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Giardiasis in a horse.

Abstract: Giardia infection was believed responsible for chronic diarrhea, weight loss, lethargy, inappetence, and dermatitis in a 4-year-old Thoroughbred horse. Fecal cysts were detected by the zinc sulfate centrifugal flotation method. All clinical signs resolved upon treatment with metronidazole suspension (5 mg/kg body weight per os, TID for 10 days).
Publication Date: 1985-07-15 PubMed ID: 4030452
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Summary

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The research article discusses a case where a horse was found to be suffering from Giardiasis, a parasitic infection, which manifested through symptoms like constant diarrhea, loss of weight, lethargy, lack of appetite, and skin inflammation. The infections was treated successfully using metronidazole, a medication commonly used to treat infections caused by bacteria and parasites.

Identification of Giardiasis

  • The paper talks about a 4-year-old thoroughbred horse suffering from clinical signs such as chronic diarrhea, lethargy, weight loss, inappetence (lack of appetite) and dermatitis (skin inflammation).
  • These symptoms led the researchers to believe the horse was infected with Giardia, a microscopic parasite that causes the diarrheal illness known as Giardiasis.
  • A test termed as the ‘zinc sulfate centrifugal flotation method’ helped in diagnosing the infection. This is a laboratory procedure used to isolate the cysts of Giardia from the feces of the horse.

Treatment & Recovery

  • Metronidazole suspension was administered to the horse as treatment. Metronidazole is an antibiotic effective against anaerobic bacteria and specific parasites, including Giardia.
  • The prescribed dosage was 5 mg/kg body weight per os, or orally, three times a day (TID), administered over a period of 10 days.
  • The treatment resulted in the resolution of all clinical signs, implying successful recovery from the Giardia infection.

Research Implication

  • This case study serves to provide evidence that Giardiasis can affect horses in much the same way it does humans and other animals.
  • It highlights the significance of prompt diagnosis and treatment of Giardiasis in mitigating the infection and facilitating recovery.
  • The successful therapeutic use of metronidazole can also serve as a viable treatment solution for Giardiasis in horses in future clinical scenarios.

Cite This Article

APA
Kirkpatrick CE, Skand DL. (1985). Giardiasis in a horse. J Am Vet Med Assoc, 187(2), 163-164.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 187
Issue: 2
Pages: 163-164

Researcher Affiliations

Kirkpatrick, C E
    Skand, D L

      MeSH Terms

      • Animals
      • Dermatitis / drug therapy
      • Dermatitis / veterinary
      • Diarrhea / drug therapy
      • Diarrhea / veterinary
      • Giardiasis / diagnosis
      • Giardiasis / drug therapy
      • Giardiasis / veterinary
      • Horse Diseases / diagnosis
      • Horse Diseases / drug therapy
      • Horses
      • Male
      • Metronidazole / therapeutic use

      Citations

      This article has been cited 5 times.
      1. Deng L, Li W, Zhong Z, Liu X, Chai Y, Luo X, Song Y, Wang W, Gong C, Huang X, Hu Y, Fu H, He M, Wang Y, Zhang Y, Wu K, Cao S, Peng G. Prevalence and molecular characterization of Giardia intestinalis in racehorses from the Sichuan province of southwestern China. PLoS One 2017;12(12):e0189728.
        doi: 10.1371/journal.pone.0189728pubmed: 29261753google scholar: lookup
      2. Rayan P, Stenzel D, McDonnell PA. The effects of saturated fatty acids on Giardia duodenalis trophozoites in vitro. Parasitol Res 2005 Oct;97(3):191-200.
        doi: 10.1007/s00436-005-1432-5pubmed: 15991042google scholar: lookup
      3. Conboy G. Giardia. Can Vet J 1997 Apr;38(4):245-7.
        pubmed: 9213531
      4. Granstrom DE. Recent advances in the laboratory diagnosis of equine parasitic diseases. Vet Clin North Am Equine Pract 1995 Dec;11(3):437-42.
        doi: 10.1016/s0749-0739(17)30309-7pubmed: 8925419google scholar: lookup
      5. Flanagan PA. Giardia--diagnosis, clinical course and epidemiology. A review. Epidemiol Infect 1992 Aug;109(1):1-22.
        pubmed: 1499664