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International journal of medical microbiology : IJMM2002; 291 Suppl 33; 100-103; doi: 10.1016/s1438-4221(02)80019-4

Granulocytic ehrlichiosis in Swedish dogs and horses.

Abstract: Granulocytic ehrlichiosis is a frequently diagnosed tick-borne disease in Swedish dogs and horses. The infection is caused by a granulocytic Ehrlichia species belonging to the Ehrlichia phagocytophila genogroup. In the acute stage, the disease is mainly characterized as a febrile illness and diagnosis can be confirmed by the demonstration of ehrlichial inclusions in blood granulocytes. Seropositivity in many healthy dogs and horses indicate that the infection also can be transient without clinical signs. The infection can persist in experimentally inoculated animals for months, but to what extent this persistance also occurs in naturally infected animals and is associated with clinical signs, is not clarified yet.
Publication Date: 2002-07-27 PubMed ID: 12141731DOI: 10.1016/s1438-4221(02)80019-4Google Scholar: Lookup
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Summary

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The research article discusses Granulocytic ehrlichiosis, a common tick-borne disease found in Swedish dogs and horses, caused by the Ehrlichia phagocytophila genogroup. The research is based on studying the disease’s symptoms, diagnosis methods, and its possible persistence in affected animals.

Ehrlichia Phagocytophila Genogroup

  • Ehrlichia phagocytophila, a member of the Ehrlichia genogroup, is the specific organism that causes granulocytic ehrlichiosis in Swedish dogs and horses.
  • It is a tick-borne microorganism that infects the white blood cells of these animals, detrimentally affecting their health.

Characteristics of the Disease

  • The disease primarily presents itself as a febrile illness during its acute stage, meaning it is usually associated with a high fever and related symptoms.
  • Secondary symptoms are not discussed explicitly in the abstract but associated signs of the disease may include lethargy, loss of appetite, and in severe cases, respiratory distress.

Diagnosis

  • Diagnosis can be confirmed through a visual confirmation of ehrlichial inclusions in the infected animal’s granulocytes, a type of white blood cells, examining under a microscope.
  • A positive serological test may also confirm the infection as it shows the animal’s immune response to the disease.

Persistence of the Infection

  • The research indicates that not all animals who test positive for Ehrlichiosis show signs of illness, suggesting that the infection can be transient without clear clinical symptoms. This point is particularly significant as silent carriers can serve as constant disease reservoirs for spreading the bacteria.
  • Moreover, the infection has been found to persist in animals intentionally infected for experimental purposes for several months.
  • The researchers further suggest that the circumstances and implications of the disease’s persistence in naturally infected animals are not well understood and require further investigation.

Cite This Article

APA
Engvall EO, Egenvall A. (2002). Granulocytic ehrlichiosis in Swedish dogs and horses. Int J Med Microbiol, 291 Suppl 33, 100-103. https://doi.org/10.1016/s1438-4221(02)80019-4

Publication

ISSN: 1438-4221
NlmUniqueID: 100898849
Country: Germany
Language: English
Volume: 291 Suppl 33
Pages: 100-103

Researcher Affiliations

Engvall, Eva Olsson
  • Eva.Olsson@sva.se
Egenvall, Agneta

    MeSH Terms

    • Animals
    • Dog Diseases / epidemiology
    • Dog Diseases / parasitology
    • Dogs
    • Ehrlichia / pathogenicity
    • Ehrlichiosis / epidemiology
    • Ehrlichiosis / parasitology
    • Ehrlichiosis / veterinary
    • Granulocytes / microbiology
    • Horse Diseases / epidemiology
    • Horse Diseases / parasitology
    • Horses
    • Serologic Tests / veterinary
    • Sweden / epidemiology

    Citations

    This article has been cited 6 times.
    1. Bogdan AM, Ionita M, Mitrea IL. Serological Evidence of Natural Exposure to Tick-Borne Pathogens in Horses, Romania. Microorganisms 2021 Feb 12;9(2).
      doi: 10.3390/microorganisms9020373pubmed: 33673353google scholar: lookup
    2. Khamesipour F, Dida GO, Anyona DN, Razavi SM, Rakhshandehroo E. Tick-borne zoonoses in the Order Rickettsiales and Legionellales in Iran: A systematic review. PLoS Negl Trop Dis 2018 Sep;12(9):e0006722.
      doi: 10.1371/journal.pntd.0006722pubmed: 30204754google scholar: lookup
    3. Giudice E, Giannetto C, Furco V, Alongi A, Torina A. Anaplasma phagocytophilum seroprevalence in equids: a survey in Sicily (Italy). Parasitol Res 2012 Aug;111(2):951-5.
      doi: 10.1007/s00436-012-2854-5pubmed: 22362364google scholar: lookup
    4. Heikkilä HM, Bondarenko A, Mihalkov A, Pfister K, Spillmann T. Anaplasma phagocytophilum infection in a domestic cat in Finland: Case report. Acta Vet Scand 2010 Nov 15;52(1):62.
      doi: 10.1186/1751-0147-52-62pubmed: 21078141google scholar: lookup
    5. Stuen S. Anaplasma phagocytophilum - the most widespread tick-borne infection in animals in Europe. Vet Res Commun 2007 Aug;31 Suppl 1:79-84.
      doi: 10.1007/s11259-007-0071-ypubmed: 17682851google scholar: lookup
    6. Probst J, Springer A, Fingerle V, Strube C. Frequency of Anaplasma phagocytophilum, Borrelia spp., and coinfections in Ixodes ricinus ticks collected from dogs and cats in Germany. Parasit Vectors 2024 Feb 23;17(1):87.
      doi: 10.1186/s13071-024-06193-wpubmed: 38395915google scholar: lookup