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Measurement of tracheal mucous transport rate in the horse.

Abstract: Tracheal mucous transport rates were measured in 12 nonanesthetized horses after an intratracheal injection of 99mtechnetium-sulfur colloid. The transport rate of the subsequent bolus of radioactivity was determined, using a portable scaler rate meter fitted with a high-energy gamma-scintillation probe. A gamma-scintillation camera was used to verify bolus form and movement in 1 horse. The mean tracheal mucous transport rate was 1.66 +/- 0.24 cm/min.
Publication Date: 1983-06-01 PubMed ID: 6870026
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The study focuses on measuring the rate of tracheal mucus transportation in 12 non-anesthetized horses using a radioactive tracer and advanced monitoring equipment.

Objective and Methodology:

  • The research sought to measure the rate at which mucus is transported in a horse’s trachea. This was part of an effort to understand better the horse’s respiratory system and potentially diagnose or even treat related ailments. The rate of movement of a particular substance can often provide insight into the state or health of the system it is moving within.
  • To do this, the researchers injected a radioactive substance known as 99mtechnetium-sulfur colloid into the trachea of 12 horses that were not under anesthesia. The radioactive substance was used because its progress could be tracked with certain equipment and would show up more clearly on imaging compared to a non-radioactive substance.
  • The researchers then tracked the movement of the radioactive substance through the horses’ trachea using a portable scaler rate meter that was equipped with a gamma-scintillation probe. This instrument is capable of detecting the gamma radiation emitted by the radioactive substance and can therefore track its movement over time.
  • In addition, the research team used a gamma-scintillation camera to verify the shape and movement of the radioactive substance within one of the horses. This was likely done to correct for uncertainties and provide a real-time visual reference during the experiment.

Results:

  • The results indicated that the average rate of mucus transportation in the horse’s trachea was around 1.66 cm/min with a standard deviation of 0.24. This essentially means that mucus in a horse’s trachea moves at this average speed, though there is some variation between individual horses.
  • This baseline rate of tracheal mucus transportation could be used in future research and comparisons. For instance, if a horse were observed to have a significantly different rate of mucus transport, this might indicate a potential health issue related to its respiratory system.

Cite This Article

APA
Nelson R, Hampe DW. (1983). Measurement of tracheal mucous transport rate in the horse. Am J Vet Res, 44(6), 1165-1166.

Publication

ISSN: 0002-9645
NlmUniqueID: 0375011
Country: United States
Language: English
Volume: 44
Issue: 6
Pages: 1165-1166

Researcher Affiliations

Nelson, R
    Hampe, D W

      MeSH Terms

      • Animals
      • Female
      • Horses / physiology
      • Male
      • Mucous Membrane / metabolism
      • Technetium
      • Trachea / metabolism

      Citations

      This article has been cited 1 times.
      1. Willoughby RA, Ecker GL, McKee SL, Riddolls LJ. Use of scintigraphy for the determination of mucociliary clearance rates in normal, sedated, diseased and exercised horses. Can J Vet Res 1991 Oct;55(4):315-20.
        pubmed: 1790485