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Transboundary and emerging diseases2014; 60 Suppl 2; 45-50; doi: 10.1111/tbed.12141

Indigenous West Nile virus infections in horses in Albania.

Abstract: Serum samples collected from 167 equines of 12 districts in Albania were tested for West Nile virus-specific antibodies by enzyme-linked immunosorbent assay and virus neutralization assay, using WNV lineage 1 and 2. In addition, 95 bird serum samples from Albania and 29 horse samples from Kosovo were tested in ELISA. An overall seroprevalence rate of 22% was found in horses from Albania, whereas no specific antibodies were found in the equine samples from Kosovo and the bird samples. This is the first report indicating WNV infections in animals in Albania, and the first reported seroprevalence study conducted for Kosovo. These results provide evidence for widespread infections of WNV in Albania.
Publication Date: 2014-03-05 PubMed ID: 24589101DOI: 10.1111/tbed.12141Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research paper discusses the detection of the West Nile Virus (WNV) in horses from various districts in Albania, with a significant prevalence rate, as well as the absence of the WNV in horses and birds examined in Kosovo.

Methodology & Samples

  • The research used samples acquired from 167 horses across 12 districts in Albania. In addition to this primary set of samples, 95 bird serum samples from Albania and 29 horse samples from Kosovo were also used.
  • The study employed techniques like enzyme-linked immunosorbent assay (ELISA) and virus neutralization assays. These techniques can detect the presence of WNV-specific antibodies in the specimens, which signify an immune response to a past or recent infection with the virus.

Findings from Albania

  • The result of the Albanian samples indicated a 22% seroprevalence rate amongst horses, marking the presence of WNV in these horses. Seroprevalence refers to the total number of individuals in a population who test positive for a specific disease based on serology (blood serum) specimens. This means approximately 22% of horses sampled in Albania had WNV-specific antibodies, indicating prior exposure to the infection.

Findings from Kosovo

  • In contrast, no specific WNV antibodies were discovered within samples gathered from both Kosovo’s horses or birds. This absence suggests that, these animals had not been exposed to the West Nile Virus.

Significance of the Study

  • This study is crucial as it is the first of its kind to indicate WNV infection among animals in Albania, and it provided the first-ever seroprevalence report from Kosovo.
  • The evidence of widespread WNV in Albania underscores potential public health risks given that the virus can be transmitted to humans via the bites of infected mosquitoes. Preventive measures to control the disease’s transmission could thus be necessary.

Cite This Article

APA
Berxholi K, Ziegler U, Rexhepi A, Schmidt K, Mertens M, Korro K, Cuko A, Angenvoort J, Groschup MH. (2014). Indigenous West Nile virus infections in horses in Albania. Transbound Emerg Dis, 60 Suppl 2, 45-50. https://doi.org/10.1111/tbed.12141

Publication

ISSN: 1865-1682
NlmUniqueID: 101319538
Country: Germany
Language: English
Volume: 60 Suppl 2
Pages: 45-50

Researcher Affiliations

Berxholi, K
  • Faculty of Veterinary Medicine in Tirana, Tirana, Albania.
Ziegler, U
    Rexhepi, A
      Schmidt, K
        Mertens, M
          Korro, K
            Cuko, A
              Angenvoort, J
                Groschup, M H

                  MeSH Terms

                  • Albania / epidemiology
                  • Animals
                  • Antibodies, Viral / blood
                  • Antibodies, Viral / immunology
                  • Enzyme-Linked Immunosorbent Assay
                  • Horse Diseases / epidemiology
                  • Horse Diseases / transmission
                  • Horse Diseases / virology
                  • Horses / virology
                  • Seroepidemiologic Studies
                  • West Nile Fever / epidemiology
                  • West Nile Fever / veterinary
                  • West Nile Fever / virology
                  • West Nile virus / immunology

                  Citations

                  This article has been cited 6 times.
                  1. Gothe LMR, Ganzenberg S, Ziegler U, Obiegala A, Lohmann KL, Sieg M, Vahlenkamp TW, Groschup MH, Hörügel U, Pfeffer M. Horses as Sentinels for the Circulation of Flaviviruses in Eastern-Central Germany. Viruses 2023 Apr 30;15(5).
                    doi: 10.3390/v15051108pubmed: 37243194google scholar: lookup
                  2. Vilibic-Cavlek T, Savic V, Petrovic T, Toplak I, Barbic L, Petric D, Tabain I, Hrnjakovic-Cvjetkovic I, Bogdanic M, Klobucar A, Mrzljak A, Stevanovic V, Dinjar-Kujundzic P, Radmanic L, Monaco F, Listes E, Savini G. Emerging Trends in the Epidemiology of West Nile and Usutu Virus Infections in Southern Europe. Front Vet Sci 2019;6:437.
                    doi: 10.3389/fvets.2019.00437pubmed: 31867347google scholar: lookup
                  3. Di Sabatino D, Bruno R, Sauro F, Danzetta ML, Cito F, Iannetti S, Narcisi V, De Massis F, Calistri P. Epidemiology of West Nile disease in Europe and in the Mediterranean Basin from 2009 to 2013. Biomed Res Int 2014;2014:907852.
                    doi: 10.1155/2014/907852pubmed: 25302311google scholar: lookup
                  4. Hoxha I, Dervović J, Unterköfler MS, Schlamadinger L, Situmorang T, Fuehrer HP, Obwaller AG, Sekulin K, Camp JV, Harl J, Walochnik J, Alić A, Kniha E. A cross section through mosquitoes of Bosnia and Herzegovina: Barcodes, blood meals and pathogens. One Health 2025 Dec;21:101246.
                    doi: 10.1016/j.onehlt.2025.101246pubmed: 41159105google scholar: lookup
                  5. Hoxha I, Xhekaj B, Muja-Bajraktari N, Sekulin K, Unterköfler MS, Schlamadinger L, Situmorang T, Fuehrer HP, Obwaller AG, Camp JV, Walochnik J, Sherifi K, Kniha E. First Detection of West Nile Virus (WNV) Lineage 2 in Mosquitoes in the Republic of Kosovo. Transbound Emerg Dis 2025;2025:3208806.
                    doi: 10.1155/tbed/3208806pubmed: 40599430google scholar: lookup
                  6. Emmerich P, Jakupi X, Sherifi K, Dreshaj S, Kalaveshi A, Hemmer C, Hajdari DP, von Possel R, Cadar D, Tomazatos A. Serologic and Genomic Investigation of West Nile Virus in Kosovo. Viruses 2023 Dec 30;16(1).
                    doi: 10.3390/v16010066pubmed: 38257766google scholar: lookup