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Veterinary clinical pathology2018; 47(4); 654-659; doi: 10.1111/vcp.12660

Klossiella equi infection in a Cheval Canadien Mare.

Abstract: A 6-year-old Cheval Canadien mare was presented for clinical signs related to acute kidney injury after receiving a course of nonsteroidal anti-inflammatory therapy. Cytologic examination of concentrated urine revealed small protozoal organisms that were later identified as Klossiella equi. Both sporocysts and free-floating sporozoites were identified in the urine, which has not been previously documented. The mare responded well to intravenous fluid therapy, and as she regained tubular function, the presence of the protozoa in the urine also abated. The mare was discharged from the hospital after approximately 1 week of therapy. Repeat serum chemistries for up to 1 year following discharge demonstrated that all renal parameters had returned to normal, and the protozoa were not visualized on cytologic examination of the collected urine samples.
Publication Date: 2018-10-15 PubMed ID: 30321471DOI: 10.1111/vcp.12660Google Scholar: Lookup
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Summary

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A study presents the case of a 6-year-old horse that developed a kidney infection caused by Klossiella equi, a type of protozoa, following treatment with a nonsteroidal anti-inflammatory drug. The infection was successfully treated and the horse fully recovered.

Background

  • The subject of the study was a 6-year-old Cheval Canadien mare that had received a course of nonsteroidal anti-inflammatory therapy.
  • The horse showed clinical symptoms related to acute kidney injury. This was the first indication of a health issue.

Diagnosis

  • A cytologic examination of the horse’s concentrated urine revealed the presence of small protozoal organisms, later identified as Klossiella equi.
  • The presence of both sporocysts and free-floating sporozoites in the urine was noted. This had not previously been documented in cases involving Klossiella equi.

Treatment and Outcome

  • The mare was treated with intravenous fluid therapy and showed positive responses. As the function of the horse’s kidneys improved, the presence of the protozoa in its urine also decreased.
  • After about a week of treatment, the mare was discharged from the hospital.

Follow-up

  • Repeat serum chemistries were conducted for up to a year following the mare’s discharge. All the renal parameters had returned to normal within this period.
  • Additionally, the presence of the protozoa was not detected in the horse’s urine following its recovery.

Significance

  • The study presents an uncommon case where a horse developed a kidney infection caused by a protozoa called Klossiella equi following anti-inflammatory therapy.
  • The successful treatment of the infection and the full recovery of the horse provide important insights into the diagnosis, treatment and management of similar cases in the future.

Cite This Article

APA
Baker RE, Schlipf JW, Brady JV, Gorman ME. (2018). Klossiella equi infection in a Cheval Canadien Mare. Vet Clin Pathol, 47(4), 654-659. https://doi.org/10.1111/vcp.12660

Publication

ISSN: 1939-165X
NlmUniqueID: 9880575
Country: United States
Language: English
Volume: 47
Issue: 4
Pages: 654-659

Researcher Affiliations

Baker, Rose E
  • Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon.
Schlipf, John W
  • Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon.
Brady, Jacqueline V
  • Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon.
Gorman, M Elena
  • Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon.

MeSH Terms

  • Animals
  • Apicomplexa
  • Female
  • Horse Diseases / diagnosis
  • Horse Diseases / parasitology
  • Horses / parasitology
  • Protozoan Infections, Animal / diagnosis
  • Protozoan Infections, Animal / parasitology
  • Urine / parasitology

Citations

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