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Equine veterinary journal1993; 25(2); 147-151; doi: 10.1111/j.2042-3306.1993.tb02926.x

Factors influencing the outcome of equine anaesthesia: a review of 1,314 cases.

Abstract: Patient data, physiological variables and recovery quality were extracted from 1,314 records of equine anaesthetics covering a 7-year period and analysed retrospectively. Better recovery quality was significantly associated with shorter duration of anaesthesia, longer recovery times, less invasive surgery, a lower pulse rate at induction and higher pulse and respiratory rates during anaesthesia. Nineteen animals suffered serious anaesthetic-related problems (1.4% incidence) and 9 died (0.68% incidence). Clinical treatment of hypotension during anaesthesia significantly reduced the hypotensive index but did not significantly alter the recovery quality or incidence of post-anaesthetic myopathy. The severity of the myopathy was, however, markedly reduced in the animals treated for hypotension.
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Publication Date: 1993-03-01 PubMed ID: 8467775DOI: 10.1111/j.2042-3306.1993.tb02926.xGoogle Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research reviews 1,314 cases of equine anaesthetic outcomes over a seven-year span, focusing on patient data, physiological conditions, and recovery quality. Major factors affecting recovery included duration of anaesthesia, surgical invasiveness, and pulse rate. The study also looks at the impact of treatment for hypotension on recovery and post-anaesthetic myopathy.

Scope and Methodology of the Research

  • The study examined 1,314 cases of equine anaesthesia over a seven-year period.
  • The data mined included patient details, physiological measurements, recovery times, surgical invasiveness, and post-anesthesia complications.
  • All these factors were retrospectively analyzed to identify a correlation with recovery quality after anaesthesia.
  • The study also looked specifically at instances of serious anaesthetic-related problems, including death, and conditions like hypotension during anaesthesia and post-anaesthetic myopathy.

Key Findings

  • The research found that the quality of recovery after anaesthesia was significantly associated with factors such as the duration of the anaesthesia (shorter durations led to better recovery), the recovery times (longer times indicated better recovery), less invasive surgeries, lower pulse rate at induction and higher pulse and respiratory rates during anaesthesia.
  • Out of the entire sample, 19 animals encountered serious anaesthetic-related complications (1.4% of cases), and 9 died (0.68% of cases).
  • The treatment of hypotension during anaesthesia effectively reduced the hypotensive index, which means it prevented blood pressure from dropping too low. This, however, did not significantly impact the recovery quality or the incidence of post-anaesthetic myopathy, a muscle condition common after anaesthesia.
  • Interestingly, although the treatment for hypotension didn’t affect the incidence of myopathy, it greatly lessened the severity of the condition in treated animals.

Implications of the Research

  • The findings suggest that certain procedures during equine anaesthesia, such as minimizing the duration, lengthening recovery time and controlling pulse and respiratory rates, can positively influence the recovery quality.
  • A noteworthy point is the effectiveness of treating hypotension during anaesthesia, as it significantly reduces the severity of post-anaesthetic myopathy, although it does not alter its occurrence or overall recovery.
  • The revelation carries significant implications for anaesthesia practices in equine care, as it presents precise areas for intervention to improve equine anaesthesia outcomes.

Cite This Article

APA
Young SS, Taylor PM. (1993). Factors influencing the outcome of equine anaesthesia: a review of 1,314 cases. Equine Vet J, 25(2), 147-151. https://doi.org/10.1111/j.2042-3306.1993.tb02926.x

Publication

Equine veterinary journal
ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 25
Issue: 2
Pages: 147-151

Researcher Affiliations

Young, S S
  • Animal Health Trust, Newmarket, Suffolk, UK.
Taylor, P M

    MeSH Terms

    • Anesthesia / adverse effects
    • Anesthesia / veterinary
    • Animals
    • Female
    • Horses / physiology
    • Male
    • Muscular Diseases / etiology
    • Muscular Diseases / veterinary
    • Pulse
    • Respiration
    • Retrospective Studies
    • Time Factors
    • Treatment Outcome

