Laminitis as a systemic disease.
- Journal Article
- Review
Summary
This research article focuses on laminitis as a systemic disease, examining its impact on various body systems in horses and the role of nutritional and metabolic changes in chronic cases.
Understanding Laminitis as a Systemic Disease
Laminitis is a condition primarily associated with horses. The study examines this disease from a wider perspective, viewing it as a systemic disease that impacts various systems within the body such as the cardiovascular, renal, endocrine, and immunologic systems. This view proposes a more comprehensive understanding of the disease and its potential impacts beyond the often singular focus on the horse’s feet.
- Cardiovascular system: The researchers look into how laminitis might affect heart and blood vessels. This could include changes in heart rate, blood pressure, or circulatory function.
- Renal system: Laminitis’ impacts on a horse’s kidneys and urinary function are also discussed, which might explain potential changes in urine production and composition.
- Endocrine system: The influence of laminitis on the body’s hormones and overall metabolic regulation is investigated. Hormonal imbalances can lead to a range of health issues in horses, including changes in behaviour, weight, and coat condition.
- Immunologic system: The interaction between laminitis and the horse’s immune response is another focus of this study. An understanding of this relationship would shed light on how the disease might make horses more susceptible to other infections or conditions and impact their overall health.
Nutritional and Metabolic Alterations in Chronic Laminitis
The study further delves into the nutritional and metabolic changes that occur in horses suffering from chronic laminitis. It presents a compelling exploration of how the disease might lead to alterations in the horse’s nutrient intake, metabolism, and overall health over an extended period.
- Nutritional changes: The researchers examine the possibility of changes in a horse’s diet or nutrition due to laminitis, potentially due to changes in appetite, digestion, or dietary requirements.
- Metabolic alterations: The changes in metabolism due to chronic laminitis are also investigated, which may explain possible weight changes, lethargy, or other health impacts in a horse suffering from the disease over a long term.
Implications of Systemic Findings
By recognizing and exploring laminitis as a systemic disease, the study aims to provide a more well-rounded understanding of its effects on a horse’s whole-body health. The clinical implications of these systemic findings are discussed, aiming to guide better diagnosis, treatment, and management strategies for horses affected by laminitis.
- Better diagnosis: If recognized as a systemic disease, veterinarians might consider laminitis in assessing seemingly unrelated health issues in horses, potentially leading to earlier detection of the disease.
- Improved treatment: Understanding the potential wide-ranging effects of laminitis could permit more effective treatment approaches, addressing not only the immediate symptoms but also the underlying systemic impacts.
- More effective management strategies: This systemic perspective might inform enhanced management strategies for laminitis, considering the horse’s overall health, diet, and lifestyle factors.
Cite This Article
Publication
Researcher Affiliations
- Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine, Texas A&M University, College Station, USA.
MeSH Terms
- Animal Nutritional Physiological Phenomena
- Animals
- Cardiovascular Diseases / complications
- Cardiovascular Diseases / veterinary
- Chronic Disease
- Endocrine System Diseases / complications
- Endocrine System Diseases / veterinary
- Foot Diseases / complications
- Foot Diseases / veterinary
- Hoof and Claw
- Horse Diseases
- Horses
- Immune System / physiopathology
- Inflammation / complications
- Inflammation / veterinary
- Kidney Diseases / complications
- Kidney Diseases / veterinary
Citations
This article has been cited 3 times.- Gehlen H, Jaburg N, Merle R, Winter J. Can Endocrine Dysfunction Be Reliably Tested in Aged Horses That Are Experiencing Pain?. Animals (Basel) 2020 Aug 14;10(8).
- Steelman SM, Chowdhary BP. Plasma proteomics shows an elevation of the anti-inflammatory protein APOA-IV in chronic equine laminitis. BMC Vet Res 2012 Sep 27;8:179.
- Haritou SJ, Zylstra R, Ralli C, Turner S, Tortonese DJ. Seasonal changes in circadian peripheral plasma concentrations of melatonin, serotonin, dopamine and cortisol in aged horses with Cushing's disease under natural photoperiod. J Neuroendocrinol 2008 Aug;20(8):988-96.