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The Canadian veterinary journal = La revue veterinaire canadienne2001; 42(6); 461-464;

Lack of antibodies to porcine circovirus type 2 virus in beef and dairy cattle and horses in western Canada.

Abstract: Porcine circovirus type 2 (PCV2) is a recently recognized agent that is consistently associated with postweaning multisystemic wasting disease in swine. There are conflicting data concerning the ability of this virus to infect and cause disease in other species. To determine if normal cattle, cattle affected with various illnesses, and normal horses in endemic areas of PCV2 infection in swine have had PCV2 infections, 100 randomly selected bovine sera, 100 equine sera, and 100 colostrum samples from clinically normal dairy cattle were examined for the presence of antibodies to porcine circoviruses by using ELISAs. All samples tested were negative for antibodies to porcine circoviruses. As well, a seronegative neonatal Holstein calf and 6 seronegative, 6-month-old beef calves that were experimentally infected with PCV2 failed to develop antibodies to the virus. These results suggest that natural infection of cattle and horses with PCV2 does not occur, or is a rare event, in western Canada.
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Publication Date: 2001-06-27 PubMed ID: 11424578PubMed Central: PMC1476552
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article investigates if Porcine circovirus type 2 (PCV2), a virus commonly associated with disease in swine, infects cattle and horses in western Canada. The study found no presence of PCV2 antibodies in the tested samples.

Objective

The objective of the research was to determine whether cattle (both normal and those affected with various illnesses) and horses in areas where PCV2 infection in pigs is commonly found have been infected by PCV2.

Methodology

  • The study examined a variety of samples to trace any sign of PCV2 infection:
  • A total of 100 bovine sera samples (randomly selected) were tested to see if they had contracted the virus.
  • Another 100 equine sera samples were also tested for the presence of PCV2.
  • Additionally, 100 colostrum (a type of milk produced by the mammary glands of mammals after giving birth) samples from clinically normal dairy cows were examined as well.
  • Experiments were performed involving a seronegative (one with no detectable antibodies) new born Holstein calf and six seronegative beef calves that were about 6 months old, who were infected with PCV2 to see if they developed antibodies to the virus.
  • All tests were performed using a type of test known as Enzyme-Linked Immunosorbent Assays (ELISAs), which identifies any antibodies that the body might have produced in response to the virus.

Results

  • None of the samples, including bovine sera, equine sera, and colostrum samples from dairy cows, had antibodies to porcine circoviruses, indicating a lack of PCV2 infection.
  • Similarly, the childless and beef calves that were experimentally infected with PCV2 also failed to generate antibodies against the virus.

Conclusion

The study concluded that natural infection by PCV2 in cattle and horses either does not occur or is a rare event in the region of western Canada. This provides valuable insight for the livestock industry and veterinary care providers in the region concerning the spread of PCV2.

Cite This Article

APA
Ellis JA, Konoby C, West KH, Allan GM, Krakowka S, McNeilly F, Meehan B, Walker I. (2001). Lack of antibodies to porcine circovirus type 2 virus in beef and dairy cattle and horses in western Canada. Can Vet J, 42(6), 461-464.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 42
Issue: 6
Pages: 461-464

Researcher Affiliations

Ellis, J A
  • Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Konoby, C
    West, K H
      Allan, G M
        Krakowka, S
          McNeilly, F
            Meehan, B
              Walker, I

                MeSH Terms

                • Animals
                • Antibodies, Viral / analysis
                • Cattle
                • Cattle Diseases / epidemiology
                • Cattle Diseases / immunology
                • Cattle Diseases / virology
                • Circoviridae Infections / epidemiology
                • Circoviridae Infections / immunology
                • Circoviridae Infections / veterinary
                • Circovirus / immunology
                • Circovirus / pathogenicity
                • Colostrum / immunology
                • Enzyme-Linked Immunosorbent Assay / methods
                • Enzyme-Linked Immunosorbent Assay / veterinary
                • Horse Diseases / epidemiology
                • Horse Diseases / immunology
                • Horse Diseases / virology
                • Horses

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                Citations

                This article has been cited 8 times.
                1. Hui A, Altan E, Slovis N, Fletcher C, Deng X, Delwart E. Circovirus in Blood of a Febrile Horse with Hepatitis. Viruses 2021 May 20;13(5).
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                3. Zhai SL, Chen RA, Chen SN, Wen XH, Lv DH, Wu DC, Yuan J, Huang Z, Zhou XR, Luo ML, He DS, Wei WK. First molecular detection of porcine circovirus type 2 in bovids in China. Virus Genes 2014 Dec;49(3):507-11.
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