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Animal reproduction science2006; 99(1-2); 213-220; doi: 10.1016/j.anireprosci.2006.05.018

Luteal blood flow and progesterone production in mares.

Abstract: The temporal relationships between blood flow in the corpus luteum (CL) and circulating progesterone concentrations were studied in 20 mares. Retrospective inspection of plasma progesterone concentrations indicated that a precipitous decrease occurred during Days 15-17 (Day 0 = ovulation) and was defined as the luteolytic period. Mean percentage of CL with color-Doppler signals for blood flow was maximum on Day 10 (77.3%), and Days 10-14 (49.8%) were defined as the preluteolytic period. The cross-sectional area of the CL decreased progressively from Day 4 (9.0 cm2) to Day 19 (1.5 cm2). Progesterone reached maximum concentration on Day 8 (12.8 ng/ml) and thereafter CL area and plasma progesterone decreased in parallel until the onset of luteolysis. During the luteolytic period, the decrease in plasma progesterone was about sixfold greater than during the preluteolytic period, whereas the decrease in CL area and in percentage of CL with blood-flow area were about twofold greater. There was no indication that an acute increase or decrease in luteal blood flow occurred prior to the precipitous decrease in plasma progesterone.
(c)2006 Elsevier B.V. All rights reserved.
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Publication Date: 2006-05-22 PubMed ID: 16815650DOI: 10.1016/j.anireprosci.2006.05.018Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article investigates the relationship between blood flow in the corpus luteum (CL) and circulating progesterone levels in mares. It reveals that a significant decrease in progesterone and blood flow to the CL transpires around days 15-17 (taking ovulation as day 0) and decreases further towards days 19, hinting this might be tied to the reproductive cycle in mares.

Study Overview

  • The researchers studied the temporal relationships between the corpus luteum (CL) blood flow and circulating concentrations of progesterone in 20 mares.
  • This study aimed to determine the correlation between progesterone levels and CL blood flow, and how these are connected to the reproductive cycle of mares.

Key Findings

  • The researchers found a significant decrease in plasma progesterone concentrations on Days 15-17, a period referred to as the luteolytic period.
  • There was an observable maximum mean percentage of CL with color-Doppler signals showing blood flow on Day 10, and the period from Days 10-14 was defined as the preluteolytic period.
  • The cross-sectional area of the CL diminished gradually from Day 4 to Day 19.
  • It was noted that progesterone reached maximum concentration on Day 8, thereafter, the CL area and plasma progesterone dropped in parallel until the beginning of luteolysis.
  • The decrease in plasma progesterone during the luteolytic period was approximately six times greater than during the preluteolytic period. Meanwhile, the decrease in CL area and blood-flow area within the CL were about twofold greater.
  • There was no evidence suggesting an abrupt increase or decrease in luteal blood flow prior to the significant decrease in plasma progesterone.

Significance

  • Understanding the relationship between luteal blood flow and progesterone production in mares provides valuable insights into the physiological and hormonal changes during their reproductive cycle.
  • The findings could contribute to the improved reproductive management of mares and other equine animals.

Cite This Article

APA
Ginther OJ, Gastal EL, Gastal MO, Utt MD, Beg MA. (2006). Luteal blood flow and progesterone production in mares. Anim Reprod Sci, 99(1-2), 213-220. https://doi.org/10.1016/j.anireprosci.2006.05.018

Publication

Animal reproduction science
ISSN: 0378-4320
NlmUniqueID: 7807205
Country: Netherlands
Language: English
Volume: 99
Issue: 1-2
Pages: 213-220

Researcher Affiliations

Ginther, O J
  • Eutheria Foundation, Cross Plains, WI 53528, USA. ginther@svm.vetmed.wisc.edu
Gastal, E L
    Gastal, M O
      Utt, M D
        Beg, M A

          MeSH Terms

          • Animals
          • Blood Flow Velocity / physiology
          • Blood Vessels / diagnostic imaging
          • Corpus Luteum / blood supply
          • Corpus Luteum / diagnostic imaging
          • Estrous Cycle / physiology
          • Female
          • Horses / physiology
          • Linear Models
          • Progesterone / blood
          • Progesterone / metabolism
          • Retrospective Studies
          • Time Factors
          • Ultrasonography, Doppler / veterinary

          Citations

          This article has been cited 17 times.
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