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Home / Equine Research Bank / PeerJ / Mechanical nociceptive assessment of the equine hoof followi...
PeerJ2020; 8; e9469; doi: 10.7717/peerj.9469

Mechanical nociceptive assessment of the equine hoof following distal interphalangeal joint intra-articular anesthesia.

Abstract: With the hypothesis that equine dorsal lamellar tissue can be desensitized by anesthesia injection into distal interphalangeal joint (DIPJ), the objective was to assess the mechanical nociceptive threshold of hoof dorsal lamellae following intra-articular (IA) administration of lidocaine into this joint. Methods: The DIPJ of the forelimbs of six adult healthy horses were injected with either 5 mL of lidocaine, or 5 mL of lactated Ringer's solution. Treatments were randomly distributed, with each forelimb undergoing a single treatment. The hooves were evaluated pre- and post-injection at pre-selected times over 4 h, using a pressure algometry model. Mechanical nociceptive thresholds (MNTs) were recorded for the sole (dorsal, palmarolateral, and palmaromedial regions), coronary band (medial, lateral, and dorsal regions), heel bulbs (medial and lateral), and dorsal lamellar region (2 cm and 4 cm distal to the coronary band). The MNT means were compared over time using the Friedman test and between treatments using the Wilcoxon signed-rank test, with values of  < 0.05 considered statistically significant. Results: There were no differences between treatments for any region of the hoof during the evaluation period. However, MNT values indicating analgesia were recorded in the dorsal lamellar region in 50% of hooves following adminstration of lidocaine into the DIPJ. Conclusions: The administration of 5 mL of lidocaine into the DIPJ does not significantly increase the mechanical nociceptive threshold of the equine hoof.
©2020 Malacarne et al.
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Publication Date: 2020-08-11 PubMed ID: 32864201PubMed Central: PMC7427544DOI: 10.7717/peerj.9469Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research examines whether an anesthesia injection into a specific horse joint, the distal interphalangeal joint, can numb the dorsal lamellar tissue in the hoof. Through a series of tests, it becomes clear that lidocaine injection does not significantly increase the hoof’s resistance to mechanical pain.

Objective and Hypothesis

  • The overall aim of this research is to determine whether injecting anesthetic into the distal interphalangeal joint (DIPJ) of a horse can numb the dorsal lamellar tissue within the hoof.
  • The hypothesis was that injecting anesthesia into the DIPJ could desensitize the dorsal lamellar tissue.

Methodology

  • The study involved the DIPJ of the forelimbs of six adult horses.
  • Each forelimb was given a single treatment, which involved injecting either 5 mL of lidocaine, an anesthetic solution, or 5 mL of lactated Ringer’s solution, a non-anesthetic solution. The allocation of treatments was random.
  • Pre- and post-injection evaluations of the hooves were conducted over a four-hour period using a pressure measurement model.
  • Mechanical nociceptive thresholds (MNTs), indicators of the hoof’s sensitivity to pain, were measured across different regions of the hoof.

Statistical Analysis

  • MNT means were analyzed over time with the Friedman test to see if there were any significant changes post-injection.
  • The Wilcoxon signed-rank test was used to compare treatments and see if lidocaine increased the hoof’s resistance to mechanical pain.
  • Statistical significance was determined by values less than 0.05.

Results

  • The study found no significant differences between treatments for any region of the hoof during the evaluation period.
  • However, numbness indicated by MNT values was recorded in the dorsal lamellar region in half of the hooves following the administration of lidocaine into the DIPJ.

Conclusion

  • Despite some instances of numbness in the dorsal lamellar region, the overall conclusion of the study is that injecting 5 mL of lidocaine into the DIPJ does not significantly increase the mechanical nociceptive threshold of the equine hoof.

Cite This Article

APA
Malacarne BD, Cota LO, Neto ACP, Paz CFR, Dias LA, Corrêa MG, Carvalho AM, Faleiros RR, Xavier ABS. (2020). Mechanical nociceptive assessment of the equine hoof following distal interphalangeal joint intra-articular anesthesia. PeerJ, 8, e9469. https://doi.org/10.7717/peerj.9469

Publication

PeerJ
ISSN: 2167-8359
NlmUniqueID: 101603425
Country: United States
Language: English
Volume: 8
Pages: e9469
PII: e9469

