First documented case of equine brucellosis in Libya: a case report.
Abstract: This case report documents the first identified Brucella infection in a 6-year-old male Thoroughbred horse in Libya. The horse exhibited muscle and joint pain, inflammation over the shoulders with a pulpy texture (fistulous withers), stress, fatigue, and potential systemic infection. Its diagnosis was confirmed through serological testing, with agglutination titers of 1/80 for B. melitensis and 1/160 for B. abortus, and a blood culture revealing Gram-negative coccobacilli. After 3 weeks of combination therapy with rifampicin and doxycycline, the inflammation resolved, systemic signs disappeared, the horse's health improved significantly, with restored appetite and reduced levels of stress and fatigue. This novel finding underscores the potential spread of brucellosis across animal species, highlighting brucellosis' spread across animal species and its public health risks. It emphasizes the urgent need for a "One Health" approach, vaccination programs, enhanced diagnostic infrastructure, and international collaboration.
©2025 The Japanese Society of Equine Science.
Publication Date: 2025-12-16 PubMed ID: 41409900PubMed Central: PMC12705303DOI: 10.1294/jes.36.129Google Scholar: Lookup
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Cite This Article
APA
Hiblu MA, Ahmed MO.
(2025).
First documented case of equine brucellosis in Libya: a case report.
J Equine Sci, 36(4), 129-132.
https://doi.org/10.1294/jes.36.129 Publication
Researcher Affiliations
- Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, P.O. Box 13662, Libya.
- Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, P.O. Box 13662, Libya.
References
This article includes 13 references
- Abdel-Hamid N.H., Zaffan M.R., Hamdy M.E., Sabry M.A., Abdelhalem M.H., Elshiekh A.Y., Elmonir W., Hashad M.E.n2024. Antimicrobial susceptibility testing and molecularngenotyping of Brucella melitensis isolates at the human-animal interface in Upper Egyptnand Egyptian boundaries. 55:n1–11.
- Abdesalam W.M., Shahlol A.M., Dhawi A.D., Hiblu M.A., Elkady A.A., Daw M.A., Abouzeed Y.M., Ahmed M.O.n2025. Sero-epidemiological study of brucellosis in goats fromnWadi Al Shati District in the Sahara region of Libya.n 17:n6.
- Ahmed M.O., Abouzeed Y.M., Bennour E.M., van Velkinburgh J.C.n2015. Brucellosis update in Libya and regionalnprospective. 109: 39–40.nn
- Ahmed M.O., Elmeshri S.E., Abuzweda A.R., Blauo M., Abouzeed Y.M., Ibrahim A., Salem H., Alzwam F., Abid S., Elfahem A., Elrais A.n2010. Seroprevalence of brucellosis in animals and humannpopulations in the western mountains region in Libya, Decembern2006–January 2008. 15: 19625.n
- Alshekh K.A., Shahlol A.M., Mostafa K.K.B., Othman A.A., Hiblu M.A., Abouzeed Y.M., Daw M.A., Ahmed M.O.n2024. Seroprevalence of brucellosis in sheep and goats from AlnJufrah district in Libya. 48: 23. n
- Ardo M.B., Abubakar D.M.n2016. Seroprevalence of horse (Equus caballus) brucellosis onnthe Mambilla plateau of Taraba State, Nigeria. 27: 1–6.nn
- Dorneles E.M.S., Santana J.A., Costa A.C.T.R.B., Junqueira D.G., Heinemann M.B., Lage A.P.n2023. Equine brucellosis: current understanding andnchallenges. 127: 104298. n
- Karthik K., Prabakar G., Bharathi R., Kumar S.n2016. Equine brucellosis: review on epidemiology,npathogenesis, clinical signs, prevention and control. 4:nS151–S160.
- Nicoletti P.n2010. Control, eradication and prevention of brucellosis in animals and man.npp. 255–275. : Brucellosis: Recent developments towards one health.nSpringer, Berlin.
- Radostits O.M., Gay C.C., Hinchcliff K.W., Constable P.D. 2007. Veterinary medicine: A textbook of the diseases of cattle, horses, sheep, pigs and goats, 10th ed. Saunders Elsevier, London.
- Weiss D.J., Wardrop K.J. 2010. Schalm’s veterinary hematology, 6th ed. Wiley-Blackwell, Hoboken.
- Amini M., Alamian S., Talebhemmat M., Dadar M.n2024. Equine brucellosis in Iran: serological, bacteriologicalnand molecular analysis. 48: 1511–1519.nn
- Junqueira D.G., Jr, Dorneles E.M., Gonçalves V.S., Santana J.A., Almeida V.M., Nicolino R.R., Silva M.X., Mota A.L., Veloso F.P., Stynen A.P., Heinemann M.B., Lage A.P.n2015. Brucellosis in working equines of cattle farms fromnMinas Gerais State, Brazil. 121: 380–385.nn
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