FREE SHIPPING over $40
OVER 10000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Canadian journal of comparative medicine : Revue canadienne de medecine comparee1976; 40(1); 12-15;

Fusariotoxicosis from barley in British Columbia. I. Natural occurrence and diagnosis.

Abstract: Clinical sickness was observed in domestic ducks, geese, horses and swine during October 1973. All species showed upper alimentary distress with mortalities occurring in the geese. Barley derived from a common source had been fed. Examination of the barley revealed invasion by Fusarium spp and detection of a high level of dermatitic fusariotoxins.
Get Full Text
Publication Date: 1976-01-01 PubMed ID: 1000372PubMed Central: PMC1277512
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article explores a case of Fusariotoxicosis, a poisoning caused by toxic compounds produced by Fusarium fungi, observed in different farm animals in British Columbia in 1973. All the sick animals had been fed barley from a common source, confirmed to be infested with the Fusarium fungi and high levels of dermatitic fusariotoxins.

Introduction

  • The study revolves around a case of Fusariotoxicosis diagnosed in different species of domestic animals in British Columbia in October 1973.
  • The animals had consumed barley derived from a common source, which was later determined to be contaminated with both Fusarium spp and a high concentration of dermatitic fusariotoxins – toxic compounds produced by species in the Fusarium genus of fungi.

Observations

  • The researchers inferred that domestic animals including ducks, geese, horses, and swine suffered from Fusariotoxicosis after consuming the infested barley.
  • They all exhibited signs of upper alimentary distress, with fatalities occurring among the geese population.

Detection and Diagnosis

  • The team carried out diagnostic examinations to detect the cause of the illness.
  • These investigative procedures led them to the diagnosis that the animal sickness was a result of Fusariotoxicosis.
  • Examination of the common source of barley confirmed the presence of Fusarium spp.
  • Further investigation revealed that these grains were also heavily laden with dermatitic fusariotoxins, which are toxic compounds capable of causing serious health effects in both animals and humans.

Conclusions

  • The researchers concluded that the clinical sickness in the farm animals was caused by the ingestion of barley contaminated with Fusarium fungi and a high dose of dermatitic fusariotoxins.
  • Fusariotoxicosis poses a significant risk to the health and survival of such animals, as evidenced by the observed mortalities among the geese.

Cite This Article

APA
Greenway JA, Puls R. (1976). Fusariotoxicosis from barley in British Columbia. I. Natural occurrence and diagnosis. Can J Comp Med, 40(1), 12-15.

Publication

Canadian journal of comparative medicine : Revue canadienne de medecine comparee
ISSN: 0008-4050
NlmUniqueID: 0151747
Country: Canada
Language: English
Volume: 40
Issue: 1
Pages: 12-15

Researcher Affiliations

Greenway, J A
    Puls, R

      MeSH Terms

      • Animal Feed / poisoning
      • Animals
      • British Columbia
      • Ducks
      • Edible Grain / poisoning
      • Fusarium / isolation & purification
      • Geese
      • Hordeum / poisoning
      • Horse Diseases / etiology
      • Horses
      • Mycotoxins
      • Poultry Diseases / etiology
      • Swine
      • Swine Diseases / etiology

