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Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2018; 30(4); 565-568; doi: 10.1177/1040638717753495

Frequency of Equus caballus papillomavirus in equine aural plaques.

Abstract: Despite the reported association between aural plaques and the presence of Equus caballus papillomavirus (EcPV), there are few data regarding the distribution of viral types in different geographic regions or possible correlations for different papillomaviruses and lesion characteristics. We detected the presence and frequency of EcPV (1-7) DNA in aural plaque biopsies of horses from different regions of Brazil and identified the patterns of these infections or coinfections and their possible association with lesion severity. A total of 108 aural plaque biopsies from horses in the 5 geopolitical regions of Brazil were examined. We performed PCR to detect EcPV DNA in the biopsies. At least 1 type of EcPV was detected in 97% of the samples. EcPV coinfection was observed in 59% of the samples. Compared to the other viruses, EcPV-4 was found at the highest frequency in coinfection (84%) or individually identified (32%). EcPV-2 and -7 were not detected. No significant association was found between lesion characteristics (type and distribution) and either the viral type detected or the presence of coinfection. EcPV is widely distributed in Brazil, both isolated and in coinfection; the viral type does not appear to influence the clinical characteristics of equine aural plaques.
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Publication Date: 2018-03-30 PubMed ID: 29601778PubMed Central: PMC6505913DOI: 10.1177/1040638717753495Google Scholar: Lookup
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Summary

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This research article studies the presence and distribution of the Equus caballus papillomavirus (EcPV) in horses’ aural plaques across different regions of Brazil and observes whether there is any correlation between different types of this virus and the characteristics of the lesions.

Equus Caballus Papillomavirus in Equine Aural Plaques

  • The research investigates the frequency and types of EcPV DNA in aural plaque biopsies taken from horses in five separate geographical regions of Brazil.
  • Equus caballus papillomavirus (EcPV) is a virus that affects horses, specifically causing aural plaques, which are lesions in the ear canal. Although an association between EcPV and aural plaques has been reported, detailed data is lacking regarding the distribution of different types of this virus in various geographical areas.
  • A total of 108 aural plaque biopsies were acquired from horses for this study. The presence of EcPV DNA in these biopsies was detected using a technique called Polymerase Chain Reaction (PCR).

Results and Findings

  • At least one type of EcPV was found in 97% of the biopsies, which indicated a very high prevalence of this virus among the equine population in Brazil.
  • Multiple (co-infection) variations of the virus were detected in 59% of the samples. Among different types of viruses, EcPV-4 was most commonly found either in co-infection (84%) or as an individually identified type (32%).
  • Notably, two forms of the virus, EcPV-2 and EcPV-7, were not detected in any of the samples.
  • Interestingly, the study found that there was no significant correlation between the characteristics of the lesions (such as type and distribution) and either the viral type detected or the presence of co-infection.

Conclusions

  • The research concludes that EcPV is widely distributed in Brazil, with the viral type not appearing to influence the clinical characteristics of equine aural plaques.
  • Further studies may be required to better understand the implications of EcPV co-infections and the mechanisms that determine lesion characteristics in equine aural plaques.

Cite This Article

APA
Mira J, Herman M, Zakia LS, Olivo G, Araújo JP, Borges AS, Oliveira-Filho JP. (2018). Frequency of Equus caballus papillomavirus in equine aural plaques. J Vet Diagn Invest, 30(4), 565-568. https://doi.org/10.1177/1040638717753495

Publication

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
ISSN: 1943-4936
NlmUniqueID: 9011490
Country: United States
Language: English
Volume: 30
Issue: 4
Pages: 565-568

