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Home / Equine Research Bank / Vet Surg / Incisional complications after skin closure with n-butyl cya...
Veterinary surgery : VS2020; 50(1); 186-195; doi: 10.1111/vsu.13534

Incisional complications after skin closure with n-butyl cyanoacrylate or stainless-steel skin staples in horses undergoing colic surgery.

Abstract: To compare the prevalence of incisional complications after skin closure with n-butyl cyanoacrylate (NBC) or stainless-steel skin staples (SS) after ventral midline celiotomy for colic surgery in the horse. Methods: Retrospective study (2014-2018). Methods: Two hundred eighteen horses. Methods: Medical records of horses that underwent exploratory celiotomy for colic were included when the skin was closed with NBC or SS and the horse survived ≥15 days after surgery. Records and a follow-up questionnaire were used to determine in-hospital and posthospital discharge incisional complications. Associations between variables were assessed by using bivariable and multivariable analysis. Results: The cutaneous incision was closed with SS in 113 of 218 (51.8%) horses and with NBC in 105 of 218 (48.2%) horses. Follow-up information was available in 166 of 218 horses. Five horses with incisional complications prior to discharge but without follow-up were included in the overall analysis. Incisional complications were recorded in 17.5% (30/171) of horses, including 19.1% (17/89) of closures with SS and 15.9% (12/82) of closures with NBC (P = .54). Complications occurred before discharge in 14 of 218 (6.4%) horses and after discharge in 16 of 166 (9.6%) horses. Four horses with in-hospital incisional complications (surgical site infection) developed a second complication after discharge (hernia). Packed cell volume was a risk factor for in-hospital incisional complications (P = .04), and in-hospital incisional complications were associated with posthospital discharge incisional complications (P = .01). Conclusions: Occurrence of incisional complications did not differ between NBC and SS. Conclusions: N-butyl cyanoacrylate is a suitable alternative to SS to close the cutaneous incision for ventral midline celiotomy for colic surgery in the horse.
© 2020 American College of Veterinary Surgeons.
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Publication Date: 2020-10-27 PubMed ID: 33107618DOI: 10.1111/vsu.13534Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research looks into the impact of two different skin closure methods, n-butyl cyanoacrylate (NBC) and stainless-steel staples (SS), on the incidence of incisional complications in horses that have undergone colic surgery. The study concludes that there is no significant difference in the occurrence of these complications between the two methods, suggesting that NBC could be a viable alternative to SS for this particular surgical procedure.

Research Methods

  • The authors conducted a retrospective study, looking back at medical records from 2014 to 2018 of horses that underwent an exploratory celiotomy for colic – a type of abdominal surgery.
  • The study only included those horses where the skin was closed with either NBC or SS and the horse survived for at least 15 days post-surgery. This was to ensure that any recorded complications were likely related to the surgery and not other health issues.
  • Both in-hospital and post-hospital discharge incisional complications were recorded using the medical records and follow-up questionnaires.
  • The associations between variables, such as the type of closure used and the occurrence of complications, were assessed using bivariable and multivariable analysis.

Research Findings

  • The skin incision was closed with SS in 113 out of 218 horses (or 51.8%), and with NBC in 105 out of 218 horses (48.2%).
  • Incisional complications occurred in 17.5% (30 out of 171) of the horses, with a slightly higher occurrence in the SS group (19.1% or 17 out of 89) compared to the NBC group (15.9% or 12 out of 82).
  • Complications arose both before discharge (in 6.4% of horses) and after discharge (in 9.6% of horses).
  • Four horses that had in-hospital incisional complications (specifically, a surgical site infection) developed a second complication (a hernia) after discharge.
  • A higher packed cell volume was found to be a risk factor for in-hospital incisional complications, and an occurrence of in-hospital incisional complications was associated with post-discharge complications.

Research Conclusions

  • No significant difference was found between the NBC and SS closure methods in terms of the occurrence of incisional complications. Therefore, NBC can be considered a viable alternative to staples for ventral midline celiotomy for colic surgery in horses.

