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Home / Equine Research Bank / Can Vet J / Jugular thrombophlebitis in horses: a review of fibrinolysis...
The Canadian veterinary journal = La revue veterinaire canadienne2013; 54(1); 65-71;

Jugular thrombophlebitis in horses: a review of fibrinolysis, thrombus formation, and clinical management.

Abstract: Thrombophlebitis of the jugular vein is commonly observed in horses, particularly during intensive care, and leads to local and systemic inflammatory responses as well as head and neck circulatory impairment. Thrombolytic therapy is widely used in human practice with the aim of thrombus dissolution and recanalization of the injured vessels. There are similarities between human and horse coagulation and fibrinolytic processes. This review examines the fibrinolytic system, thrombus formation, and the clinical management of jugular thrombophlebitis, including thrombolytic therapy. There is evidence that early regional thrombolytic therapy for jugular thrombophlebitis in horses may be effective to achieve sustained recanalization. La thrombophlébite de la veine jugulaire est communément observée chez les chevaux, particulièrement durant les soins intensifs, et cause des réactions inflammatoires locales et systémiques ainsi que des altérations de la circulation dans la tête et le cou. La thérapie thrombolytique est couramment utilisée en pratique humaine dans le but de dissoudre les thrombus et de recanaliser les vaisseaux blessés. Il y a similitudes entre les processus coagulant et fibrinolytique des humains et des chevaux. Cette revue examine le système fibrinolytique, la formation de thrombus et la gestion clinique de la thrombophlébite jugulaire, incluant la thérapie thrombolytique. Il y a des preuves que la thérapie thrombolytique régionale précoce pour la thrombophlébite jugulaire chez les chevaux peut être efficace pour la réalisation d’une recanalisation durable.(Traduit par Isabelle Vallières).
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Publication Date: 2013-07-03 PubMed ID: 23814304PubMed Central: PMC3524817
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article focuses on examining the process of fibrinolysis, thrombus formation and clinical management of jugular thrombophlebitis, a common condition in horses, particularly during intensive care, with significant implications on local and systemic inflammation and head and neck circulation.

Thrombophlebitis and Fibrinolytic Process

  • The research article discusses thrombophlebitis, which refers to the inflammation of a vein due to a blood clot, specifically in the jugular vein of horses. This condition is commonly seen in horses, particularly during intensive care.
  • A key part of the article revolves around the study of fibrinolysis, a process in the body that prevents blood clots from growing and becoming problematic by breaking down fibrin, a protein that when overproduced can lead to the formation of blood clots. The researchers indicate that this process has similarities in both horses and humans.

Thrombus Formation

  • The article examines the process of thrombus formation — the creation of a clot in the circulatory system. It points out how important understanding this process is in the management of thrombophlebitis given its implications on local and systemic inflammation and circulatory impairment in a horse’s head and neck.

Clinical Management

  • In terms of clinical management for jugular thrombophlebitis, the review talks about thrombolytic therapy as a common procedure for humans. In this therapy, medication is used to dissolve dangerous clots in blood vessels, improve blood flow, and prevent damage to tissues and organs.
  • The article demonstrates that there is evidence suggesting early regional thrombolytic therapy can be effective for horses suffering from jugular thrombophlebitis. This treatment aims to achieve sustained recanalization, which is the restoration of an opening in a blood vessel to enhance circulation throughout the body.

Overall, the research underlines the importance of further studies on fibrinolysis and thrombus formation as it can aid in optimizing clinical management strategies for jugular thrombophlebitis in horses, potentially through the early application of thrombolytic therapy.

Cite This Article

APA
Dias DP, de Lacerda Neto JC. (2013). Jugular thrombophlebitis in horses: a review of fibrinolysis, thrombus formation, and clinical management. Can Vet J, 54(1), 65-71.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 54
Issue: 1
Pages: 65-71

Researcher Affiliations

Dias, Deborah Penteado Martins
  • Departamento de Clínica e Cirurgia Veterinária, Faculdade de Ciências Agrárias e Veterinárias - FCAV/Unesp, Brazil. deborah_dias@hotmail.com
de Lacerda Neto, José Corrêa

    MeSH Terms

    • Animals
    • Blood Coagulation / physiology
    • Fibrinolysis / physiology
    • Fibrinolytic Agents / therapeutic use
    • Hemostasis
    • Horse Diseases / drug therapy
    • Horse Diseases / etiology
    • Horses
    • Jugular Veins
    • Risk Factors
    • Thrombolytic Therapy
    • Thrombophlebitis / drug therapy
    • Thrombophlebitis / etiology
    • Thrombophlebitis / veterinary
    • Thrombosis / drug therapy
    • Thrombosis / etiology
    • Thrombosis / veterinary

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