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Emerging infectious diseases2016; 22(7); 1242-1245; doi: 10.3201/eid2207.151636

Infection with Possible Novel Parapoxvirus in Horse, Finland, 2013.

Abstract: A horse in Finland exhibited generalized granulomatous inflammation and severe proliferative dermatitis. After euthanization, we detected poxvirus DNA from a skin lesion sample. The virus sequence grouped with parapoxviruses, closely resembling a novel poxvirus detected in humans in the United States after horse contact. Our findings indicate horses may be a reservoir for zoonotic parapoxvirus.
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Publication Date: 2016-06-18 PubMed ID: 27315302PubMed Central: PMC4918186DOI: 10.3201/eid2207.151636Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study recounts a case of a horse in Finland, afflicted by an uncommon inflammatory condition and severe skin disorder, diagnosed with a potentially new variety of Parapoxvirus. The findings suggest that horses may act as hosts to this type of zoonotic parapoxvirus which could potentially infect humans.

Overview of the Study

  • The research focused on a unique case, where a horse in Finland was observed to have generalized granulomatous inflammation (inflammatory nodules) and severe proliferative dermatitis (skin disorder).
  • To understand the cause behind these unusual symptoms, the horse was euthanized and skin lesion samples were analyzed.

Detection of Parapoxvirus

  • Through these samples, DNA of a poxvirus, a class of viruses known to cause skin lesions, was detected.
  • Interestingly, the sequence of the detected virus correlated with parapoxviruses, suggesting that the horse was affected by a parapoxvirus strain.
  • Parapoxviruses are responsible for causing skin infections in host species and can occasionally infect humans as well (zoonotic parapoxvirus). They typically do not cause severe illness in humans but can lead to skin lesions.

Association with a Novel Poxvirus

  • What made this virus particularly interesting was its close resemblance to a new variant of poxvirus detected in humans in the United States.
  • This novel virus was also identified in humans after contact with a horse, thereby drawing a consequential link.

Implications of the Study

  • The research concludes that horses may act as reservoirs for this zoonotic parapoxvirus. That is, horses could potentially harbor the virus without apparent illness and transfer it to humans upon contact.
  • This highlights the need for more studies on the novel parapoxvirus strain and its zoonotic potential to better understand its occurrence, transmission, and effects.

Cite This Article

APA
Airas N, Hautaniemi M, Syrjä P, Knuuttila A, Putkuri N, Coulter L, McInnes CJ, Vapalahti O, Huovilainen A, Kinnunen PM. (2016). Infection with Possible Novel Parapoxvirus in Horse, Finland, 2013. Emerg Infect Dis, 22(7), 1242-1245. https://doi.org/10.3201/eid2207.151636

Publication

Emerging infectious diseases
ISSN: 1080-6059
NlmUniqueID: 9508155
Country: United States
Language: English
Volume: 22
Issue: 7
Pages: 1242-1245

Researcher Affiliations

Airas, Niina
    Hautaniemi, Maria
      Syrjä, Pernilla
        Knuuttila, Anna
          Putkuri, Niina
            Coulter, Lesley
              McInnes, Colin J
                Vapalahti, Olli
                  Huovilainen, Anita
                    Kinnunen, Paula M

                      MeSH Terms

                      • Animals
                      • Finland / epidemiology
                      • Horse Diseases / epidemiology
                      • Horse Diseases / virology
                      • Horses
                      • Male
                      • Parapoxvirus / classification
                      • Parapoxvirus / genetics
                      • Phylogeny
                      • Poxviridae Infections / epidemiology
                      • Poxviridae Infections / veterinary
                      • Poxviridae Infections / virology
                      • Zoonoses

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                      Citations

                      This article has been cited 7 times.
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