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Veterinary research communications1993; 17(6); 449-457; doi: 10.1007/BF01839212

Mal seco, a grass sickness-like syndrome of horses in Argentina.

Abstract: Mal seco is a grass sickness-like syndrome of horses which has mainly been observed in Patagonia, Argentina, although some reports indicate that the disease may exist in other Argentinian provinces and in the south of Chile. The aetiology of mal seco remains unknown but the disease seems to be restricted to animals grazing on natural pastures and not receiving supplementary feeding. Mal seco is clinically characterized by total or partial bowel stasis and the main findings at post-mortem examination are almost exclusively restricted to the bowel. The most striking histopathological changes found consisted of degenerative changes in the coeliaco-mesenteric ganglia and also in other central and peripheral structures of the nervous system.
Publication Date: 1993-01-01 PubMed ID: 8030198DOI: 10.1007/BF01839212Google Scholar: Lookup
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Summary

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This research article discusses Mal seco, a syndrome similar to grass sickness observed in horses located mostly in Patagonia, Argentina. The cause of Mal seco is unknown, but appears to affect horses grazing on natural pastures without any supplementary feeding. The condition is clinically characterized by total or partial bowel stasis and affects the nervous system.

Clinical Features of Mal seco

  • Mal seco is a syndrome observed in horses in Argentina, similar to the grass sickness disease.
  • Most cases are reported in Patagonia, Argentina, with some cases also reported in other provinces and in southern Chile.
  • The condition is typically observed in horses that graze on natural pastures without receiving any supplementary feeding, suggesting a potential link between the disease and the animal’s diet.
  • Clinical symptoms are characterized by total or partial bowel stasis, indicating a major effect on the digestive system of the affected horses.

Aetiology and Pathology of Mal seco

  • The exact cause or aetiology of mal seco remains undiscovered. Studies show that it might be linked to grazing habits and diet, but no concrete evidence has been found.
  • Post-mortem examinations have provided further insight into the effects of the disease on the horse’s body.
  • The most evident changes due to mal seco are found in the bowel, which align with the clinical symptoms of bowel stasis.
  • The condition also causes degenerative changes in the nervous system, specifically in the coeliaco-mesenteric ganglia and other central and peripheral structures. This aspect of the disease indicates an extensive impact beyond the digestive system, affecting the overall neurological health of the horse.

Implications and Future Research

  • Given its potential to affect horses’ health severely, understanding the cause and treatment of mal seco is important for managing equine health, particularly in regions where the disease is prevalent.
  • Future research should focus on identifying the aetiology of the disease, understanding its effect on the nervous system, and developing effective treatments or preventative measures.

Cite This Article

APA
Uzal FA, Robles CA. (1993). Mal seco, a grass sickness-like syndrome of horses in Argentina. Vet Res Commun, 17(6), 449-457. https://doi.org/10.1007/BF01839212

Publication

ISSN: 0165-7380
NlmUniqueID: 8100520
Country: Switzerland
Language: English
Volume: 17
Issue: 6
Pages: 449-457

Researcher Affiliations

Uzal, F A
  • Animal Health Unit, National Institute of Agricultural Technology (INTA), Bariloche, Argentina.
Robles, C A

    MeSH Terms

    • Acute Disease
    • Animals
    • Argentina / epidemiology
    • Chronic Disease
    • Digestive System / pathology
    • Ganglia, Sympathetic / pathology
    • Horse Diseases / epidemiology
    • Horse Diseases / etiology
    • Horse Diseases / pathology
    • Horses
    • Poaceae
    • Syndrome

    References

    This article includes 7 references
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      pubmed: 13263453
    6. Uzal FA, Robles CA, Olaechea FV. Histopathological changes in the coeliaco-mesenteric ganglia of horses with 'mal seco', a grass sickness-like syndrome, in Argentina.. Vet Rec 1992 Mar 21;130(12):244-6.
      pubmed: 1285752doi: 10.1136/vr.130.12.244google scholar: lookup
    7. Gilmour JS, Brown R, Johnson P. A negative serological relationship between cases of grass sickness in Scotland and Clostridium perfringens type A enterotoxin.. Equine Vet J 1981 Jan;13(1):56-8.

    Citations

    This article has been cited 1 times.
    1. Laus F, Corsalini J, Mandara MT, Bazzano M, Bertoletti A, Gialletti R. Equine grass sickness in italy: a case series study.. BMC Vet Res 2021 Aug 6;17(1):264.
      doi: 10.1186/s12917-021-02966-ypubmed: 34362361google scholar: lookup