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Home / Equine Research Bank / J Clin Microbiol / Genetic analysis of equine rotavirus by RNA-RNA hybridizatio...
Journal of clinical microbiology1994; 32(8); 2009-2012; doi: 10.1128/jcm.32.8.2009-2012.1994

Genetic analysis of equine rotavirus by RNA-RNA hybridization.

Abstract: Serotype G3 equine rotaviruses isolated in Japan made up a common genogroup and were classified into two different genotypes. The genomes of serotype G3 equine rotaviruses with an identical electropherotype (isolated from 1982 to 1989) were very closely related to each other regardless of the year in which they were isolated. Serotype G3 equine rotavirus BI originating from England belonged to the same genogroup of serotype G3 equine rotaviruses isolated in Japan, although BI was classified as having a different genotype. The genomes of both serotype G10 equine rotavirus R-22 and serotype G10 calf rotavirus were closely related to each other.
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Publication Date: 1994-08-01 PubMed ID: 7989559PubMed Central: PMC263921DOI: 10.1128/jcm.32.8.2009-2012.1994Google Scholar: Lookup
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  • Comparative Study
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article discusses the genetic analysis of equine rotavirus, a virus that causes diarrhoea in horses. The study found that certain serotypes of the virus isolated in Japan shared common genetic traits and that these traits were largely consistent across different years of isolation.

Study Overview

  • The research focused on serotype G3 equine rotaviruses—specific variations of the virus—that were isolated in Japan.
  • Researchers categorized these serotype G3 equine rotaviruses into a single genogroup, but differentiated them into two genotypes.
  • The study found that these rotaviruses shared closely related genomes, irrespective of the year of their isolation. This suggests a notable level of genetic stability among these viruses over time.

Comparison with Other Variations

  • A specific serotype G3 equine rotavirus called BI, originating from England, was analyzed and found to belong to the same genogroup as the ones isolated in Japan.
  • However, the BI virus was classified into a different genotype. This indicates that while they may belong to the same larger group, there are genetic differences between the viruses isolated in Japan and the BI virus from England.
  • Furthermore, the research found close genetic relations between the genomes of serotype G10 equine rotavirus and serotype G10 calf rotavirus. This suggests a possible shared ancestry or similar evolutionary paths for these viruses.

Implications of the Research

  • Understanding the genetic structure and relations of these viruses can contribute to the development of more effective treatments and preventive measures against equine rotavirus.
  • The genetic consistency over time signifies that historic isolates might still be relevant for current research and development of treatments.
  • The close relation between equine and calf rotavirus could imply that findings from one could possibly be applied to the other, broadening the scope of potential benefits from this research.

Cite This Article

APA
Imagawa H, Ishida S, Uesugi S, Masanobu K, Fukunaga Y, Nakagomi O. (1994). Genetic analysis of equine rotavirus by RNA-RNA hybridization. J Clin Microbiol, 32(8), 2009-2012. https://doi.org/10.1128/jcm.32.8.2009-2012.1994

Publication

Journal of clinical microbiology
ISSN: 0095-1137
NlmUniqueID: 7505564
Country: United States
Language: English
Volume: 32
Issue: 8
Pages: 2009-2012

Researcher Affiliations

Imagawa, H
  • Epizootic Research Station, Equine Research Institute, Japan Racing Association, Tochigi.
Ishida, S
    Uesugi, S
      Masanobu, K
        Fukunaga, Y
          Nakagomi, O

            MeSH Terms

            • Animals
            • Cattle
            • Cattle Diseases / epidemiology
            • Cattle Diseases / virology
            • England / epidemiology
            • Horse Diseases / epidemiology
            • Horse Diseases / virology
            • Horses
            • Japan / epidemiology
            • Nucleic Acid Hybridization
            • RNA, Viral / genetics
            • Rotavirus / classification
            • Rotavirus / genetics
            • Rotavirus Infections / epidemiology
            • Rotavirus Infections / veterinary
            • Serotyping

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            Citations

            This article has been cited 8 times.
            1. Pathak A, Gulati BR, Maan S, Mor S, Kumar D, Soman R, Punia S, Chaudhary D, Khurana SK. Complete Genome Sequencing Reveals Unusual Equine Rotavirus A of Bat Origin from India.. J Virol 2022 Oct 26;96(20):e0140822.
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