Improved measurements of shear modulus and pleural membrane tension of the lung.
Abstract: The continuum solution for the deformation of an elastic half space covered by a membrane is used to interpret measurements of the indentation of lung lobes under a column of fluid. The shear modulus mu of the underlying parenchyma is found to be approximately 0.7 times transpulmonary pressure, independent of species size. The tension in the pleural membrane T increases rapidly with increasing membrane area. For dog lungs, the value of T is 10(3) to 10(4) dyn/cm. For the larger species tested, pigs and horses, T is larger. The continuum solution shows that a concentrated force applied to the pleural surface is distributed over a distance T/mu as it is transmitted across the pleural membrane. The membrane is important in determining the displacement produced by forces that act within a region that is small compared to this distance, approximately 2 cm for dog lungs. By comparing the tension-area curve of the pleural membrane with the pressure-volume curve of the lobe, it is found that the pleural membrane contributes about 20% of the work done by the lung during deflation.
Publication Date: 1979-07-01 PubMed ID: 468657DOI: 10.1152/jappl.1979.47.1.175Google Scholar: Lookup
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- Journal Article
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- U.S. Gov't
- P.H.S.
Summary
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The research paper presents an improved method of measuring the shear modulus and the pleural membrane tension of the lung, using a model of lung deformation under fluid pressure. The study shows that these measurements of lung elasticity and tension are crucial in understanding the lung’s deformation response and work contribution during deflation.
Shear Modulus
- The research discusses the interpretation of measurements of lung lobe indentation under fluid column pressure, primarily focusing on the shear modulus (mu) – a property of the underlying lung parenchyma tissue.
- The shear modulus represents how a material resists shear deformations (changes in shape without changes in volume). Higher values indicate stiffer materials.
- The findings suggest the shear modulus of lung parenchyma to be roughly 0.7 times the transpulmonary pressure, a measure of the force that helps extend the lung.
- This relationship holds across animal species and size, indicating a fundamental biomechanical feature of lung tissues.
Pleural Membrane Tension
- The study also provides novel insight into the tension (T) of the pleural membrane, the thin film that lines the lung’s outer surface and the chest’s inner surface.
- The tension increases rapidly with increasing membrane area. The larger the species (such as pigs and horses), the greater the tension found in the pleural membrane in comparison to smaller species like dogs.
- A force applied to the pleural surface spreads over a distance (T/mu). This shows the pleural membrane’s role in distributing forces acting on the lung and determining the displacement produced by these forces. In layman’s terms, it’s how the lung deforms under pressing forces.
Comparison of the Pleural Membrane and the Lung Lobe
- A key result of the research is the comparison between the tension-to-area ratio of the pleural membrane and the pressure-to-volume ratio of the lung lobe.
- It was found that the pleural membrane is responsible for about 20% of the work done by the whole lung during deflation. This could have significant implications for understanding various conditions like lung diseases and effects of invasive ventilation strategy.
Cite This Article
APA
Hajji MA, Wilson TA, Lai-Fook SJ.
(1979).
Improved measurements of shear modulus and pleural membrane tension of the lung.
J Appl Physiol Respir Environ Exerc Physiol, 47(1), 175-181.
https://doi.org/10.1152/jappl.1979.47.1.175 Publication
Researcher Affiliations
MeSH Terms
- Animals
- Biomechanical Phenomena
- Dogs
- Elasticity
- Horses
- In Vitro Techniques
- Lung / physiology
- Mathematics
- Models, Biological
- Pleura / physiology
- Swine
Citations
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