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Open veterinary journal2022; 12(6); 830-838; doi: 10.5455/OVJ.2022.v12.i6.7

Features of the clinical picture of keratitis in horses with different forms of the course of the disease.

Abstract: Keratitis is a common cause of eye diseases in horses, often resulting in complete loss of vision. The purpose of this article is to study the features of the clinical picture of primary and secondary keratitis in horses, depending on the form of the course of the disease. The study was conducted in 2019 at 22 private horse breeding farms. The study involved 80 horses with keratitis, which were divided into two equal groups depending on the diagnosis of primary or secondary keratitis. The effectiveness of the therapies was compared 1, 3, and 6 months after the start of treatment. Following a 1-month therapy, only a minority of horses with primary keratitis had their eye functions fully restored, the number of horses with macula was two times higher (p ≤ 0.05), the number of horses with nebula was seven times higher (p ≤ 0.001), and leukomas were reported in most of the cases ( p ≤ 0.0001). The effectiveness of the therapy for keratitis is directly related to the peculiarities of treatment and adherence to the regimen.
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Publication Date: 2022-11-13 PubMed ID: 36650853PubMed Central: PMC9805768DOI: 10.5455/OVJ.2022.v12.i6.7Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article is about a study conducted to understand the clinical features of keratitis, an eye disease in horses and how it differs in primary and secondary instances. The effectiveness of treatments were then examined in consideration with these differing forms.

Objective and Methodology

  • The study intended to investigate the clinical picture of two categories of keratitis (primary and secondary) in horses, and how it varies depending on the disease’s progression.
  • In 2019, the study was conducted at 22 private horse breeding farms involving 80 horses that had keratitis.
  • These horses were divided evenly into two groups based on whether they were diagnosed with primary or secondary keratitis.
  • Treatment effects were monitored and compared at three intervals: one month, three months, and six months following the treatment initiation.

Findings

  • Results displayed that after a month of therapy, only a small proportion of horses with primary keratitis had full restoration of their eye functions.
  • Additionally, the number of horses exhibiting macula (a blemish or small spot within the retina) was double, the instances of nebula (a preprocessing stage of cataract) was seven times higher, and majority reported having leukomas (a form of chronic keratitis producing a white opacity in the cornea). These differences were statistically significant.

Conclusion

  • It can be concluded from the study’s findings that the therapy’s effectiveness for keratitis hinges on specific factors related to treatment and adherence to the regimen.
  • This study underscores the need for improved understanding of the disease’s progression, more precise diagnoses (primary versus secondary), and better treatment strategies customized according to the form of the disease’s progression.

Cite This Article

APA
Lazareva Y, Rayisyan M, Mironova E. (2022). Features of the clinical picture of keratitis in horses with different forms of the course of the disease. Open Vet J, 12(6), 830-838. https://doi.org/10.5455/OVJ.2022.v12.i6.7

Publication

Open veterinary journal
ISSN: 2218-6050
NlmUniqueID: 101653182
Country: Libya
Language: English
Volume: 12
Issue: 6
Pages: 830-838

Researcher Affiliations

Lazareva, Yuliya
  • Department of Biology and General Genetics, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Rayisyan, Maria
  • Department of Regulatory Relations of Circulation of Medicines and Medical Devices, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Mironova, Ekaterina
  • Department of Polyclinic Therapy, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

MeSH Terms

  • Horses
  • Animals
  • Keratitis / diagnosis
  • Keratitis / veterinary
  • Keratitis / complications
  • Horse Diseases / diagnosis

Conflict of Interest Statement

The authors declare that there are no conflicts of interest related to this article.

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