Isolation of antibiotic-resistant Salmonella krefeld from clinical veterinary materials.
- Journal Article
Summary
The research is about isolating an antibiotic-resistant strain of Salmonella krefeld obtained from clinical veterinary samples.
Overview of the Research
In the process of investigating the occurrence and distribution of antibiotic resistance in Salmonella strains, the researchers isolated the bacteria Salmonella krefeld from different veterinary specimens. These bacterial isolates displayed a high level of resistance against multiple antibiotics commonly employed in the treatment of salmonellosis, an infection caused by Salmonella bacteria.
Isolation of Salmonella krefeld
The methodology of isolation was not detailed in the abstract, but it typically involves:
- Collection of samples from possibly infected animals or from their environment.
- Placing these samples into a selective growth media where the bacteria can proliferate.
- Isolating individual colonies of the bacterium for further analysis and identification.
Antibiotic Resistance of the Isolates
The Salmonella krefeld isolated in this study showed resistance to multiple antibiotics. Details about the specific antibiotics or the reasons for the resistance were not mentioned in the abstract. However, some common reasons for bacterial antibiotic resistance include:
- Mutations in the bacterial genome that result in resistance to the drug’s action.
- The ability of the bacterium to inactivate or eliminate the antibiotic before it can do any harm.
- The presence of plasmids, small circular DNA segments, that carry antibiotic resistance genes and can be transferred between bacteria.
Implications of the Findings
The implications of this study’s findings are significant:
- The presence of antibiotic-resistant strains of Salmonella in animals could pose severe health risks if they were to infect humans.
- Learning about antibiotic resistance in these strains helps in tailoring more effective treatment strategies in both veterinary and human medicine.
- The study emphasizes the necessity for continuous monitoring of antibiotic resistance in Salmonella strains in the veterinary setting to avoid potential future health crises.
Cite This Article
Publication
Researcher Affiliations
MeSH Terms
- Animals
- Anti-Bacterial Agents / pharmacology
- Cat Diseases / microbiology
- Cats
- Cattle
- Cattle Diseases / microbiology
- Dog Diseases / microbiology
- Dogs
- Drug Resistance, Microbial
- Feces / microbiology
- Horse Diseases / microbiology
- Horses
- Microbial Sensitivity Tests
- Salmonella / drug effects
- Salmonella / isolation & purification
- Salmonella Infections, Animal / microbiology
References
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Citations
This article has been cited 2 times.- Mathewson JJ, Murray BE. Plasmid-mediated resistance to trimethoprim-sulfamethoxazole in Salmonella krefeld strains isolated in the United States. Antimicrob Agents Chemother 1983 Mar;23(3):495-6.
- Tiemens KM, Shipley PL, Correia RA, Shields DS, Guerrant RL. Sulfamethoxazole-trimethoprim-resistant Shigella flexneri in northeastern Brazil. Antimicrob Agents Chemother 1984 May;25(5):653-4.