      References

      This article includes 18 references
      1. Puls R, Greenway JA. Fusariotoxicosis from barley in British Columbia. II. Analysis and toxicity of syspected barley.. Can J Comp Med 1976 Jan;40(1):16-9.
        pubmed: 1000373
      2. Hsu IC, Smalley EB, Strong FM, Ribelin WE. Identification of T-2 toxin in moldy corn associated with a lethal toxicosis in dairy cattle.. Appl Microbiol 1972 Nov;24(5):684-90.
        pubmed: 4640734doi: 10.1128/am.24.5.684-690.1972google scholar: lookup
      3. Tookey HL, Yates SG, Ellis JJ, Grove MD, Nichols RE. Toxic effects of a butenolide mycotoxin and of Fusarium tricinctum cultures in cattle.. J Am Vet Med Assoc 1972 Jun 1;160(11):1522-6.
        pubmed: 5027735
      4. Kosuri NR, Grove MD, Yates SG, Tallent WH, Ellis JJ, Wolff IA, Nichols RE. Response of cattle to mycotoxins of Fusarium tricinctum isolated from corn and fescue.. J Am Vet Med Assoc 1970 Oct 1;157(7):938-40.
        pubmed: 5472343
      5. Caldwell RW, Tuite J, Stob M, Baldwin R. Zearalenone production by Fusarium species.. Appl Microbiol 1970 Jul;20(1):31-4.
        pubmed: 5456939doi: 10.1128/am.20.1.31-34.1970google scholar: lookup
      6. Lillehoj EB. Feed sources and conditions conducive to production of aflatoxin, ochratoxin, Fusarium toxins, and zearalenone.. J Am Vet Med Assoc 1973 Dec 1;163(11):1281-4.
        pubmed: 4202609
      7. Pier AC. An overview of the mycotoxicoses of domestic animals.. J Am Vet Med Assoc 1973 Dec 1;163(11):1259-61.
        pubmed: 4206240
      8. Smalley EB. T-2 toxin.. J Am Vet Med Assoc 1973 Dec 1;163(11):1278-81.
        pubmed: 4586756
      9. Nelson GH, Christensen CM, Mirocha CJ. Fusarium and estrogenism in swine.. J Am Vet Med Assoc 1973 Dec 1;163(11):1276-7.
        pubmed: 4593857
      10. Wyatt RD, Weeks BA, Hamilton PB, Burmeister HR. Severe oral lesions in chickens caused by ingestion of dietary fusariotoxin T-2.. Appl Microbiol 1972 Aug;24(2):251-7.
        pubmed: 4561104doi: 10.1128/am.24.2.251-257.1972google scholar: lookup
      11. Vesonder RF, Ciegler A, Jensen AH. Isolation of the emetic principle from Fusarium-infected corn.. Appl Microbiol 1973 Dec;26(6):1008-10.
        pubmed: 4767291doi: 10.1128/am.26.6.1008-1010.1973google scholar: lookup
      12. Wyatt RD, Colwell WM, Hamilton PB, Burmeister HR. Neural disturbances in chickens caused by dietary T-2 toxin.. Appl Microbiol 1973 Nov;26(5):757-61.
        pubmed: 4762395doi: 10.1128/am.26.5.757-761.1973google scholar: lookup
      13. Wyatt RD, Hamilton PB, Burmeister HR. The effects of T-2 toxin in broiler chickens.. Poult Sci 1973 Sep;52(5):1853-9.
        pubmed: 4760739doi: 10.3382/ps.0521853google scholar: lookup
      14. Ellison RA, Kotsonis FN. T-2 toxin as an emetic factor in moldy corn.. Appl Microbiol 1973 Oct;26(4):540-3.
        pubmed: 4751800doi: 10.1128/am.26.4.540-543.1973google scholar: lookup
      15. Ueno Y, Sato N, Ishii K, Sakai K, Tsunoda H. Biological and chemical detection of trichothecene mycotoxins of Fusarium species.. Appl Microbiol 1973 Apr;25(4):699-704.
        pubmed: 4699224doi: 10.1128/am.25.4.699-704.1973google scholar: lookup
      16. Wyatt RD, Harris JR, Hamilton PB, Burmeister HR. Possible outbreaks of fusariotoxicosis in avians.. Avian Dis 1972 Oct-Dec;16(5):1123-30.
        pubmed: 4640184
      17. Christensen CM, Meronuck RA, Nelson GH, Behrens JC. Effects on turkey poults of rations containing corn invaded by Fusarium tricinctum (Cda.) Sny. & Hans.. Appl Microbiol 1972 Jan;23(1):177-9.
        pubmed: 5059619doi: 10.1128/am.23.1.177-179.1972google scholar: lookup
      18. Burmeister HR, Ellis JJ, Yates SG. Correlation of biological to chromatographic data for two mycotoxins elaborated by Fusarium.. Appl Microbiol 1971 Apr;21(4):673-5.
        pubmed: 5575569doi: 10.1128/am.21.4.673-675.1971google scholar: lookup

