Longitudinal study of Australian stringhalt cases in France.

The research article studies 70 horses in France affected by Australian stringhalt – a neuromuscular disorder – from 2003 to 2008, examining their symptoms, recovery rates, and effective treatments.

Study Overview

• The researchers conducted a longitudinal study of 70 horses experiencing clinical evidence of Australian stringhalt in France over a period of five years (2003 to 2008).
• With the exception of one horse, all had a history of bilateral stringhalt and had grazed pastures containing Hypochoeris radicata (L.), a type of flowering plant.

Symptoms and Effects on the Horses

• The horses showcased symptoms like hind legs hyper-flexibility and unusual gait due to a distal axonopathy, a disorder that results in muscle denervation and atrophy.
• About 50% of the horses recovered naturally in 8 months, while especially affected horses failed to recover, however they appeared healthy on dry, warm days.
• These horses also showed signs of depression or aggressive behavior, implying an impact on the central nervous system.

Treatment

• The use of phenytoin, a medication for seizures, led to a quick, distinct improvement of stringhalt in some horses.
• The administration of taurine, an amino acid, seemed to improve behavior disorders.
• Horses deeply affected by stringhalt (grade III and beyond according to Huntington’s classification) needed to be treated with phenytoin, particularly during damp, muddy weather. Despite this treatment, these horses still displayed signs of stringhalt when scared or initially set to work.

This research offers vital insights into Australian stringhalt, its effects on horses, and potential treatments, providing a scientific basis for improving the quality of life of horses affected by this neuromuscular disorder.