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Veterinary sciences2021; 8(10); 202; doi: 10.3390/vetsci8100202

Measurement of Tissue Oximetry in Standing Unsedated and Sedated Horses.

Abstract: Near infrared spectroscopy (NIRS) noninvasively measures peripheral tissue oxygen saturation (StO) and may be useful to detect early changes in StO in anaesthetized and critically ill horses. This study aimed to identify the muscle belly that provided the highest percentage of successful StO readings and the highest mean StO value. Fifty adult horses were enrolled in a prospective controlled study. StO was measured at six different muscles in each horse, for each intervention: hair overlying the muscle was clipped (post clipping: PC), clipped skin was cleaned with chlorhexidine (post-surgical prepping: PP) and medetomidine was administered intravenously (post medetomidine: PM). Mean StO values were calculated for each muscle, and a linear effects model was used to assess the effect of muscle group and intervention on StO. The sartorius muscle gave the highest percentage of successful StO values ( < 0.001) and the highest mean (90% CI) StO values for the PC, PP and PM interventions. Surgical prepping of the skin increased the success for measurement of StO values. For all muscles, administration of medetomidine was associated with lower StO values ( < 0.001). In conclusion, of the muscles examined, the sartorius muscle may be the preferred muscle to measure StO in horses, and clipping and cleaning of the probe placement site is recommended.
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Publication Date: 2021-09-22 PubMed ID: 34679032PubMed Central: PMC8537620DOI: 10.3390/vetsci8100202Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research study used Near Infrared Spectroscopy (NIRS) technology to measure the oxygen levels in the muscles of horses with the aim of identifying which muscle provided the most accurate readings and how specific interventions influenced the readings, particularly in anaesthetized and critically ill horses.

Methodology

  • The study was conducted on fifty adult horses. It was a prospective controlled study, meaning the researchers were looking forward, observing the effects and outcomes of their interventions, and the conditions were controlled or manipulated by the researchers for the study.
  • Six different muscles from each horse were examined, as different muscles might return different readings of tissue oxygen saturation (StO).
  • Readings were taken at three stages: after the hair over the muscle was clipped (PC), after the clipped skin was cleaned with an antiseptic agent called chlorhexidine (PP), and after the horse had been administered an injection of medetomidine, a sedative (PM). These interventions were designed to assess how preparation of the test area and sedation might impact oxygen saturation readings.

Findings

  • The sartorius muscle consistently gave the highest percentage of successful measurements and the highest mean StO values under all three interventions. This suggests that this muscle may be the most reliable for taking StO measurements in horses.
  • Prepping the skin surgically by clipping hair and cleaning the site increased the success rate for recording StO values. This implies that good preparation of the test site improves the accuracy of the readings.
  • Administration of medetomidine resulted in lower StO values across all muscles. This indicates that the sedative impacts tissue oxygen levels and that its use could possibly skew the results of such measurements.

Conclusion

  • As a result of their findings, the researchers recommend the sartorius muscle as the preferred site for measuring StO in horses.
  • Proper preparation of the site by clipping hair and cleaning with an antiseptic is advised for accurate readings.
  • The impact of medetomidine on StO readings needs to be taken into account when assessing the oxygen levels in sedated horses.

Cite This Article

APA
Cowling N, Woldeyohannes S, Sole Guitart A, Goodwin W. (2021). Measurement of Tissue Oximetry in Standing Unsedated and Sedated Horses. Vet Sci, 8(10), 202. https://doi.org/10.3390/vetsci8100202

Publication

Veterinary sciences
ISSN: 2306-7381
NlmUniqueID: 101680127
Country: Switzerland
Language: English
Volume: 8
Issue: 10
PII: 202

Researcher Affiliations

Cowling, Nicholas
  • Gatton Campus, School of Veterinary Science, The University of Queensland, Gatton 4343, Australia.
Woldeyohannes, Solomon
  • Gatton Campus, School of Veterinary Science, The University of Queensland, Gatton 4343, Australia.
Sole Guitart, Albert
  • Gatton Campus, School of Veterinary Science, The University of Queensland, Gatton 4343, Australia.
Goodwin, Wendy
  • Gatton Campus, School of Veterinary Science, The University of Queensland, Gatton 4343, Australia.

Grant Funding

  • 458 / John and Mary Kibble Trust

Conflict of Interest Statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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Citations

This article has been cited 1 times.
  1. Frabasile L, Amendola C, Buttafava M, Chincarini M, Contini D, Cozzi B, De Zani D, Guerri G, Lacerenza M, Minero M, Petrizzi L, Qiu L, Rabbogliatti V, Rossi E, Spinelli L, Straticò P, Vignola G, Zani DD, Dalla Costa E, Torricelli A. Non-invasive estimation of in vivo optical properties and hemodynamic parameters of domestic animals: a preliminary study on horses, dogs, and sheep. Front Vet Sci 2023;10:1243325.
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