Researcher Affiliations

Malacarne, Bruno D
  • Equinova Research Group -Department of Veterinary Clinics and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Cota, Leticia O
  • Equinova Research Group -Department of Veterinary Clinics and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Neto, Antônio C P
  • Equinova Research Group -Department of Veterinary Clinics and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Paz, Cahuê F R
  • Centro Universitário INTA-Uninta, Sobral, Ceará, Brazil.
Dias, Lucas A
  • Equinova Research Group -Department of Veterinary Clinics and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Corrêa, Mayara G
  • Equinova Research Group -Department of Veterinary Clinics and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Carvalho, Armando M
  • Equinova Research Group -Department of Veterinary Clinics and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Faleiros, Rafael R
  • Equinova Research Group -Department of Veterinary Clinics and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Conselho Nacional de Desenvolvimento Cientìfico e Tecnològico -CNPq, Brasília, Brazil.
Xavier, Andressa B S
  • Equinova Research Group -Department of Veterinary Clinics and Surgery, School of Veterinary, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Conflict of Interest Statement

The authors declare there are no competing interests.

References

This article includes 24 references
  1. Bowker RM. Innervation of the equine foot: its importance to the horse and to the clinician.. In: Floyd A, Mansmann R, editors. Equine podiatry. Saunders Elsevier; St Louis: 2007. pp. 76–78.
  2. Bowker RM, Linder K, Van Wulfen KK, Sonea IM. Anatomy of the distal interphalangeal joint of the mature horse: relationships with navicular suspensory ligaments, sensory nerves and neurovascular bundle.. Equine Vet J 1997 Mar;29(2):126-35.
    doi: 10.1111/j.2042-3306.1997.tb01654.xpubmed: 9104562google scholar: lookup
  3. Dau SL, Azevedo MS, De La Corte FD, Brass KE, Gallio M, Ceni F, Lubini BB. Response of three digital anesthetic technics in horses with forelimb hoof lameness.. Arquivo Brasileiro de Medicina Veterinária e Zootecnia 2017;69:793–801.
    doi: 10.1590/1678-4162-9155google scholar: lookup
  4. Dyson SJ. The puzzle of distal interphalangeal joint pain.. Equine Veterinary Education 1998;10:119–125.
    doi: 10.1111/j.2042-3292.1998.tb00862.xgoogle scholar: lookup
  5. Dyson SJ, Kidd L. A comparison of responses to analgesia of the navicular bursa and intra-articular analgesia of the distal interphalangeal joint in 59 horses.. Equine Vet J 1993 Mar;25(2):93-8.
    doi: 10.1111/j.2042-3306.1993.tb02915pubmed: 8467786google scholar: lookup
  6. Dyson S, Murray R, Schramme M, Branch M. Lameness in 46 horses associated with deep digital flexor tendonitis in the digit: diagnosis confirmed with magnetic resonance imaging.. Equine Vet J 2003 Nov;35(7):681-90.
    doi: 10.2746/042516403775696294pubmed: 14649360google scholar: lookup
  7. Easter JE, Watkins JP, Stephens SL, Carter GK, Hague BA, Dutton DW, Honnas CM. Effects of regional anesthesia on experimentally induced coffin joint synovitis.. Proceedings of the annual convention American association of equine practitioners, San Antonio, Texas, USA 26th–29th November; 2000. pp. 214–216.
  8. Gough MR, Mayhew G, Munroe GA. Diffusion of mepivacaine between adjacent synovial structures in the horse. Part 1: forelimb foot and carpus.. Equine Vet J 2002 Jan;34(1):80-4.
    doi: 10.2746/042516402776181097pubmed: 11817556google scholar: lookup
  9. Haussler KK, Behre TH, Hill AE. Mechanical nociceptive thresholds within the pastern region of Tennessee Walking Horses.. Equine Vet J 2008 Jul;40(5):455-9.
    doi: 10.2746/042516408X278166pubmed: 18321808google scholar: lookup
  10. Haussler KK, Erb HN. Mechanical nociceptive thresholds in the axial skeleton of horses.. Equine Vet J 2006 Jan;38(1):70-5.
    doi: 10.2746/042516406775374315pubmed: 16411590google scholar: lookup
  11. Jordana M, Martens A, Duchateau L, Vanderperren K, Saunders J, Oosterlinck M, Pille F. Distal limb desensitisation following analgesia of the digital flexor tendon sheath in horses using four different techniques.. Equine Vet J 2014 Jul;46(4):488-93.
