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Veterinaria italiana2018; 54(2); 155-159; doi: 10.12834/VetIt.1032.5496.2

Exuberant granulation tissue in a horse: successful treatment by the intralesional injection of 4% formaldehyde solution.

Abstract: The healing of wounds located on the equine distal limbs can often be impaired, which can result in exuberant granulation tissue and its associated aesthetic alteration and functional failures. Although a number of therapies have been developed and assessed, the treatment of these wounds still presents challenges. This report describes the treatment of exuberant granulation tissue in a horse using an intra-lesional injection of 4% formaldehyde solution. The successful outcome of this treatment suggests that further investigations are required in order to better evaluate its efficacy, as well as the incidence and the severity of any adverse reaction.
Publication Date: 2018-07-19 PubMed ID: 30019331DOI: 10.12834/VetIt.1032.5496.2Google Scholar: Lookup
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Summary

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The researchers have investigated and documented the treatment of excessive wound tissue (exuberant granulation tissue) in a horse’s lower legs using a 4% formaldehyde solution injected directly into the wound. The success of this treatment indicates a need for further research into its efficiency and possible side effects.

Background of the study

  • The authors of this research started by providing insights into the challenges often encountered when dealing with wounds located on the lower limbs of horses. The issue at hand is that such wounds can result in exuberant granulation tissue, which refers to the overgrowth of wound tissue during the healing process. This not only affects the physical appearance of the horse, but can also lead to functional problems.
  • Despite various therapies being available to tackle this issue, the authors pointed out that treating such wounds still presents significant challenges.

The Treatment and its Outcome

  • In a bid to offer a potential solution to the problem, the researchers treated a horse suffering from exuberant granulation tissue using a 4% formaldehyde solution, which was injected directly into the wound (intralesional injection).
  • The treatment was reported to be successful, thus providing a significant contribution to the existing methods of dealing with such wounds in horses.

Need for Further Investigation

  • While the results of this study are promising, the authors stress the need for further research. In particular, they advocate for more comprehensive investigations that would better evaluate the efficacy of the provided treatment method.
  • Furthermore, it is also important to examine the incidence and severity of any adverse reactions associated with this treatment. This constitutes a crucial part of understanding the complete impact of this potential treatment method.

Cite This Article

APA
Varasano V, Marruchella G, Petrizzi L. (2018). Exuberant granulation tissue in a horse: successful treatment by the intralesional injection of 4% formaldehyde solution. Vet Ital, 54(2), 155-159. https://doi.org/10.12834/VetIt.1032.5496.2

Publication

ISSN: 1828-1427
NlmUniqueID: 0201543
Country: Italy
Language: English
Volume: 54
Issue: 2
Pages: 155-159

Researcher Affiliations

Varasano, Vincenzo
  • University of Teramo, Faculty of Veterinary Medicine, Loc. Piano d'Accio, 64100, Teramo, Italy.
Marruchella, Giuseppe
    Petrizzi, Lucio

      MeSH Terms

      • Animals
      • Female
      • Formaldehyde / administration & dosage
      • Granulation Tissue / drug effects
      • Granulation Tissue / pathology
      • Horses
      • Injections, Intralesional
      • Remission Induction
      • Solutions
      • Wound Healing / drug effects