Omneity® Pellets
All-In-One Vitamin & Mineral Pellet
Mitochondrial control region and 12S rRNA variation in Przewalski’s horse (Equus przewalskii).
Abstract: Variation in the control region and the 12S rRNA gene of all surviving mitochondrial lineages of Przewalski's horse was investigated. Variation is low despite the present day population being descended from 13 individuals probably representing animals from three different regions of its range. Phylogenetic comparison of these sequences, with sequences for the domestic horse, does not resolve the ancestral status of either horse.
Publication Date: 1999-01-12 PubMed ID: 9883508DOI: 10.1046/j.1365-2052.1998.296380.xGoogle Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The study investigates the variation in the control region and the 12S rRNA gene in Przewalski’s horse populations, revealing low variation despite their descendence from 13 different individuals. A comparison of these sequences with domestic horses doesn’t ascertain the ancestral status of either horse type.
Investigation of Mitochondrial Variation in Przewalski’s Horse
The main focus of this research article lies in the exploration of variation levels in the mitochondrial control region and 12S rRNA gene of Przewalski’s horse, a rare and endangered species.
- The control region and the 12S rRNA gene are both significant components of mitochondrial DNA, essential for understanding genetic diversity and lineage.
- The researchers analysed the existing surviving mitochondrial lineages of Przewalski’s horse. This involved studying all the horses descended from 13 known individuals.
- Despite the diverse genetic background, the findings reveal low levels of variation in the control region and 12S rRNA gene within the Przewalski’s horse population.
Phylogenetic Comparison with Domestic Horse
Furthering their research, the scientists made a phylogenetic comparison between the genetic sequences of Przewalski’s horse and the domestic horse.
- Phylogenetics is a branch of biology that reconstructs evolutionary relationships based on genetic data. It aids in determining ancestral relationships between species.
- Contrary to typical expectations in such a study, the comparison didn’t result in a clear determination as to which horse type may be considered ancestrally superior or primary.
- This inconclusiveness of ancestral status indicates that more research will be needed to trace the exact relationship between the domestic horse and Przewalski’s horse.
Implications of the Study
This study, despite its inconclusive results regarding the ancestral lineage, provides valuable insights about the genetic makeup of Przewalski’s horse.
- The findings about low genetic variation among Przewalski’s horses might raise concerns about the population’s resilience to disease or adaptability to environmental change.
- This research contributes to the broader field of genetic study on endangered species, which is essential for future conservation efforts.
- The results might prompt further studies regarding the breed’s susceptibility to disease and survival adaptability to identify potential threats and mitigate risks.
Cite This Article
APA
Oakenfull EA, Ryder OA.
(1999).
Mitochondrial control region and 12S rRNA variation in Przewalski’s horse (Equus przewalskii).
Anim Genet, 29(6), 456-459.
https://doi.org/10.1046/j.1365-2052.1998.296380.x Publication
Researcher Affiliations
- Center for Reproduction of Endangered Species, Zoological Society of San Diego, CA 92112, USA.
MeSH Terms
- Animals
- DNA, Mitochondrial / genetics
- Female
- Genetic Variation
- Horses / genetics
- Male
- Pedigree
- RNA, Ribosomal / genetics
Citations
This article has been cited 13 times.- Piras FM, Cappelletti E, Abdelgadir WA, Salamon G, Vignati S, Santagostino M, Sola L, Nergadze SG, Giulotto E. A Satellite-Free Centromere in Equus przewalskii Chromosome 10. Int J Mol Sci 2023 Feb 18;24(4).
- Turghan MA, Jiang Z, Niu Z. An Update on Status and Conservation of the Przewalski's Horse (Equus ferus przewalskii): Captive Breeding and Reintroduction Projects. Animals (Basel) 2022 Nov 15;12(22).
- Tang Y, Liu G, Zhao S, Li K, Zhang D, Liu S, Hu D. Major Histocompatibility Complex (MHC) Diversity of the Reintroduction Populations of Endangered Przewalski's Horse. Genes (Basel) 2022 May 23;13(5).
- Bennett EA, Champlot S, Peters J, Arbuckle BS, Guimaraes S, Pruvost M, Bar-David S, Davis SJM, Gautier M, Kaczensky P, Kuehn R, Mashkour M, Morales-Muñiz A, Pucher E, Tournepiche JF, Uerpmann HP, Bălăşescu A, Germonpré M, Gündem CY, Hemami MR, Moullé PE, Ötzan A, Uerpmann M, Walzer C, Grange T, Geigl EM. Taming the late Quaternary phylogeography of the Eurasiatic wild ass through ancient and modern DNA. PLoS One 2017;12(4):e0174216.
- Der Sarkissian C, Ermini L, Schubert M, Yang MA, Librado P, Fumagalli M, Jónsson H, Bar-Gal GK, Albrechtsen A, Vieira FG, Petersen B, Ginolhac A, Seguin-Orlando A, Magnussen K, Fages A, Gamba C, Lorente-Galdos B, Polani S, Steiner C, Neuditschko M, Jagannathan V, Feh C, Greenblatt CL, Ludwig A, Abramson NI, Zimmermann W, Schafberg R, Tikhonov A, Sicheritz-Ponten T, Willerslev E, Marques-Bonet T, Ryder OA, McCue M, Rieder S, Leeb T, Slatkin M, Orlando L. Evolutionary Genomics and Conservation of the Endangered Przewalski's Horse. Curr Biol 2015 Oct 5;25(19):2577-83.
- Han H, Zhang Q, Gao K, Yue X, Zhang T, Dang R, Lan X, Chen H, Lei C. Y-Single Nucleotide Polymorphisms Diversity in Chinese Indigenous Horse. Asian-Australas J Anim Sci 2015 Aug;28(8):1066-74.
- Vilstrup JT, Seguin-Orlando A, Stiller M, Ginolhac A, Raghavan M, Nielsen SC, Weinstock J, Froese D, Vasiliev SK, Ovodov ND, Clary J, Helgen KM, Fleischer RC, Cooper A, Shapiro B, Orlando L. Mitochondrial phylogenomics of modern and ancient equids. PLoS One 2013;8(2):e55950.
- Achilli A, Olivieri A, Soares P, Lancioni H, Hooshiar Kashani B, Perego UA, Nergadze SG, Carossa V, Santagostino M, Capomaccio S, Felicetti M, Al-Achkar W, Penedo MC, Verini-Supplizi A, Houshmand M, Woodward SR, Semino O, Silvestrelli M, Giulotto E, Pereira L, Bandelt HJ, Torroni A. Mitochondrial genomes from modern horses reveal the major haplogroups that underwent domestication. Proc Natl Acad Sci U S A 2012 Feb 14;109(7):2449-54.
- Lippold S, Knapp M, Kuznetsova T, Leonard JA, Benecke N, Ludwig A, Rasmussen M, Cooper A, Weinstock J, Willerslev E, Shapiro B, Hofreiter M. Discovery of lost diversity of paternal horse lineages using ancient DNA. Nat Commun 2011 Aug 23;2:450.
- Goto H, Ryder OA, Fisher AR, Schultz B, Kosakovsky Pond SL, Nekrutenko A, Makova KD. A massively parallel sequencing approach uncovers ancient origins and high genetic variability of endangered Przewalski's horses. Genome Biol Evol 2011;3:1096-106.
- Orlando L, Eisenmann V, