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Journal of the American Veterinary Medical Association2015; 247(11); 1309-1318; doi: 10.2460/javma.247.11.1309

Medical treatment of horses with deep digital flexor tendon injuries diagnosed with high-field-strength magnetic resonance imaging: 118 cases (2000-2010).

Abstract: To describe the location and severity of deep digital flexor tendon (DDFT) lesions diagnosed by means of high-field-strength MRI in horses and to identify variables associated with return to activity following medical treatment. Methods: Retrospective case series. Methods: 118 horses. Methods: Medical records of horses with DDFT injury diagnosed with MRI over a 10-year period (2000-2010) and treated medically (intrasynovial administration of corticosteroids and sodium hyaluronan, rest and rehabilitation, or both) were reviewed. History, signalment, use, results of lameness examination and diagnostic local anesthesia, MRI findings, and treatment details were recorded. Outcome was obtained by telephone interview or follow-up examination. Horses were grouped by predictor variables and analyzed with logistic regression to identify significant effects. Results: Overall, of 97 horses available for follow-up (median time to follow-up, 5 years; range, 1 to 12 years), 59 (61%) returned to activity for a mean duration of 22.6 months (median, 18 months; range, 3 to 72 months), with 25 (26%) still sound at follow-up. Of horses with mild, moderate, and severe injury, 21 of 29 (72%), 20 of 36 (56%), and 18 of 32 (56%), respectively, returned to use. Horses treated with intrasynovial corticosteroid injection and 6 months of rest and rehabilitation returned to use for a significantly longer duration than did horses treated without rest. Western performance horses returned to use for a significantly longer duration than did English performance horses. Conclusions: Results of the present study suggested that outcome for horses with DDFT injuries treated medically depended on injury severity, presence of concurrent injury to other structures in the foot, type of activity, and owner compliance with specific treatment recommendations. Although some horses successfully returned to prior activity, additional treatment options are needed to improve outcome in horses with severe injuries and to improve long-term prognosis.
Publication Date: 2015-11-26 PubMed ID: 26594815DOI: 10.2460/javma.247.11.1309Google Scholar: Lookup
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  • Journal Article

Summary

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The research examines medical treatments for deep digital flexor tendon (DDFT) injuries in horses as diagnosed with MRI, focusing on the effectiveness of these treatments in terms of the horses’ return to activity.

Objective and Methodology

The study’s objective was to identify the location and severity of DDFT injuries in horses using high-field-strength MRI and to determine factors associated with the horse’s return to activity following medical treatment. The study adopted a retrospective case series approach and went through medical records of 118 horses over a span of a decade (2000-2010). The horses had DDFT injuries diagnosed with MRI and were given medical treatment that involved intrasynovial administration of corticosteroids, sodium hyaluronan, rest, rehabilitation, or combinations of these.

  • In terms of methodology, the researchers recorded various factors including the horses’ history, signalment, use, results of lameness examination, local anesthesia, MRI findings, and treatment details.
  • The outcome was obtained via telephone interviews or follow up examination, and the horses were grouped by predictor variables and analyzed with logistic regression to identify significant effects.

Results

  • Out of 97 horses available for a follow-up, 61% reportedly returned to activity for an average duration of about 22.6 months.
  • In horses with varying injury levels – mild, moderate, and severe – it was found that 72%, 56%, and 56% respectively returned to use.
  • Horses treated with intrasynovial corticosteroid injection and provided with a 6-month rest and rehabilitation period had significantly longer usage than those not given rest.
  • Interestingly, Western performance horses showed significantly longer usage upon return than their English performance counterparts.

Conclusions

The study’s findings suggested that outcomes for horses with DDFT injuries who were medically treated depended greatly on the injury severity, any concurrent injury to other structures in the foot, the type of activity the horse engaged in, and the owner’s compliance with specific treatment recommendations. While some horses successfully returned to prior activity, the conclusions underscored the need for more treatment options, especially in cases of severe injuries, to improve the long-term prognosis.

Cite This Article

APA
Lutter JD, Schneider RK, Sampson SN, Cary JA, Roberts GD, Vahl CI. (2015). Medical treatment of horses with deep digital flexor tendon injuries diagnosed with high-field-strength magnetic resonance imaging: 118 cases (2000-2010). J Am Vet Med Assoc, 247(11), 1309-1318. https://doi.org/10.2460/javma.247.11.1309

Publication

ISSN: 1943-569X
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 247
Issue: 11
Pages: 1309-1318

Researcher Affiliations

Lutter, John D
    Schneider, Robert K
      Sampson, Sarah N
        Cary, Julie A
          Roberts, Greg D
            Vahl, Christopher I

              MeSH Terms

              • Animals
              • Anti-Inflammatory Agents / administration & dosage
              • Anti-Inflammatory Agents / therapeutic use
              • Drug Therapy, Combination
              • Horse Diseases / diagnosis
              • Horse Diseases / therapy
              • Horses / injuries
              • Hyaluronic Acid / administration & dosage
              • Hyaluronic Acid / therapeutic use
              • Magnetic Resonance Imaging / methods
              • Magnetic Resonance Imaging / veterinary
              • Methylprednisolone / administration & dosage
              • Methylprednisolone / analogs & derivatives
              • Methylprednisolone / therapeutic use
              • Methylprednisolone Acetate
              • Retrospective Studies
              • Tendon Injuries / diagnosis
              • Tendon Injuries / veterinary
              • Viscosupplements / administration & dosage
              • Viscosupplements / therapeutic use

              Citations

              This article has been cited 6 times.
              1. Scharf A, Acutt E, Bills K, Werpy N. Magnetic resonance imaging for diagnosing and managing deep digital flexor tendinopathy in equine athletes: Insights, advances and future directions. Equine Vet J 2025 Sep;57(5):1183-1203.
                doi: 10.1111/evj.14508pubmed: 40314097google scholar: lookup
              2. Quam VG, Belacic ZA, Long S, Rice HC, Dhar MS, Durgam S. Equine bone marrow MSC-derived extracellular vesicles mitigate the inflammatory effects of interleukin-1β on navicular tissues in vitro. Equine Vet J 2025 Jan;57(1):232-242.
                doi: 10.1111/evj.14090pubmed: 38587145google scholar: lookup
              3. McParland TJ, Horne CR, Robertson JB, Schnabel LV, Nelson NC. Alterations to the synovial invaginations of the navicular bone are associated with pathology of both the navicular apparatus and distal interphalangeal joint when evaluated using high field MRI. Vet Radiol Ultrasound 2023 Jan;64(1):9-17.
                doi: 10.1111/vru.13140pubmed: 35969227google scholar: lookup
              4. Quam VG, Altmann NN, Brokken MT, Durgam SS. Zonal characterization and differential trilineage potentials of equine intrasynovial deep digital flexor tendon-derived cells. BMC Vet Res 2021 Apr 1;17(1):138.
                doi: 10.1186/s12917-021-02793-1pubmed: 33794882google scholar: lookup
              5. Sullivan SN, Altmann NN, Brokken MT, Durgam SS. In vitro Effects of Methylprednisolone Acetate on Equine Deep Digital Flexor Tendon-Derived Cells. Front Vet Sci 2020;7:486.
                doi: 10.3389/fvets.2020.00486pubmed: 32851046google scholar: lookup
              6. Kornicka-Garbowska K, Pędziwiatr R, Woźniak P, Kucharczyk K, Marycz K. Microvesicles isolated from 5-azacytidine-and-resveratrol-treated mesenchymal stem cells for the treatment of suspensory ligament injury in horse-a case report. Stem Cell Res Ther 2019 Dec 18;10(1):394.
                doi: 10.1186/s13287-019-1469-5pubmed: 31852535google scholar: lookup