Cite This Article

APA
Martinez-Lopez J, Brown JA, Werre SR. (2020). Incisional complications after skin closure with n-butyl cyanoacrylate or stainless-steel skin staples in horses undergoing colic surgery. Vet Surg, 50(1), 186-195. https://doi.org/10.1111/vsu.13534

Publication

Veterinary surgery : VS
ISSN: 1532-950X
NlmUniqueID: 8113214
Country: United States
Language: English
Volume: 50
Issue: 1
Pages: 186-195

Researcher Affiliations

Martinez-Lopez, Javier
  • Department of Large Animal Clinical Sciences, Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, Virginia.
Brown, James A
  • Department of Large Animal Clinical Sciences, Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, Virginia.
Werre, Stephen R
  • Population Health Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Population Health Sciences, Blacksburg, Virginia.

MeSH Terms

  • Animals
  • Colic / surgery
  • Colic / veterinary
  • Colon / surgery
  • Enbucrilate / pharmacology
  • Female
  • Horse Diseases / surgery
  • Horses
  • Male
  • Postoperative Complications / veterinary
  • Retrospective Studies
  • Stainless Steel
  • Surgical Wound / complications
  • Surgical Wound / veterinary
  • Sutures / veterinary
  • Tissue Adhesives / pharmacology

References

This article includes 35 references
  1. Dukti S, White N. Surgical complications of colic surgery.. Vet Clin North Am Equine Pract 2008;24(3):515-534. vii-viii.
  2. Tnibar A, Grubbe Lin K, Thuroe Nielsen K. Effect of a stent bandage on the likelihood of incisional infection following exploratory coeliotomy for colic in horses: a comparative retrospective study.. Equine Vet J 2013;45(5):564-569.
  3. Durward-Akhurst SA, Mair TS, Boston R, Dunkel B. Comparison of two antimicrobial regimens on the prevalence of incisional infections after colic surgery.. Vet Rec 2013;172(11):287.
  4. Klohnen A, Biedrzycki A. A new approach to the detection of incisional site infections in horses after colic surgery.. Proceedings of the 48th British Equine Veterinary Association Congress September 9-12, 2009; Birmingham, United Kingdom.
  5. Isgren CM, Salem SE, Townsend NB, Timofte D, Maddox TW, Archer DC. Sequential bacterial sampling of the midline incision in horses undergoing exploratory laparotomy.. Equine Vet J 2019;51(1):38-44.
  6. Kilcoyne I, Dechant JE, Kass PH, Nieto JE. Evaluation of the risk of incisional infection in horses following application of protective dressings after exploratory celiotomy for treatment of colic.. J Am Vet Med Assoc 2019;254(12):1441-1447.
  7. Anderson SL, Devick I, Bracamonte JL. Occurrence of incisional complications after closure of equine celiotomies with USP 7 polydioxanone.. Vet Surg 2015;44(4):521-526.
  8. Coomer RP, Mair TS, Edwards GB, Proudman CJ. Do subcutaneous sutures increase risk of laparotomy wound suppuration?. Equine Vet J 2007;39(5):396-399.
  9. Torfs S, Levet T, Delesalle C. Risk factors for incisional complications after exploratory celiotomy in horses: do skin staples increase the risk?. Vet Surg 2010;39(5):616-620.
  10. Smith TO, Sexton D, Mann C, Donell S. Sutures versus staples for skin closure in orthopaedic surgery: meta-analysis.. BMJ 2010;340:c1199.
  11. Martín-Ballester A, García-Cerdá D, Prieto-Moure B, Martín-Martínez JM, Lloris-Carsí JM. Use of cyanoacrylate adhesives in dermal lesions: a review.. J Adhesion Sci Technol 2013;28(6):573-597.
  12. Singer AJ, Quinn JV, Hollander JE. The cyanoacrylate topical skin adhesives.. Am J Emerg Med 2008;26(4):490-496.
  13. Coulthard P, Worthington H, Esposito M, Van der Elst M, Van Waes OJF. Tissue adhesives for closure of sugical incisions (review).. Clin Otolaryngol 2006;31(6):538-538.
  14. Ando M, Tamaki T, Yoshida M. Surgical site infection in spinal surgery: a comparative study between 2-octyl-cyanoacrylate and staples for wound closure.. Eur Spine J 2014;23(4):854-862.
