Free, autologous, skin transplantation in the horse.
Abstract: Seven pieces of autologous skin were transplanted onto freshly created, full thickness skin defects on the limbs and back of a one-year-old, male, piebald, Shetland pony. The transplantations were completed in two operative sessions, the transplants on the left side were done in the first session and the right side in the second. The sizes of the transplants varied from 20 sq cm to 2 sq cm and their thicknesses from whole skin to very thin, split skin. Donor sites were both rumps and the right side of the neck. Six of the seven grafts and two thirds of the remaining graft, were accepted. Both whole thickness transplants grew hair, whereas no hair growth was detected at the 26th and 16th week following surgery on the split thickness transplants placed on the left and right sides respectively. The full thickness donor sites healed by granulation, contraction and epithelialisation. Healing at the split skin donor sites was rapid and uneventfull, epithelialisation being completed within one week and hair growth manifest by one month.
Publication Date: 1976-02-07 PubMed ID: 769301DOI: 10.1136/vr.98.6.105Google Scholar: Lookup
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- Journal Article
Summary
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The study explores the results of self-donated skin (autologous) transplantations for treating large skin defects in a one-year-old male Shetland pony. This experiment involved transplanting seven pieces of skin of varying sizes and thicknesses, with a majority of the grafts being successfully accepted and showing hair growth.
Research Methodology
- The study involved transplanting seven pieces of autologous skin onto the back and limbs of a one-year-old male, piebald, Shetland pony to treat broadly and freshly created skin defects.
- The process was carried out in two operating sessions. The first session dealt with transplants on the left side of the horse, while the second session was for the right side.
- The researchers used grafts ranging in size from 20 sq cm to 2 sq cm and varied in thickness from whole skin to very thin, split skin. Donor sites were the pony’s rumps and the right side of the neck.
Results of the Study
- Out of the seven grafts transplanted, six were fully accepted by the pony’s body, with two-thirds of the remaining graft being accepted as well.
- Whole thickness transplants led to hair growth, marking a successful transplantation. However, no hair growth was observed on the thinner, split thickness transplants even after 26 and 16 weeks post-surgery on the left and right sides, respectively.
- Donor sites from where the full thickness grafts were taken healed via granulation, contraction, and epithelialisation.
- The split skin donor sites healed rapidly and without complications, with the process of epithelialisation completing within a week and hair growth noticeable by one month.
Conclusion
- The successful acceptance of majority grafts including hair growth on some indicates promising potential for autologous skin transplantation in horses.
- The difference in healing and hair growth observed between whole thickness and split thickness grafts could provide valuable insight into choosing the appropriate graft size and thickness for future transplantations.
Cite This Article
APA
Frankland AL, Morris PG, Spreull JS.
(1976).
Free, autologous, skin transplantation in the horse.
Vet Rec, 98(6), 105-110.
https://doi.org/10.1136/vr.98.6.105 Publication
Researcher Affiliations
MeSH Terms
- Animals
- Hair / growth & development
- Horses
- Male
- Skin / anatomy & histology
- Skin Transplantation
- Transplantation, Autologous
Citations
This article has been cited 1 times.- French DA, Fretz PB. Treatment of equine leg wounds using skin grafts: Thirty-five cases, 1975-1988. Can Vet J 1990 Nov;31(11):761-5.
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