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Equine veterinary journal. Supplement2007; (36); 643-647; doi: 10.1111/j.2042-3306.2006.tb05619.x

Glycaemic and insulinaemic response of quarter horses to concentrates high in fat and low in soluble carbohydrates.

Abstract: Quarter Horses are particularly susceptible to polysaccharide storage myopathy (PSSM). Nutritional therapy and possibly prophylaxis includes fat-supplemented diets whilst starch supply should be kept to a minimum. Objective: To investigate the glycaemic and insulinaemic response of clinically normal Quarter Horses to concentrates high in fat and low in starch. Methods: Twelve Quarter Horses were studied. The precondition for inclusion in the study population was that the horses had not shown clinical signs of myopathy. The Quarter Horses were fed according to a 4 x 4 Latin square design haylage plus isocaloric concentrates based on barley and oats as control (CO), sugar beet pulp, grass meal and soybean oil (SB), rice bran and grass meal (RB) and rice bran, grass meal, sugar beet pulp and soybean oil (CP), each over 2 weeks after 1 week of adaptation. At the end of each period, 1 kg of concentrate was fed and blood sampled 0, 30, 60, 90, 120, 180, 240, and 300 min post prandial (ppr.). Creatine kinase (CK; 0 min ppr. only), glucose and insulin were analysed. Glycaemic and insulinaemic index was calculated from each concentrates area under the curve (AUC) relative to CO. Results: Rice bran containing concentrates were partially refused at the beginning of the trial periods. CK activity, and glucose and insulin patterns (ppr. mean, peak, AUC, index) were highest with CO (P<0.05). The correlation between glucose and insulin (P<0.001) ranged from r = 0.570 (CO) to r = 0.364 (RB). Basal CK was highly correlated (P<0.001) to the mean ppr. plasma glucose. Conclusions: Rice bran, sugar beet pulp, grass meal and soybean oil are suitable to include in concentrates that induce low glycaemic and insulinaemic response. Its acceptance seems to be a question of habituation. Although the mechanism is not completely understood, glucose patterns and basal CK activity are highly positively correlated. Both were affected by the type of concentrate used. Conclusions: Results support the suggestion that low-starch and high-fat feeding may be helpful not only in the nutrition of affected horses, but also to prevent future PSSM associated discomfort in particularly susceptible horses.
Publication Date: 2007-04-04 PubMed ID: 17402498DOI: 10.1111/j.2042-3306.2006.tb05619.xGoogle Scholar: Lookup
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  • Journal Article
  • Randomized Controlled Trial

Summary

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The research investigates how glycemic and insulinaemic responses in healthy Quarter Horses are affected by feeds high in fat and low in starch. The study results suggest that such diet may prevent future discomfort associated with Polysaccharide Storage Myopathy (PSSM), a common horse ailment.

Study Objective and Methodology

  • The aim of the study was to understand how the blood sugar and insulin levels of Quarter Horses respond to high fat, low starch feeds, given that these horses are more prone to PSSM.
  • Twelve clinically healthy Quarter Horses were observed. All of these horses had no prior signs of myopathy, a muscle disease which PSSM is a type of.
  • The horses were fed on a 4 x 4 Latin square design haylage along with isocaloric concentrates based on barley and oats as a control diet (CO). Additionally, they also received diets high in sugar beet pulp, grass meal, and soybean oil (SB), rice bran and grass meal (RB), and rice bran, grass meal, sugar beet pulp and soybean oil (CP).
  • The feeds were given over two weeks after a week of acclimatization. At the end of each period, blood samples were collected at intervals – 0, 30, 60, 90, 120, 180, 240, and 300 minutes after feeding.
  • Blood test parameters included creatine kinase level (muscle damage indicator), glucose and insulin levels.

Results and Findings

  • It was observed that the horses initially resisted rice bran containing feeds, but gradually accepted them over time.
  • The assessments of creatine kinase activity, glucose and insulin levels were highest with the control diet (CO).
  • The correlation between glucose and insulin levels varied with the type of feed but was significant overall, suggesting that the type of feed influenced the relationship between glucose and insulin.
  • Moreover, the researchers found a strong correlation between the creatine kinase levels at feeding time and the mean post-prandial plasma glucose levels.

Conclusions

  • The study concludes that feeds inclusive of rice bran, sugar beet pulp, grass meal and soybean oil are effective in inducing low glycaemic and insulinaemic responses. However, a degree of acclimation is required for the horses to accept such feeds.
  • Though the underlying mechanism is not completely understood, the researchers found that the type of feed affects both glucose patterns and basal creatine kinase activity.
  • The results from the study support the idea that low-starch, high-fat feeding may not only be beneficial for affected horses but could also act as a preventive measure against PSSM in susceptible horses.

Cite This Article

APA
Zeyner A, Hoffmeister C, Einspanier A, Gottschalk J, Lengwenat O, Illies M. (2007). Glycaemic and insulinaemic response of quarter horses to concentrates high in fat and low in soluble carbohydrates. Equine Vet J Suppl(36), 643-647. https://doi.org/10.1111/j.2042-3306.2006.tb05619.x

Publication

NlmUniqueID: 9614088
Country: United States
Language: English
Issue: 36
Pages: 643-647

Researcher Affiliations

Zeyner, A
  • Institute of Animal Nutrition, Nutritional Diseases and Dietetics, University of Leipzig, Leipzig, Germany.
Hoffmeister, C
    Einspanier, A
      Gottschalk, J
        Lengwenat, O
          Illies, M

            MeSH Terms

            • Animals
            • Area Under Curve
            • Blood Glucose / metabolism
            • Creatine Kinase / metabolism
            • Cross-Over Studies
            • Dietary Carbohydrates / administration & dosage
            • Dietary Carbohydrates / metabolism
            • Dietary Carbohydrates / pharmacokinetics
            • Dietary Fats / administration & dosage
            • Dietary Fats / metabolism
            • Dietary Fats / pharmacokinetics
            • Female
            • Horse Diseases / diet therapy
            • Horses / metabolism
            • Insulin / metabolism
            • Male
            • Postprandial Period
            • Rhabdomyolysis / diet therapy
            • Rhabdomyolysis / veterinary
            • Solubility

            Citations

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