  15. Eggers MD, Fang L, Lionberger DR. A comparison of wound closure techniques for total knee arthroplasty.. J Arthroplasty 2011;26(8):1251-1258.
  16. Kitshoff AM, Louwagie J, Or M. Biomechanical properties of celiotomy wounds closed with tape and cyanoacrylate versus intradermal sutures.. Vet Surg 2018;47(8):1087-1093.
  17. Quinn J. Clinical approaches to the use of cyanoacrylate tissue adhesives.. Tissue Adhesives Clin Med 2005;27-76.
  18. Mertz PM, Davis SC, Cazzaniga AL, Drosou A, Eaglstein WH. Barrier and antibacterial properties of 2-octyl cyanoacrylate-derived wound treatment films.. J Cutan Med Surg 2003;7(1):1-6.
  19. Silvestri A, Brandi C, Grimaldi L. Octyl-2-cyanoacrylate adhesive for skin closure and prevention of infection in plastic surgery.. Aesthetic Plast Surg 2006;30(6):695-699.
  20. Isgren CM, Salem SE, Archer DC, Worsman FC, Townsend NB. Risk factors for surgical site infection following laparotomy: effect of season and perioperative variables and reporting of bacterial isolates in 287 horses.. Equine Vet J 2017;49(1):39-44.
  21. Mair TS, Smith LJ. Survival and complication rates in 300 horses undergoing surgical treatment of colic. Part 2: short-term complications.. Equine Vet J 2005;37(4):303-309.
  22. Roy MF, Kwong GP, Lambert J, Massie S, Lockhart S. Prognostic value and development of a scoring system in horses with systemic inflammatory response syndrome.. J Vet Intern Med 2017;31(2):582-592.
  23. Watanabe A, Kohnoe S, Shimabukuro R. Risk factors associated with surgical site infection in upper and lower gastrointestinal surgery.. Surg Today 2008;38(5):404-412.
  24. Wilson DA, Baker GJ, Boero MJ. Complications of celiotomy incisions in horses.. Vet Surg 1995;24(6):506-514.
  25. Chow A, Marshall H, Zacharakis E, Paraskeva P, Purkayastha S. Use of tissue glue for surgical incision closure: a systematic review and meta-analysis of randomized controlled trials.. J Am Coll Surg 2010;211(1):114-125.
  26. French NP, Smith J, Edwards GB, Proudman CJ. Equine surgical colic: risk factors for postoperative complications.. Equine Vet J 2002;34(5):444-449.
  27. Smith LJ, Mellor DJ, Marr CM, Reid SW, Mair TS. Incisional complications following exploratory celiotomy: does an abdominal bandage reduce the risk?. Equine Vet J 2007;39(3):277-283.
  28. Ingle-Fehr JE, Baxter GM, Howard RD, Trotter GW, Stashak TS. Bacterial culturing of ventral median celiotomies for prediction of postoperative incisional complications in horses.. Vet Surg 1997;26(1):7-13.
  29. Prince D, Solanki Z, Varughese R, Mastej J, Prince D. Antibacterial effect and proposed mechanism of action of a topical surgical adhesive.. Am J Infect Control 2018;46(1):26-29.
  30. Scharner D, Gittel C, Winter K. Comparison of incisional complications between skin closures using a simple continuous or intradermal pattern: a pilot study in horses undergoing ventral median celiotomy.. Peer J 2018;6:e5772.
  31. Colbath AC, Patipa L, Berghaus RD, Parks AH. The influence of suture pattern on the incidence of incisional drainage following exploratory laparotomy.. Equine Vet J 2014;46(2):156-160.
  32. Aristizabal FA, Lopes MA, Silva A, Avanza MF, Nieto JE. Evaluation of the effect of onlay mesenteric flaps on end-to-end jejunojejunostomy healing in horses.. Vet Surg 2014;43(4):479-486.
  33. Freeman LJ, Pettit GD, Robinette JD, Lincoln JD, Person MW. Tissue reaction to suture material in the feline linea alba. A retrospective, prospective, and histologic study.. Vet Surg 1987;16(6):440-445.
  34. Gazivoda D, Pelemis D, Vujaskovic G, Djurdjevic S. Influence of suturing material on wound healing-an experimental study on dogs.. Vojnosanit Pregl 2015;72(5):397-404.
  35. Darnaud SJ, Southwood LL, Aceto HW, Stefanovski D, Tomassone L, Zarucco L. Are horse age and incision length associated with surgical site infection following equine colic surgery?. Vet J 2016;217:3-7.

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