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Clinical oral implants research2021; 33(2); 142-149; doi: 10.1111/clr.13873

Lateral alveolar ridge augmentation using an equine-derived collagen-containing bone block: A prospective case series.

Abstract: To assess the clinical performance of an equine-derived collagen-containing bone block (CXBB) for lateral alveolar ridge augmentation and staged implant placement. Methods: A total of n = 16 patients (16 implants) had received a modified surgical protocol for lateral ridge augmentation using a size-adapted rigidly fixed CXBB and contour augmentation. After 26 weeks of submerged healing, the primary endpoint was defined as the final ridge width (RW26) sufficient to place an adequately dimensioned titanium implant at the respective sites. Secondary outcomes included the gain in ridge width (RWg) and the need for secondary grafting. Clinical outcomes (bleeding on probing-BOP, probing depth-PD, and mucosal recession-MR) were assessed at implant loading and after a median observation period of 12.3 months. Results: In all patients (n = 16) investigated, RW26 allowed for a successful placement of an adequately dimensioned titanium implant at respective sites exhibiting mean RWg values of 5.09 ± 1.07 mm. A soft tissue dehiscence was noted in one patient (6.3%), and a secondary grafting was needed in two patients (12.5%) The changes in mean BOP, PD, and MR values at V9 amounted to 10.23 ± 30.11%, 0.14 ± 0.80 mm, and -0.01 ± 0.04 mm, respectively. Conclusions: CXBB may represent a feasible approach for lateral alveolar ridge augmentation and two-stage implant placement.
© 2021 The Authors. Clinical Oral Implants Research published by John Wiley & Sons Ltd.
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Publication Date: 2021-10-30 PubMed ID: 34679206DOI: 10.1111/clr.13873Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article investigates the effectiveness of using a bone block containing collagen from horses, referred to as CXBB, to increase the width of the alveolar ridge (a part of the upper or lower jawbones that houses the sockets of the teeth) before a dental implant is inserted. CXBB was found to successfully allow for the placement of adequately sized titanium implants in all studied patients, making it a promising method for alveolar ridge augmentation and two-stage implant placement.

Methods

  • The study consisted of 16 patients who received a modified surgical protocol for lateral ridge augmentation using a CXBB. The dimensions of the bone block were tailored for each patient and rigidly fixed in place. In addition, a contour augmentation procedure was performed.
  • The patients were observed during a submerged healing period of 26 weeks, after which the primary endpoint of success was established as the ability to implant a correctly sized titanium implant at the surgical site.
  • Secondary outcomes evaluated during the study included the increase in ridge width (RWg) and the necessity for secondary grafting.
  • Various clinical parameters including bleeding upon probing (BOP), probing depth (PD), and mucosal recession (MR) were assessed at the time of implant placement, and after an average observation period of 12.3 months.

Results

  • The study concluded that in all patients, sufficient ridge width (RW26) was achieved to place properly sized titanium implants. The average increase in ridge width was 5.09 mm with a standard deviation of 1.07 mm.
  • Instances of complications were low. Soft tissue dehiscence (separation or rupture) was noted in 1 patient (representing 6.3% of the sample), and secondary grafting was necessary in 2 patients (or 12.5% of the sample).
  • The mean changes in probing depth, bleeding upon probing, and mucosal recession were small. Thus, the surgical sites were generally healthy and appropriate for the placement of an implant.

Conclusion

  • Based on the results, the researchers suggest that using an equine-derived collagen-containing bone block (CXBB) may be an effective solution for lateral alveolar ridge augmentation prior to the two-stage placement of a titanium implant.

Cite This Article

APA
Parvini P, Mihatovic I, Sahin D, Becker J, Schwarz F. (2021). Lateral alveolar ridge augmentation using an equine-derived collagen-containing bone block: A prospective case series. Clin Oral Implants Res, 33(2), 142-149. https://doi.org/10.1111/clr.13873

Publication

Clinical oral implants research
ISSN: 1600-0501
NlmUniqueID: 9105713
Country: Denmark
Language: English
Volume: 33
Issue: 2
Pages: 142-149

Researcher Affiliations

Parvini, Puria
  • Department of Oral Surgery and Implantology, Goethe University, Frankfurt, Germany.
Mihatovic, Ilja
  • Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
Sahin, Didem
  • Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
Becker, Jürgen
  • Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
Schwarz, Frank
  • Department of Oral Surgery and Implantology, Goethe University, Frankfurt, Germany.
  • Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.

MeSH Terms

  • Adaptation, Physiological
  • Alveolar Ridge Augmentation
  • Animals
  • Bone Transplantation
  • Collagen
  • Dental Implantation, Endosseous
  • Horses
  • Humans
  • Prospective Studies

Grant Funding

  • Geistlich Pharma AG, Switzerland

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This article includes 20 references
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Citations

This article has been cited 2 times.
  1. Christensen JG, Grønlund GP, Georgi SR, Starch-Jensen T, Bruun NH, Jensen SS. Horizontal Alveolar Ridge Augmentation with Xenogenic Block Grafts Compared with Autogenous Bone Block Grafts for Implant-retained Rehabilitation: a Systematic Review and Meta-Analysis. J Oral Maxillofac Res 2023 Apr-Jun;14(2):e1.
    doi: 10.5037/jomr.2023.14201pubmed: 37521322google scholar: lookup
  2. Lim HC, Paeng KW, Jung UW, Benic GI. Vertical bone augmentation using collagenated or non-collagenated bone substitute materials with or without recombinant human bone morphogenetic protein-2 in a rabbit calvarial model. J Periodontal Implant Sci 2023 Dec;53(6):429-443.
    doi: 10.5051/jpis.2204240212pubmed: 37038830google scholar: lookup
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