Hematology and hemostasis in the horse: normal functions and common abnormalities.
Abstract: In diseased animals, laboratory evaluations of erythrocytes, leukocytes, and hemostasis provide important information that contributes to either narrowing the list of potential diagnoses or to determining a specific diagnosis. To adequately interpret the results of these evaluations, normal erythrocyte and leukocyte kinetics and normal hemostatic function must be understood. In addition, knowledge of common diseases resulting in abnormalities of these laboratory tests and of typical changes in these tests caused by these diseases is vital. This article has reviewed normal erythrocyte and leukocyte kinetics and normal hemostatic functions that are clinically significant and has described the laboratory abnormalities expected in common diseases affecting these functions.
Publication Date: 1995-12-01 PubMed ID: 8925416DOI: 10.1016/s0749-0739(17)30306-1Google Scholar: Lookup
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Summary
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The research paper explores the normal functions of erythrocytes, leukocytes, and hemostatic process in horses, as well as common diseases impacting these functions and how they can be diagnosed through laboratory tests.
Understanding Erythrocyte and Leukocyte Kinetics and Hemostatic Function
- The study emphasizes the significance of understanding the normal function and kinetics of erythrocytes (red blood cells) and leukocytes (white blood cells) in order to interpret the results of laboratory evaluations correctly. Erythrocytes transport oxygen in the blood, while leukocytes function to fight off infections and diseases.
- In addition to this, comprehension of hemostasis, the process responsible to stop bleeding by maintaining the fluidity of the blood when necessary and clotting it during injuries, is vital. In order to diagnose abnormalities, a firm grasp of these normal functions is required.
Diagnostic Importance of Laboratory Evaluations
- The paper depicts the critical role of laboratory evaluations in diagnosing potential diseases in horses. Anomalies in blood elements or disorders in hemostasis can provide indispensable indications or completely determine a specific diagnosis in diseased animals.
- Different diseases result in varying abnormalities in these evaluations. Therefore, the laboratory tests provide an essential tool for veterinarians to either narrow down potential disease causes or reach a precise diagnosis.
Common Diseases and Their Impact
- The researchers review the common diseases affecting erythrocyte and leukocyte kinetics and the hemostatic function in horses. These diseases often cause perturbations in the normal functioning of these blood components and the hemostatic process, as noted in laboratory test results.
- It is fundamentally important to understand these typical changes indicated by diseases, as the changes act as crucial diagnostic tools. The abnormalities manifested in laboratory tests due to said diseases are directly linked to the functions they impact.
Cite This Article
APA
Lassen ED, Swardson CJ.
(1995).
Hematology and hemostasis in the horse: normal functions and common abnormalities.
Vet Clin North Am Equine Pract, 11(3), 351-389.
https://doi.org/10.1016/s0749-0739(17)30306-1 Publication
Researcher Affiliations
- Department of Pathology, Colorado State University, Fort Collins, USA.
MeSH Terms
- Aging / blood
- Anemia / blood
- Anemia / diagnosis
- Anemia / veterinary
- Animals
- Blood Coagulation / physiology
- Blood Platelets / pathology
- Breeding
- Erythrocytes / pathology
- Hemostasis / physiology
- Horse Diseases / blood
- Horses / blood
- Horses / genetics
- Horses / physiology
- Leukemia / blood
- Leukemia / veterinary
- Leukocytes / pathology
- Spleen / pathology
Citations
This article has been cited 4 times.- Massányi M, Halo M Jr, Massányi P, Mlyneková E, Greń A, Formicki G, Halo M. Changes in haematological and biochemical parameters in blood serum of horses during exposition to workload stress. Heliyon 2022 Dec;8(12):e12241.
- Chikhaoui M, Smail F, Adda F. Blood hematological values of Barb horses in Algeria. Open Vet J 2018;8(3):330-334.
- Brazil TJ, Dixon PM, Haslett C, Murray J, McGorum BC. Constitutive apoptosis in equine peripheral blood neutrophils in vitro. Vet J 2014 Dec;202(3):536-42.
- Sawesi OK, Elbaz AK, Mahmoud AS, Duro EM, Alteab AA, Milad KK, Bennuor EM. Hematological reference values of horses in Western Libya and their relationship to breed, age, and management. Open Vet J 2023 Dec;13(12):1696-1707.
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