In vitro comparison of V-Loc™ versus Biosyn™ in a one-layer end-to-end anastomosis of equine jejunum.
Abstract: To compare a unidirectional barbed suture (V-Loc™) to its suture material equivalent (Biosyn™) in a single-layer end-to-end anastomosis of equine jejunum. Methods: Experimental in vitro study. Methods: Jejunal sections from adult horses (n = 5) without gastrointestinal disease. Methods: Jejunal end-to-end anastomoses (n = 9) were performed for each group (V-Loc™, Biosyn™) with a continuous Lembert pattern with an interruption every 120°. Anastomosis construction time, luminal diameter, and number of suture bites were recorded. Anastomosis constructs were distended with fluid at 1 L/min until failure. Location and intraluminal pressure at failure were recorded and all measurements were compared between groups. Results: V-Loc™ anastomoses were significantly faster to perform (13.1 ± 0.35 minutes) when compared to the Biosyn™ group (15.6 ± 0.72 minutes; P = .0004). No differences were observed for anastomotic index or number of suture bites. V-Loc™ anastomosis constructs had a significantly decreased bursting pressure (160 ± 11.6 mmHg) compared to Biosyn™ constructs (184 ± 16.9 mmHg; P = .01). Conclusions: V-Loc™ allowed faster construction time and did not cause a decreased anastomosis luminal diameter when compared with Biosyn™. V-Loc™ had a decreased bursting strength compared with Biosyn™, albeit well above pathologic pressures encountered clinically. Use of V-Loc™ may be beneficial for decreasing the amount of exposed suture material because of the absence of knots after construction and has the potential to result in decreased adhesions.
© Copyright 2013 by The American College of Veterinary Surgeons.
Publication Date: 2013-11-20 PubMed ID: 24256315DOI: 10.1111/j.1532-950X.2013.12081.xGoogle Scholar: Lookup
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- Comparative Study
- Journal Article
- Adult Horses
- Anatomy
- Animal Studies
- Cadaver Study
- Clinical Study
- Clinical Symptoms
- Comparative Study
- Diagnostic Technique
- Disease Treatment
- Equine Diseases
- Equine Health
- Experimental Methods
- Gastrointestinal Diseases
- Gastrointestinal Health
- Horses
- In Vitro Research
- Surgery
- Suture
- Veterinary Medicine
- Veterinary Procedure
Summary
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The research studies the comparison between two types of sutures, V-Loc™ and Biosyn™, in end-to-end stitching of horse intestines. The study found that while V-Loc™ sutures allowed faster suturing time without compromising luminal diameter, they had a slightly lower burst strength than Biosyn™.
Objective of the Research
- The primary objective of this research was to compare the efficacy and efficiency of V-Loc™, a unidirectional barbed suture material, with the Biosyn™ suture in a one-layer end-to-end anastomosis (the surgical joining of two parts) of equine jejunum (part of horse intestines).
Methods of the Study
- Jejunal sections from five adult horses without any gastrointestinal disease were used in this experimental in vitro study.
- End-to-end anastomoses were performed on nine different sections, each for two groups (V-Loc™ and Biosyn™), using a continuous Lembert pattern with an interruption every 120°.
- Anastomosis construction time, luminal diameter, and the number of suture bites were thoroughly documented.
- The anastomosis constructs were thereafter filled with fluid at a rate of 1 L/min until failure, upon which the location and intraluminal pressure at failure were recorded.
Results of the Research
- The research discovered that the construction of anastomoses with V-Loc™ sutures was significantly faster (13.1 ± 0.35 minutes) compared to the Biosyn™ group (15.6 ± 0.72 minutes).
- No observable difference was found in the anastomotic index or the number of suture bites between the two groups.
- However, V-Loc™ sutures showed a significantly lower bursting pressure (160 ± 11.6 mmHg) compared to Biosyn™ sutures (184 ± 16.9 mmHg).
Conclusions of the Research
- Even though V-Loc™ proved to offer a faster construction time and did not affect the anastomosis luminal diameter when compared with Biosyn™, the bursting strength of V-Loc™ sutures was comparatively less.
- The bursting strength, despite being lower, was still well above the problematic pressures typically encountered clinically.
- The study concludes that using V-Loc™ could be beneficial in reducing the amount of exposed suture material due to the absence of knots after construction. This feature might also result in less adhesion.
Cite This Article
APA
Nelson BB, Hassel DM.
(2013).
In vitro comparison of V-Loc™ versus Biosyn™ in a one-layer end-to-end anastomosis of equine jejunum.
Vet Surg, 43(1), 80-84.
https://doi.org/10.1111/j.1532-950X.2013.12081.x Publication
Researcher Affiliations
- Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado.
MeSH Terms
- Anastomosis, Surgical / instrumentation
- Anastomosis, Surgical / methods
- Anastomosis, Surgical / veterinary
- Animals
- Dioxanes
- Horses / surgery
- In Vitro Techniques
- Jejunum / surgery
- Polymers
- Sutures / standards
- Sutures / veterinary
- Tensile Strength
Citations
This article has been cited 8 times.- Duffy DJ, Chang YJ, Moore GE. Influence of barbed suture oversew of the transverse staple line during functional end-to-end stapled anastomosis in a canine jejunal enterectomy model.. Vet Surg 2022 Jul;51(5):801-808.
- Sarkisian NW, Mulon PY. Comparison between barbed and conventional sutures for longitudinal thelotomy closure in an ex-vivo bovine model.. Can Vet J 2022 May;63(5):535-539.
- Lenoir A, Perrin BRM, Lepage OM. Ex Vivo Comparison of a UV-Polymerizable Methacrylate Adhesive versus an Inverting Pattern as the Second Layer of a Two-Layer Hand-Sewn Jejunal Anastomosis in Horses: A Pilot Study.. Vet Med Int 2021;2021:5545758.
- Averay K, van Galen G, Ward M, Verwilghen D. Effect of three different needle holders on gastrointestinal anastomosis construction time and bursting pressure in equine jejunal segments.. BMC Vet Res 2021 Apr 15;17(1):167.
- Adler DMT, Østergaard S, Jørgensen E, Jacobsen S. Bidirectional knotless barbed versus conventional smooth suture for closure of surgical wounds in inguinal castration in horses.. BMC Vet Res 2020 Jul 17;16(1):250.
- Giusto G, Iussich S, Tursi M, Perona G, Gandini M. Comparison of two different barbed suture materials for end-to-end jejuno-jejunal anastomosis in pigs.. Acta Vet Scand 2019 Jan 5;61(1):3.
- Tsukada T, Kaji M, Kinoshita J, Shimizu K. Use of Barbed Sutures in Laparoscopic Gastrointestinal Single-Layer Sutures.. JSLS 2016 Jul-Sep;20(3).
- Ferrer-Márquez M, Belda-Lozano R, Soriano-Maldonado A. Use of Barbed Sutures in Bariatric Surgery. Review of the Literature.. Obes Surg 2016 Aug;26(8):1964-9.
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