    Citations

    This article has been cited 34 times.
    1. Murillo C, Weng HY, Weil AB, Kreuzer M, Ko JC. Perioperative Brain Function Monitoring with Electroencephalography in Horses Anesthetized with Multimodal Balanced Anesthetic Protocol Subjected to Surgeries. Animals (Basel) 2022 Oct 20;12(20).
      doi: 10.3390/ani12202851pubmed: 36290236google scholar: lookup
    2. Rabbogliatti V, Amari M, Brioschi FA, Di Cesare F, Zani DD, De Zani D, Di Giancamillo M, Cagnardi P, Ravasio G. Use of dexmedetomidine repeated subcutaneous administration for balanced anaesthesia in horses. BMC Vet Res 2022 Jul 11;18(1):269.
      doi: 10.1186/s12917-022-03350-0pubmed: 35818051google scholar: lookup
    3. Hewitt-Dedman CL, O'Neill HD, Bladon BM. Arthroscopic removal of palmar intermediate carpal bone fracture fragments in four horses using a transthecal approach through the carpal flexor tendon sheath. Vet Surg 2022 Aug;51(6):929-939.
      doi: 10.1111/vsu.13813pubmed: 35403724google scholar: lookup
    4. Pratt S, Barnes TS, Cowling N, de Klerk K, Rainger J, Sole-Guitart A, Woldeyohannes S, Goodwin W. Bias Associated with Peripheral Non-Invasive Compared to Invasive Arterial Blood Pressure Monitoring in Healthy Anaesthetised and Standing Horses Using the Bionet BM7Vet. Vet Sci 2022 Jan 28;9(2).
      doi: 10.3390/vetsci9020052pubmed: 35202305google scholar: lookup
    5. Gozalo-Marcilla M, Bettschart-Wolfensberger R, Johnston M, Taylor PM, Redondo JI. Data Collection for the Fourth Multicentre Confidential Enquiry into Perioperative Equine Fatalities (CEPEF4) Study: New Technology and Preliminary Results. Animals (Basel) 2021 Aug 30;11(9).
      doi: 10.3390/ani11092549pubmed: 34573515google scholar: lookup
    6. Kälin I, Henze IS, Ringer SK, Torgerson PR, Bettschart-Wolfensberger R. Comparison of Recovery Quality Following Medetomidine versus Xylazine Balanced Isoflurane Anaesthesia in Horses: A Retrospective Analysis. Animals (Basel) 2021 Aug 19;11(8).
      doi: 10.3390/ani11082440pubmed: 34438896google scholar: lookup
    7. Cunneen A, Pratt S, Perkins N, McEwen M, Truchetti G, Rainger J, Farry T, Kidd L, Goodwin W. Total Intravenous Anaesthesia with Ketamine, Medetomidine and Midazolam as Part of a Balanced Anaesthesia Technique in Horses Undergoing Castration. Vet Sci 2021 Jul 26;8(8).
      doi: 10.3390/vetsci8080142pubmed: 34437464google scholar: lookup
    8. Vermedal H, Valverde A, Sears W. Effect of anesthesia duration on the quality of recovery in horses undergoing elective and emergency surgeries using the same anesthetic protocol. Can J Vet Res 2021 Jul;85(3):193-200.
      pubmed: 34248263
    9. Gozalo-Marcilla M, Ringer SK. Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature. Animals (Basel) 2021 Jun 14;11(6).
      doi: 10.3390/ani11061777pubmed: 34198637google scholar: lookup
    10. Sabiza S, Naddaf H, Jalali SM, Baniadam A, Mosallanejad B. The effects of doxapram on haematology, serum biochemical parameters and erythrocyte oxidant/ antioxidant status in dogs anaesthetized with propofol. Vet Med Sci 2021 Mar;7(2):586-592.
      doi: 10.1002/vms3.398pubmed: 33210449google scholar: lookup
    11. Gillen A, Mudge M, Caldwell F, Munsterman A, Hanson R, Brawner W, Almond G, Green E, Stephens J, Walz J. Outcome of external beam radiotherapy for treatment of noncutaneous tumors of the head in horses: 32 cases (1999-2015). J Vet Intern Med 2020 Nov;34(6):2808-2816.