      Citations

      This article has been cited 14 times.
      1. Zhang J, Zhang H, Liu S, Wu W, Zhang H. Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol. Toxins (Basel) 2018 Apr 29;10(5).
        doi: 10.3390/toxins10050179pubmed: 29710820google scholar: lookup
      2. Wu W, Zhou HR, Pan X, Pestka JJ. Comparison of Anorectic Potencies of the Trichothecenes T-2 Toxin, HT-2 Toxin and Satratoxin G to the Ipecac Alkaloid Emetine. Toxicol Rep 2015;2:238-251.
        doi: 10.1016/j.toxrep.2014.12.010pubmed: 25932382google scholar: lookup
      3. Hayes MA, Schiefer HB. Subacute toxicity of Dietary T-2 toxin in mice: influence of protein nutrition. Can J Comp Med 1980 Apr;44(2):219-28.
        pubmed: 7407693
      4. Hayes MA, Bellamy JE, Schiefer HB. Subacute toxicity of dietary T-2 toxin in mice: morphological and hematological effects. Can J Comp Med 1980 Apr;44(2):203-18.
        pubmed: 7407692
      5. Hayes MA, Wobeser GA. Subacute toxic effects of dietary T-2 toxin in young mallard ducks. Can J Comp Med 1983 Apr;47(2):180-7.
        pubmed: 6883185
      6. Abramson D, Mills JT, Boycott BR. Mycotoxins and mycoflora in animal feedstuffs in western Canada. Can J Comp Med 1983 Jan;47(1):23-6.
        pubmed: 6831303
      7. Friend SC, Hancock DS, Schiefer HB, Babiuk LA. Experimental T-2 toxicosis in sheep. Can J Comp Med 1983 Jul;47(3):291-7.
        pubmed: 6640413
      8. Schappert KT, Khachatourians GG. Influence of the membrane on T-2 toxin toxicity in Saccharomyces spp. Appl Environ Microbiol 1984 Apr;47(4):681-4.
        doi: 10.1128/aem.47.4.681-684.1984pubmed: 6372690google scholar: lookup
      9. Rousseaux CG, Nicholson S, Schiefer HB. Fatal placental hemorrhage in pregnant CD-1 mice following one oral dose of T-2 toxin. Can J Comp Med 1985 Jan;49(1):95-8.
        pubmed: 3986684
      10. Boyd KE, Fitzpatrick DW, Wilson JR, Wilson LM. Effect of T-2 toxin on brain biogenic monoamines in rats and chickens. Can J Vet Res 1988 Apr;52(2):181-5.
        pubmed: 2453262
      11. Kim KH, Lee YW, Mirocha CJ, Pawlosky RJ. Isoverrucarol production by Fusarium oxysporum CJS-12 isolated from corn. Appl Environ Microbiol 1990 Jan;56(1):260-3.
        doi: 10.1128/aem.56.1.260-263.1990pubmed: 2310181google scholar: lookup
      12. Puls R, Greenway JA. Fusariotoxicosis from barley in British Columbia. II. Analysis and toxicity of syspected barley. Can J Comp Med 1976 Jan;40(1):16-9.
        pubmed: 1000373
      13. Kelman MJ, Miller JD, Renaud JB, Baskova D, Sumarah MW. A Multi-Year Study of Mycotoxin Co-Occurrence in Wheat and Corn Grown in Ontario, Canada. Toxins (Basel) 2024 Aug 22;16(8).
        doi: 10.3390/toxins16080372pubmed: 39195782google scholar: lookup
      14. Wu W, Zhou HR, Bursian SJ, Link JE, Pestka JJ. Emetic responses to T-2 toxin, HT-2 toxin and emetine correspond to plasma elevations of peptide YY3-36 and 5-hydroxytryptamine. Arch Toxicol 2016 Apr;90(4):997-1007.
        doi: 10.1007/s00204-015-1508-7pubmed: 25855062google scholar: lookup
      Subscribe to our newsletter
      Join 99,658 horse owners like you who receive our email updates on horse health and nutrition.