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Antimicrobial agents and chemotherapy1981; 19(2); 355-356; doi: 10.1128/AAC.19.2.355

Isolation of antibiotic-resistant Salmonella krefeld from clinical veterinary materials.

Abstract: Six isolations of Salmonella krefeld were made from clinical veterinary specimens. These isolates were multiply resistant to several antimicrobial agents commonly used to treat salmonellosis.
Publication Date: 1981-02-01 PubMed ID: 7347567PubMed Central: PMC181429DOI: 10.1128/AAC.19.2.355Google Scholar: Lookup
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  • Journal Article

Summary

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The research is about isolating an antibiotic-resistant strain of Salmonella krefeld obtained from clinical veterinary samples.

Overview of the Research

In the process of investigating the occurrence and distribution of antibiotic resistance in Salmonella strains, the researchers isolated the bacteria Salmonella krefeld from different veterinary specimens. These bacterial isolates displayed a high level of resistance against multiple antibiotics commonly employed in the treatment of salmonellosis, an infection caused by Salmonella bacteria.

Isolation of Salmonella krefeld

The methodology of isolation was not detailed in the abstract, but it typically involves:

  • Collection of samples from possibly infected animals or from their environment.
  • Placing these samples into a selective growth media where the bacteria can proliferate.
  • Isolating individual colonies of the bacterium for further analysis and identification.

Antibiotic Resistance of the Isolates

The Salmonella krefeld isolated in this study showed resistance to multiple antibiotics. Details about the specific antibiotics or the reasons for the resistance were not mentioned in the abstract. However, some common reasons for bacterial antibiotic resistance include:

  • Mutations in the bacterial genome that result in resistance to the drug’s action.
  • The ability of the bacterium to inactivate or eliminate the antibiotic before it can do any harm.
  • The presence of plasmids, small circular DNA segments, that carry antibiotic resistance genes and can be transferred between bacteria.

Implications of the Findings

The implications of this study’s findings are significant:

  • The presence of antibiotic-resistant strains of Salmonella in animals could pose severe health risks if they were to infect humans.
  • Learning about antibiotic resistance in these strains helps in tailoring more effective treatment strategies in both veterinary and human medicine.
  • The study emphasizes the necessity for continuous monitoring of antibiotic resistance in Salmonella strains in the veterinary setting to avoid potential future health crises.

Cite This Article

APA
Mathewson JJ, Simpson RB, Roush DA. (1981). Isolation of antibiotic-resistant Salmonella krefeld from clinical veterinary materials. Antimicrob Agents Chemother, 19(2), 355-356. https://doi.org/10.1128/AAC.19.2.355

Publication

ISSN: 0066-4804
NlmUniqueID: 0315061
Country: United States
Language: English
Volume: 19
Issue: 2
Pages: 355-356

Researcher Affiliations

Mathewson, J J
    Simpson, R B
      Roush, D A

        MeSH Terms

        • Animals
        • Anti-Bacterial Agents / pharmacology
        • Cat Diseases / microbiology
        • Cats
        • Cattle
        • Cattle Diseases / microbiology
        • Dog Diseases / microbiology
        • Dogs
        • Drug Resistance, Microbial
        • Feces / microbiology
        • Horse Diseases / microbiology
        • Horses
        • Microbial Sensitivity Tests
        • Salmonella / drug effects
        • Salmonella / isolation & purification
        • Salmonella Infections, Animal / microbiology

        References

        This article includes 6 references
        1. Neu HC, Cherubin CE, Longo ED, Flouton B, Winter J. Antimicrobial resistance and R-factor transfer among isolates of Salmonella in the northeastern United States: a comparison of human and animal isolates.. J Infect Dis 1975 Dec;132(6):617-22.
          pubmed: 1104721doi: 10.1093/infdis/132.6.617google scholar: lookup
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          pubmed: 323380doi: 10.1093/infdis/135.5.807google scholar: lookup
        3. Swanson EC, Collins MT. Use of the API 20E system to identify veterinary Enterobacteriaceae.. J Clin Microbiol 1980 Jul;12(1):10-4.
          pubmed: 6999012doi: 10.1128/jcm.12.1.10-14.1980google scholar: lookup
        4. Duck PD, Dillon JR, Lior H, Eidus L. Antibiotic resistance among predominant Salmonella serovars and phagovars in Canada.. Can J Microbiol 1978 Nov;24(11):1358-65.
          pubmed: 743644doi: 10.1139/m78-218google scholar: lookup
        5. Ling GV, Ruby AL. Gentamicin for treatment of resistant urinary tract infections in dogs.. J Am Vet Med Assoc 1979 Sep 1;175(5):480-1.
          pubmed: 387689
        6. Grant RB, Di Mambro L. Antimicrobial resistance and resistance plasmids in Salmonella from Ontario, Canada.. Can J Microbiol 1977 Sep;23(9):1266-73.
          pubmed: 332297doi: 10.1139/m77-190google scholar: lookup

        Citations

        This article has been cited 2 times.
        1. Mathewson JJ, Murray BE. Plasmid-mediated resistance to trimethoprim-sulfamethoxazole in Salmonella krefeld strains isolated in the United States. Antimicrob Agents Chemother 1983 Mar;23(3):495-6.
          doi: 10.1128/AAC.23.3.495pubmed: 6601930google scholar: lookup
        2. Tiemens KM, Shipley PL, Correia RA, Shields DS, Guerrant RL. Sulfamethoxazole-trimethoprim-resistant Shigella flexneri in northeastern Brazil. Antimicrob Agents Chemother 1984 May;25(5):653-4.
          doi: 10.1128/AAC.25.5.653pubmed: 6375563google scholar: lookup