Researcher Affiliations

Mira, Juliana
  • School of Veterinary Medicine and Animal Science (Mira, Herman, Zakia, Olivo, Borges, Oliveira-Filho), Botucatu, Brazil.
  • Institute of Biosciences (Araújo Jr), Botucatu, Brazil.
  • São Paulo State University (Unesp), Botucatu, Brazil.
  • Research Group in Veterinary Medicine - GIVET, School of Veterinary Medicine, Unilasallista-Corporación Universitaria Lasallista, Caldas-Antioquia, Colombia (Mira).
Herman, Mariana
  • School of Veterinary Medicine and Animal Science (Mira, Herman, Zakia, Olivo, Borges, Oliveira-Filho), Botucatu, Brazil.
  • Institute of Biosciences (Araújo Jr), Botucatu, Brazil.
  • São Paulo State University (Unesp), Botucatu, Brazil.
  • Research Group in Veterinary Medicine - GIVET, School of Veterinary Medicine, Unilasallista-Corporación Universitaria Lasallista, Caldas-Antioquia, Colombia (Mira).
Zakia, Luiza S
  • School of Veterinary Medicine and Animal Science (Mira, Herman, Zakia, Olivo, Borges, Oliveira-Filho), Botucatu, Brazil.
  • Institute of Biosciences (Araújo Jr), Botucatu, Brazil.
  • São Paulo State University (Unesp), Botucatu, Brazil.
  • Research Group in Veterinary Medicine - GIVET, School of Veterinary Medicine, Unilasallista-Corporación Universitaria Lasallista, Caldas-Antioquia, Colombia (Mira).
Olivo, Giovane
  • School of Veterinary Medicine and Animal Science (Mira, Herman, Zakia, Olivo, Borges, Oliveira-Filho), Botucatu, Brazil.
  • Institute of Biosciences (Araújo Jr), Botucatu, Brazil.
  • São Paulo State University (Unesp), Botucatu, Brazil.
  • Research Group in Veterinary Medicine - GIVET, School of Veterinary Medicine, Unilasallista-Corporación Universitaria Lasallista, Caldas-Antioquia, Colombia (Mira).
Araújo, João P
  • School of Veterinary Medicine and Animal Science (Mira, Herman, Zakia, Olivo, Borges, Oliveira-Filho), Botucatu, Brazil.
  • Institute of Biosciences (Araújo Jr), Botucatu, Brazil.
  • São Paulo State University (Unesp), Botucatu, Brazil.
  • Research Group in Veterinary Medicine - GIVET, School of Veterinary Medicine, Unilasallista-Corporación Universitaria Lasallista, Caldas-Antioquia, Colombia (Mira).
Borges, Alexandre S
  • School of Veterinary Medicine and Animal Science (Mira, Herman, Zakia, Olivo, Borges, Oliveira-Filho), Botucatu, Brazil.
  • Institute of Biosciences (Araújo Jr), Botucatu, Brazil.
  • São Paulo State University (Unesp), Botucatu, Brazil.
  • Research Group in Veterinary Medicine - GIVET, School of Veterinary Medicine, Unilasallista-Corporación Universitaria Lasallista, Caldas-Antioquia, Colombia (Mira).
Oliveira-Filho, José P
  • School of Veterinary Medicine and Animal Science (Mira, Herman, Zakia, Olivo, Borges, Oliveira-Filho), Botucatu, Brazil.
  • Institute of Biosciences (Araújo Jr), Botucatu, Brazil.
  • São Paulo State University (Unesp), Botucatu, Brazil.
  • Research Group in Veterinary Medicine - GIVET, School of Veterinary Medicine, Unilasallista-Corporación Universitaria Lasallista, Caldas-Antioquia, Colombia (Mira).

MeSH Terms

  • Animals
  • Brazil / epidemiology
  • Horse Diseases / pathology
  • Horse Diseases / virology
  • Horses
  • Papillomaviridae / genetics
  • Papillomaviridae / isolation & purification
  • Papillomavirus Infections / pathology
  • Papillomavirus Infections / veterinary
  • Papillomavirus Infections / virology
  • Polymerase Chain Reaction / veterinary

Conflict of Interest Statement

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Citations

This article has been cited 6 times.
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