milks.
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Publication Date: 2020-12-07 PubMed ID: 33297514PubMed Central: PMC7762409DOI: 10.3390/foods9121817Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study investigates the bioactive peptides found in fermented camel and horse milk produced by Mongolian nomads. The research identifies specific peptides and discusses their potential for beneficial activity, such as being antibacterial, antihypertensive, and possibly antioxidant.

Methodology

  • The scientists analyzed the peptide composition in fermented milks of Bactrian camels and horses, produced by Mongolian nomads for self-consumption.
  • They used skimmed fermented milks and separated peptides through ultrafiltration and reverse-phase high-performance liquid chromatography, which is a method designed to separate, identify, and quantify each component in a mixture.
  • The amino acid sequences of these peptides were determined by matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry—a sophisticated analytical technique that allows precise, fast identification and quantification of compounds.

Findings

  • In the fermented camel’s milk, eleven peptides were identified including four from β-casein (β-CN), three from α-CN, and two from both κ-CN and lactophorin.
  • Twenty-four peptides were identified in the fermented mare’s milk including nineteen from β-CN, three from α-CN, and one from both κ-CN and α-CN.
  • Caseins (β-CN, α-CN, κ-CN) represent the main proteins present in milk, so their peptide composition plays an important role in the overall biological activity of milk.

Potential Bioactivities

  • The research infers the potential bioactivities of these peptides based on previous reports on the bioactivities of milk-derived peptides.
  • Both the fermented camel’s milk and mare’s milk showed promise for antibacterial and antihypertensive activities.
  • Antioxidant activity was also suggested in the fermented camel’s milk, which could help reduce inflammation and combat oxidative stress.

Further Investigations

  • The authors suggest that more investigations are required to clarify the potential role of immunomodulatory peptides in the two fermented milks.
  • Immunomodulatory peptides could help strengthen the immune system and support the body’s resistance against disease.

Cite This Article

APA
Ganzorig K, Urashima T, Fukuda K. (2020). Exploring Potential Bioactive Peptides in Fermented Bactrian Camel’s Milk and Mare’s Milk Made by Mongolian Nomads. Foods, 9(12), 1817. https://doi.org/10.3390/foods9121817

Publication

Foods (Basel, Switzerland)
ISSN: 2304-8158
NlmUniqueID: 101670569
Country: Switzerland
Language: English
Volume: 9
Issue: 12
PII: 1817

Researcher Affiliations

Ganzorig, Khuukhenbaatar
  • Department of Animal and Food Hygiene, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Nishi, Inada-Cho, Obihiro, Hokkaido 080-8555, Japan.
Urashima, Tadasu
  • Department of Life and Food Sciences, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Nishi, Inada-Cho, Obihiro, Hokkaido 080-8555, Japan.
Fukuda, Kenji
  • Department of Agriculture and Animal Science, Research Center for Global Agromedicine, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Nishi, Inada-Cho, Obihiro, Hokkaido 080-8555, Japan.

Conflict of Interest Statement

The authors declare no conflict of interest.

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Citations

This article has been cited 8 times.
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