      doi: 10.1111/jvim.15954pubmed: 33165966google scholar: lookup
    12. Gough SL, Anderson JDC, Dixon JJ. Computed tomographic cervical myelography in horses: Technique and findings in 51 clinical cases. J Vet Intern Med 2020 Sep;34(5):2142-2151.
      doi: 10.1111/jvim.15848pubmed: 32705729google scholar: lookup
    13. Gómez Fernández L, Niimura Del Barrio MC, Loughran C. Use of adrenaline continuous infusion to treat hypotension during general anaesthesia in a cow and a calf. Ir Vet J 2020;73:13.
      doi: 10.1186/s13620-020-00164-0pubmed: 32637073google scholar: lookup
    14. Laurenza C, Ansart L, Portier K. Risk Factors of Anesthesia-Related Mortality and Morbidity in One Equine Hospital: A Retrospective Study on 1,161 Cases Undergoing Elective or Emergency Surgeries. Front Vet Sci 2019;6:514.
      doi: 10.3389/fvets.2019.00514pubmed: 32039253google scholar: lookup
    15. Tokushige H, Araki M, Kusano K, Arima D, Ito H, Yamazaki Y, Urayama S, Kambayashi Y, Tateno O, Ohta M. A retrospective comparison of induction with thiopental/guaifenesin and propofol/ketamine in Thoroughbred racehorses anesthetized with sevoflurane and medetomidine during arthroscopic surgery. J Equine Sci 2019 Jul;30(2):25-31.
      doi: 10.1294/jes.30.25pubmed: 31285690google scholar: lookup
    16. Tokushige H, Okano A, Arima D, Ito H, Kambayashi Y, Minamijima Y, Ohta M. Clinical effects of constant rate infusions of medetomidine-propofol combined with sevoflurane anesthesia in Thoroughbred racehorses undergoing arthroscopic surgery. Acta Vet Scand 2018 Nov 5;60(1):71.
      doi: 10.1186/s13028-018-0426-0pubmed: 30396363google scholar: lookup
    17. Tokushige H, Kushiro A, Okano A, Maeda T, Ito H, Wakuno A, Nagata SI, Ohta M. Clinical evaluation of constant rate infusion of alfaxalone-medetomidine combined with sevoflurane anesthesia in Thoroughbred racehorses undergoing arthroscopic surgery. Acta Vet Scand 2018 Sep 4;60(1):50.
      doi: 10.1186/s13028-018-0406-4pubmed: 30180855google scholar: lookup
    18. Noel-Morgan J, Muir WW. Anesthesia-Associated Relative Hypovolemia: Mechanisms, Monitoring, and Treatment Considerations. Front Vet Sci 2018;5:53.
      doi: 10.3389/fvets.2018.00053pubmed: 29616230google scholar: lookup
    19. Mirra A, Klopfenstein Bregger MD, Levionnois OL. Suspicion of Postanesthetic Femoral Paralysis of the Non-Dependent Limb in a Horse. Front Vet Sci 2018;5:12.
      doi: 10.3389/fvets.2018.00012pubmed: 29468166google scholar: lookup
    20. Niimura Del Barrio MC, David F, Hughes JML, Clifford D, Wilderjans H, Bennett R. A retrospective report (2003-2013) of the complications associated with the use of a one-man (head and tail) rope recovery system in horses following general anaesthesia. Ir Vet J 2018;71:6.
      doi: 10.1186/s13620-018-0117-1pubmed: 29456834google scholar: lookup
    21. Mizobe F, Wakuno A, Okada J, Otsuka T, Ishikawa Y, Kurimoto S. Clinical usefulness of intravenous constant rate infusion of fentanyl and medetomidine under sevoflurane anesthesia in Thoroughbred racehorses undergoing internal fixation surgery. J Equine Sci 2017;28(4):143-147.
      doi: 10.1294/jes.28.143pubmed: 29270071google scholar: lookup
    22. Scarabelli S, Rioja E. Retrospective evaluation of correlation and agreement between two recovery scoring systems in horses. Vet Rec 2018 Feb 10;182(6):169.
      doi: 10.1136/vr.104546pubmed: 29196490google scholar: lookup
