Magnetic Resonance Imaging-Guided Treatment of Equine Distal Interphalangeal Joint Collateral Ligaments: 2009-2014.
Abstract: To determine the outcome of treating distal interphalangeal joint collateral ligament (DIJCL) desmopathy using magnetic resonance imaging (MRI)-guided ligament injection. Methods: Medical records of 13 adult horses diagnosed with DIJCL desmopathy using low-field MRI and treated by MRI-guided ligament injection of mesenchymal stem cells and/or platelet-rich plasma (PRP) were reviewed. Information collected included signalment, MRI diagnosis, treatment type, time to resolution of lameness, and level of exercise after treatment. Results: Collateral ligament inflammation was diagnosed as a cause of lameness in 13 horses. MRI was used to guide the injection of the injured DIJCL. All lameness attributed to DIJCL desmopathy resolved with the resulting level of performance at expected (10) or less than expected (3). Conclusions: Injection of the DIJCL can be safely completed in horses standing in a low-field magnet guided by MRI as previously demonstrated in cadaver specimens. The positive response in all horses suggests that administration of stem cells or PRP along with rest and appropriate shoeing may be a safe and useful treatment for DIJCL desmopathy.
Publication Date: 2016-09-05 PubMed ID: 27656645PubMed Central: PMC5011138DOI: 10.3389/fvets.2016.00073Google Scholar: Lookup
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Summary
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The research focuses on the usage of magnetic resonance imaging (MRI)-guided treatment for lameness in horses, specifically resulting from inflammation of the distal interphalangeal joint collateral ligament (DIJCL). Using a combination of mesenchymal stem cells and/or platelet-rich plasma (PRP), the study posits that the treatment can safely and effectively mitigate the issue.
Research Methodology
- The study involved the scrutiny of medical records of 13 adult horses diagnosed with DIJCL desmopathy via low-field MRI.
- The horses were treated via MRI-guided ligament injection of mesenchymal stem cells and/or platelet-rich plasma (PRP).
- The details collected from the records covered aspects like the identification of the horses, the diagnosis through MRI, the type of treatment administered, the duration taken for lameness to go away, and the degree of activity post-treatment.
Key Findings
- It was confirmed that inflammation of the DIJCL was indeed causing lameness in all 13 horses.
- MRI was utilized to guide the injection into the affected DIJCL.
- All indicators of lameness that could be attributed to DIJCL inflammation were found to have resolved post-treatment.
- The level of performance post-treatment was either as expected in 10 cases or slightly lower than expected in 3 cases.
Conclusions from the Study
- The study confirmed that injecting the DIJCL can be safely carried out on horses in a non-operational state in a low-field magnetic environment with the guidance of an MRI.
- The response gathered from all the horses positively implies that the use of stem cells or PRP combined with rest and appropriate shoeing can be a safe and potentially effective treatment approach for DIJCL desmopathy.
Cite This Article
APA
White NA, Barrett JG.
(2016).
Magnetic Resonance Imaging-Guided Treatment of Equine Distal Interphalangeal Joint Collateral Ligaments: 2009-2014.
Front Vet Sci, 3, 73.
https://doi.org/10.3389/fvets.2016.00073 Publication
Researcher Affiliations
- Marion duPont Scott Equine Medical Center, Virginia-Maryland College of Veterinary Medicine, Virginia Tech , Leesburg, VA , USA.
- Marion duPont Scott Equine Medical Center, Virginia-Maryland College of Veterinary Medicine, Virginia Tech , Leesburg, VA , USA.
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