Gastric ulceration in an equine neonate.

Abstract: A 24-hour-old colt presented with clinical signs consistent with gastric ulceration. Treatment was initiated with a histamine type-2 receptor antagonist and clinical signs resolved. Gastroscopy at 16 d confirmed the presence of a gastric ulcer. Although gastric ulceration is common in foals, it is rarely reported in foals this young.
Publication Date: 2003-05-22 PubMed ID: 12757136PubMed Central: PMC340153
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Case Reports
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article discusses a case of a newborn colt (a male horse less than one year old) that presented symptoms of gastric ulcers, an unusual occurrence in foals of this age. The colt was treated with drugs to inhibit gastric acid production and showed a favorable response, with gastroscopy at 16 days confirming the presence of an ulcer.

Case Presentation and Initial Treatment

  • The research starts with the unusual presentation of a 24-hour old colt showing clinical signs aligning with gastric ulceration. Gastric ulceration in foals is quite common, however, such presentation in newborns is rare.
  • This clinical situation marked an unusual event inviting the attention of the researchers to record, treat and learn from the case.
  • The treatment initiates with the use of a histamine type-2 receptor antagonist. Such drugs are commonly used to treat peptic ulcers and gastro-oesophageal reflux disease (GERD) by reducing the production of stomach acid.

Outcome of the Treatment and Diagnosis Confirmation

  • Following the administration of the drugs, the colt’s clinical signs were resolved indicating a successful response to the treatment.
  • To confirm the previous diagnosis of a gastric ulcer, a gastroscopy was performed on the 16th day. This procedure allowed the researchers to visually inspect the interior of the foal’s stomach and confirm the presence of the gastric ulcer.
  • The successful diagnosis and treatment of this case added to the knowledge base for treating such rare conditions in newborn foals.

Implications of the Research

  • The unique aspect of this research is the rarity of gastric ulceration occurring in a foal this young making this case a significant contribution to veterinary medicine.
  • By successfully diagnosing and treating the gastric ulcer, this study adds to the limited pool of knowledge about gastric issues in newborn foals. It provides a case study that can help in understanding such rare situations in the future.
  • This research also raises questions about why such a young foal developed an ulcer, pointing to potential genetic or environmental risk factors that need to be considered.

Cite This Article

APA
Lewis S. (2003). Gastric ulceration in an equine neonate. Can Vet J, 44(5), 420-421.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 44
Issue: 5
Pages: 420-421

Researcher Affiliations

Lewis, Susan
  • Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.

MeSH Terms

  • Animals
  • Animals, Newborn
  • Cimetidine / therapeutic use
  • Colic / etiology
  • Colic / veterinary
  • Gastroscopy / veterinary
  • Histamine H2 Antagonists / therapeutic use
  • Horse Diseases / diagnosis
  • Horse Diseases / drug therapy
  • Horses
  • Male
  • Stomach Ulcer / diagnosis
  • Stomach Ulcer / drug therapy
  • Stomach Ulcer / veterinary

References

This article includes 7 references
  1. Freeman DE. Gastrointestinal pharmacology.. Vet Clin North Am Equine Pract 1999 Dec;15(3):535-59, vii.
    pubmed: 10589466doi: 10.1016/s0749-0739(17)30131-1google scholar: lookup
  2. Murray MJ. Gastroduodenal ulceration in foals. Equine Vet Educ 1999;11:199u2013207.
  3. Sanchez LC, Lester GD, Merritt AM. Effect of ranitidine on intragastric pH in clinically normal neonatal foals.. J Am Vet Med Assoc 1998 May 1;212(9):1407-12.
    pubmed: 9589127
  4. Stoneham SJ. Practical aspects of diarrhoea in the foal with particular reference to rotavirus and gastroduodenal ulceration. Equine Vet Educ 1996;8:84u201390.
  5. Murray MJ, Jeffery SC. Endoscopy case of the month: fever and depression in a foal. Vet Med 1998;93:76u201381.
  6. Breuhaus BA, DeGraves FJ, Honore EK, Papich MG. Pharmacokinetics of ibuprofen after intravenous and oral administration and assessment of safety of administration to healthy foals.. Am J Vet Res 1999 Sep;60(9):1066-73.
    pubmed: 10490073
  7. Murray MJ. Gastroduodenal ulceration. In: Robinson NE, ed. Current Therapy in Equine Medicine 4. Philadelphia: WB Saunders, 1997:191u2013197.

Citations

This article has been cited 1 times.
  1. Hewetson M, Venner M, Volquardsen J, Sykes BW, Hallowell GD, Vervuert I, Fosgate GT, Tulamo RM. Diagnostic accuracy of blood sucrose as a screening test for equine gastric ulcer syndrome (EGUS) in weanling foals.. Acta Vet Scand 2018 Apr 13;60(1):24.
    doi: 10.1186/s13028-018-0377-5pubmed: 29653546google scholar: lookup