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Veterinary medicine and science2024; 10(4); e1534; doi: 10.1002/vms3.1534

Fetal rhabdomyoma in a Thoroughbred filly.

Abstract: A newborn Thoroughbred filly presented with a large mass located on the ventro-rostral aspect of the mandible. The mass was surgically removed under general anaesthesia. Upon gross examination, the mass was well circumscribed with a heterogeneous lobulated appearance. The results of histopathology and immunohistochemistry were consistent with a diagnosis of congenital fetal rhabdomyoma. On follow-up at six months post-surgical excision, no abnormalities were noted on clinical examination.
Publication Date: 2024-07-08 PubMed ID: 38975617PubMed Central: PMC11228825DOI: 10.1002/vms3.1534Google Scholar: Lookup
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Summary

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The research discusses a unique case of a newborn Thoroughbred filly (female horse) diagnosed with fetal rhabdomyoma—a rare congenital tumor—located on a specific part of the mandible. The tumor was successfully removed through surgery and the horse showed no more signs of abnormalities after six months.

Introduction

  • The researchers presented a case of a newborn Thoroughbred filly that had developed a large, unusual tumor on its lower jaw.
  • This type of tumor, known as fetal rhabdomyoma, is a rare kind of benign tumor that mostly occurs in humans and is even rarer to find in animals.
  • The case is noteworthy as instances of such tumors in horses are extremely uncommon.

Diagnosis

  • The filly presented with the tumor on the ventro-rostral aspect of the mandible, which refers to the lower and forward-facing part of the jaw.
  • The unusual mass was well defined and presented a lobulated (made up of lobes) appearance.
  • Using histopathology, a technique that involves studying changes in tissues caused by diseases, and immunohistochemistry, a method that uses antibodies to detect the presence of specific proteins in tissues, the researchers confirmed the diagnosis of fetal rhabdomyoma.

Treatment

  • The tumor was surgically removed under general anaesthesia, ensuring the least distress and discomfort to the filly.
  • Post surgery, the animal was observed and cared for to check for any abnormalities or signs of relapse.

Outcome

  • Follow-up checks were carried out six months after the surgical excision of the tumor.
  • No abnormalities were observed in the filly, and it showed signs of normal growth and development consistent with young horses of its age.
  • The successful removal of the tumor and the absence of any complications post-surgery indicate a good prognosis for similar cases in the future.

Cite This Article

APA
Rapezzano G, Foote A, Petrini F, Pereira R, Marcatili M. (2024). Fetal rhabdomyoma in a Thoroughbred filly. Vet Med Sci, 10(4), e1534. https://doi.org/10.1002/vms3.1534

Publication

ISSN: 2053-1095
NlmUniqueID: 101678837
Country: England
Language: English
Volume: 10
Issue: 4
Pages: e1534
PII: e1534

Researcher Affiliations

Rapezzano, Giulia
  • Internal medicine and Surgery departments, Pool House Equine Clinic, Fradley, UK.
Foote, Alastair
  • Clinical pathology department, Rossdales Laboratories, Newmarket, UK.
Petrini, Filippo
  • Internal medicine and Surgery departments, Pool House Equine Clinic, Fradley, UK.
Pereira, Regina
  • Internal medicine and Surgery departments, Pool House Equine Clinic, Fradley, UK.
Marcatili, Marco
  • Internal medicine and Surgery departments, Pool House Equine Clinic, Fradley, UK.

MeSH Terms

  • Rhabdomyoma / veterinary
  • Rhabdomyoma / surgery
  • Rhabdomyoma / diagnosis
  • Rhabdomyoma / pathology
  • Rhabdomyoma / diagnostic imaging
  • Animals
  • Horse Diseases / surgery
  • Horse Diseases / diagnosis
  • Horse Diseases / pathology
  • Horse Diseases / congenital
  • Horses
  • Female
  • Animals, Newborn

Grant Funding

  • IVC Evidensia will contribute to the publication costs of the article

Conflict of Interest Statement

The authors declare no conflicts of interest.

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