    doi: 10.1111/evj.12186pubmed: 24033590google scholar: lookup
  12. Kaneps AJ. Diagnosis of lameness.. In: Hinchcliff K, Geor R, editors. Equine sports medicine & surgery. Sauders Elsevier; St. Louis: 2014. pp. 239–250.
  13. Keegan KG, Wilson DA, Kreeger JM, Ellersieck MR, Kuo KC, Li Z. Local distribution of mepivacaine after distal interphalangeal joint injection in horses.. Am J Vet Res 1996 Apr;57(4):422-6.
    pubmed: 8712501
  14. Moyer W, Schumacher J, Schumacher J. In: Equine joint injection and regional anesthesia. Moyer W, Schumacher J, Schumacher J, editors. Academic Veterinary Solutions; Chadds Ford: 2011. pp. 12–19.
  15. Patterson-Kane JC, Karikoski NP, McGowan CM. Paradigm shifts in understanding equine laminitis.. Vet J 2018 Jan;231:33-40.
    doi: 10.1016/j.tvjl.2017.11.011pubmed: 29429485google scholar: lookup
  16. Paz CF, Magalhães JF, Mendes HM, Rocha Junior S, Belknap JK, Alves GE, Faleiros RR. Mechanical nociceptive thresholds of dorsal laminae in horses after local anaesthesia of the palmar digital nerves or dorsal branches of the digital nerve.. Vet J 2016 Aug;214:102-8.
    doi: 10.1016/j.tvjl.2016.05.005pubmed: 27387735google scholar: lookup
  17. Pleasant RS, Moll HD, Ley WB, Lessard P, Warnick LD. Intra-articular anesthesia of the distal interphalangeal joint alleviates lameness associated with the navicular bursa in horses.. Vet Surg 1997 Mar-Apr;26(2):137-40.
    doi: 10.1111/j.1532-950x.1997.tb01476.xpubmed: 9068164google scholar: lookup
  18. Sardari K, Kazemi H, Mohri M. Effects of analgesia of the distal interphalangeal joint and navicular bursa on experimental lameness caused by solar pain in horses.. J Vet Med A Physiol Pathol Clin Med 2002 Nov;49(9):478-81.
    doi: 10.1046/j.1439-0442.2002.00482.xpubmed: 12489872google scholar: lookup
  19. Schumacher J, Schramme M. Diagnostic and regional surgical anesthesia of the limbs and axial skeleton.. In: Auer J, Stick J, Kummerle J, Prange T, editors. Equine surgery. Saunders Elsevier; St. Louis: 2018. pp. 1220–1227.
  20. Schumacher J, Schramme MC, Schumacher J, De Graves FJ. Diagnostic analgesia of the equine digit.. Equine Veterinary Education 2013;25:408–421.
    doi: 10.1111/eve.12001google scholar: lookup
  21. Schumacher J, Schumacher J, de Graves F, Steiger R, Schramme M, Smith R, Coker M. A comparison of the effects of two volumes of local analgesic solution in the distal interphalangeal joint of horses with lameness caused by solar toe or solar heel pain.. Equine Vet J 2001 May;33(3):265-8.
    doi: 10.2746/042516401776249778pubmed: 11352348google scholar: lookup
  22. Schumacher J, Steiger R, Schumacher J, de Graves F, Schramme M, Smith R, Coker M. Effects of analgesia of the distal interphalangeal joint or palmar digital nerves on lameness caused by solar pain in horses.. Vet Surg 2000 Jan-Feb;29(1):54-8.
    doi: 10.1111/j.1532-950x.2000.00054.xpubmed: 10653495google scholar: lookup
  23. Taylor PM, Crosignani N, Lopes C, Rosa AC, Luna SP, Puoli Filho JN. Mechanical nociceptive thresholds using four probe configurations in horses.. Vet Anaesth Analg 2016 Jan;43(1):99-108.
    doi: 10.1111/vaa.12274pubmed: 25997162google scholar: lookup
  24. Zarucco L, Driessen B, Scandella M, Cozzi F, Cantile C. Sensory nerve conduction and nociception in the equine lower forelimb during perineural bupivacaine infusion along the palmar nerves.. Can J Vet Res 2010 Oct;74(4):305-13.
    pmc: PMC2949344pubmed: 21197231

Citations

This article has been cited 2 times.
  1. Cota LO, Malacarne BD, Dias LA, Neto ACP, Kneipp MLA, Cavalcante MA, Cunha MSLD, Paz CFR, Carvalho AM, Faleiros RR, Xavier ABDS. Mechanical nociceptive assessment of the equine hoof after navicular bursa anesthetic infiltration validated by bursography.. PLoS One 2022;17(6):e0269532.
    doi: 10.1371/journal.pone.0269532pubmed: 35671268google scholar: lookup
  2. Haussler KK. Pressure Algometry for the Detection of Mechanical Nociceptive Thresholds in Horses.. Animals (Basel) 2020 Nov 24;10(12).
    doi: 10.3390/ani10122195pubmed: 33255216google scholar: lookup
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