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The Veterinary clinics of North America. Equine practice1995; 11(3); 391-414; doi: 10.1016/s0749-0739(17)30307-3

Interpretation of equine serum biochemical profile results.

Abstract: A serum biochemical profile is a group of chemical assays that are used to analyze biochemical constituents of serum. Interpretation of the results requires an understanding of what is actually measured by an assay and knowledge of the pathophysiologic conditions that occur in animals. Interpretative information is presented for the following serum analytes: urea, creatinine, glucose, total protein, albumin, globulins, calcium, phosphorus, magnesium, iron, bilirubin, cholesterol, triglyceride, sodium, potassium, chloride, total carbon dioxide content, aspartate transaminase, lactate dehydrogenase, alanine transaminase, alkaline phosphatase, γ-glutamyltransferase, creatine kinase, amylase, and lipase.
Publication Date: 1995-12-01 PubMed ID: 8925417DOI: 10.1016/s0749-0739(17)30307-3Google Scholar: Lookup
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Summary

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This research paper focuses on interpreting the results of a serum biochemical profile in horses, which involves the chemical analysis of a horse’s serum to understand its health status. The paper presents interpretation guidelines for a wide range of serum analytes, offering insights into pathophysiologic conditions that can manifest in horses.

Understanding the Serum Biochemical Profile

  • A serum biochemical profile is a collection of chemical tests conducted on the serum—a clear, yellowish fluid that remains after blood clotting—to assess the components and their levels.
  • These tests are vital for medical diagnosis, as they provide a snapshot of the organism’s metabolic status, signifying the presence or absence of certain diseases.
  • The study emphasizes that proper interpretation of these results necessitates understanding what each assay measures and the pathophysiologic conditions prevalent in animals.

The Serum Analytes

  • The scope of the study covers a broad range of serum analytes, including urea, creatinine, glucose, total protein, and many others.
  • These analytes are essentially substances analyzed in the biochemistry lab. For instance, high urea levels could indicate a problem with kidney function, while abnormal glucose levels may signal diabetes.
  • Other discussed constituents are minerals like sodium, potassium, and iron that play crucial roles in various biological functions.

Interpretation of Data

  • The core of this study presents the interpretation of these measurements, thereby providing a practical guide to veterinarians and other practitioners who conduct lab tests on horses.
  • Each analyte’s interpretation involves comprehending its normal range, being aware of its function in the body, and understanding how its abnormal levels can influence a horse’s health.
  • For example, the interpretation of aspartate transaminase—a liver enzyme—would require knowledge about liver function and diseases in horses.

Cite This Article

APA
Stockham SL. (1995). Interpretation of equine serum biochemical profile results. Vet Clin North Am Equine Pract, 11(3), 391-414. https://doi.org/10.1016/s0749-0739(17)30307-3

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 11
Issue: 3
Pages: 391-414

Researcher Affiliations

Stockham, S L
  • Department of Veterinary Pathobiology, University of Missouri-Columbia, USA.

MeSH Terms

  • Animals
  • Blood Chemical Analysis / standards
  • Blood Chemical Analysis / veterinary
  • Blood Proteins / analysis
  • Creatinine / blood
  • Electrolytes / blood
  • Enzymes / blood
  • Horse Diseases / blood
  • Horse Diseases / diagnosis
  • Horses / blood
  • Minerals / blood
  • Reference Standards
  • Urea / blood

Citations

This article has been cited 8 times.
  1. Huertas RM, Arguedas M, Estrada JM, Moscoso E, Umaña D, Solano G, Vargas M, Segura Á, Sánchez A, Herrera M, Villalta M, Arroyo-Portilla C, Gutiérrez JM, León G. Clinical effects of immunization, bleeding, and albumin-based fluid therapy in horses used as immunoglobulin source to produce a polyspecific antivenom (Echitab-plus-ICP) towards venoms of African snakes. Toxicon X 2023 Jun;18:100158.
    doi: 10.1016/j.toxcx.2023.100158pubmed: 37180815google scholar: lookup
  2. Lee H, Lee A, Seo N, Oh J, Kweon OK, An HJ, Kim J. Discovery of N-glycan Biomarkers for the Canine Osteoarthritis. Life (Basel) 2020 Sep 14;10(9).
    doi: 10.3390/life10090199pubmed: 32937769google scholar: lookup
  3. Takasu M, Nagatani N, Tozaki T, Kakoi H, Maeda M, Murase T, Mukoyama H. Hematological and biochemical reference values for the endangered kiso horse. J Equine Sci 2013;24(4):75-8.
    doi: 10.1294/jes.24.75pubmed: 24834006google scholar: lookup
  4. Alberghina D, Casella S, Giannetto C, Marafioti S, Piccione G. Effect of storage time and temperature on the total protein concentration and electrophoretic fractions in equine serum. Can J Vet Res 2013 Oct;77(4):293-6.
    pubmed: 24124272
  5. Moore RM, Muir WW, Rush BR. Systemic and colonic venous plasma biochemical alterations in horses during low-flow ischemia and reperfusion of the large colon. Can J Vet Res 1998 Jan;62(1):14-20.
    pubmed: 9442934
  6. Maier I, Kienzle E. A Meta-Analysis on Quantitative Sodium, Potassium and Chloride Metabolism in Horses and Ponies. Animals (Basel) 2025 Jan 13;15(2).
    doi: 10.3390/ani15020191pubmed: 39858191google scholar: lookup
  7. Ding J, Gu B, Meng J, Hu M, Wang W, Liu J. Response of serum biochemical profile, antioxidant enzymes, and gut microbiota to dietary Hong-bailanshen supplementation in horses. Front Microbiol 2024;15:1327210.
    doi: 10.3389/fmicb.2024.1327210pubmed: 38444806google scholar: lookup
  8. Lacerenza MD, Arantes JA, Reginato GM, Passarelli D, Balieiro JCC, Amaral AR, Vendramini THA, Brunetto MA, Dória RGS. Effects of β-Glucan Supplementation on LPS-Induced Endotoxemia in Horses. Animals (Basel) 2024 Jan 31;14(3).
    doi: 10.3390/ani14030474pubmed: 38338117google scholar: lookup