    23. Ninu AR, Saxena AC, Sivanarayanan TB, Remya V, Binsila BK, Maiti SK, Zama MM. Caesarean in mare by Marcenac incision under local anaesthesia. Iran J Vet Res 2015 Winter;16(1):117-9.
      pubmed: 27175164
    24. Umar MA, Fukui S, Kawase K, Itami T, Yamashita K. Cardiovascular effects of total intravenous anesthesia using ketamine-medetomidine-propofol (KMP-TIVA) in horses undergoing surgery. J Vet Med Sci 2015 Mar;77(3):281-8.
      doi: 10.1292/jvms.14-0370pubmed: 25409552google scholar: lookup
    25. Aarnes TK, Bednarski RM, Bertone AL, Hubbell JA, Lerche P. Recovery from desflurane anesthesia in horses with and without post-anesthetic xylazine. Can J Vet Res 2014 Apr;78(2):103-9.
      pubmed: 24688171
    26. Ohta M, Kurimoto S, Ishikawa Y, Tokushige H, Mae N, Nagata S, Mamada M. Cardiovascular effects of dobutamine and phenylephrine infusion in sevoflurane-anesthetized Thoroughbred horses. J Vet Med Sci 2013 Nov;75(11):1443-8.
      doi: 10.1292/jvms.13-0104pubmed: 23832627google scholar: lookup
    27. Rioja E, Cernicchiaro N, Costa MC, Valverde A. Perioperative risk factors for mortality and length of hospitalization in mares with dystocia undergoing general anesthesia: a retrospective study. Can Vet J 2012 May;53(5):502-10.
      pubmed: 23115362
    28. Joseph EJ, Love L, Mayakis M, Varner K. Preanesthetic Administration of Trazodone Does Not Impact Anesthetic Recovery Scores in Horses. Animals (Basel) 2025 Oct 6;15(19).
      doi: 10.3390/ani15192907pubmed: 41096502google scholar: lookup
    29. Román Durá B, Dunham O, Grulke S, Salciccia A, Dupont J, Sandersen C. A Retrospective Study on Pre- and Intraoperative Predictors on the Recovery Quality of Horses After General Anesthesia. Vet Sci 2025 Mar 11;12(3).
      doi: 10.3390/vetsci12030262pubmed: 40266986google scholar: lookup
    30. Lindqvist A, Nyman G, Rydén A, Wattle O. Effect of an adjustable ceiling to prevent premature rising attempts after general anesthesia in healthy ponies and horses: A pilot study. Vet Surg 2025 Jul;54(5):851-859.
      doi: 10.1111/vsu.14181pubmed: 39887480google scholar: lookup
    31. Henderson ARP, Valverde A, Koenig J, Sears W. Effects of anesthetic protocol, procedure, and recovery stall and interval on the quality of recovery in repeatedly anesthetized horses. Can J Vet Res 2025 Jan;89(1):17-25.
      pubmed: 39744466
    32. Brumund L, Wittenberg-Voges L, Rohn K, Kästner SBR. Risk assessment in equine anesthesia: a first evaluation of the usability, utility and predictivity of the two-part CHARIOT. Front Vet Sci 2024;11:1384525.
      doi: 10.3389/fvets.2024.1384525pubmed: 38846780google scholar: lookup
    33. Chang LJ, Weng HY, Lien CY, Chen KS. Retrospective Comparison of the Anesthetic Effects of Tiletamine-Zolazepam with Dexmedetomidine and Ketamine with Dexmedetomidine in Captive Formosan Serow (Capricornis swinhoei). Animals (Basel) 2024 May 8;14(10).
      doi: 10.3390/ani14101413pubmed: 38791631google scholar: lookup
    34. Fesmire CC, Peal B, Ruff J, Moyer E, McParland TJ, Derks K, O'Neil E, Emke C, Johnson B, Ghosh S, Petrella RA, DeWitt MR, Prange T, Fogle C, Sano MB. Investigation of integrated time nanosecond pulse irreversible electroporation against spontaneous equine melanoma. Front Vet Sci 2024;11:1232650.
      doi: 10.3389/fvets.2024.1232650pubmed: 38352036google scholar: lookup
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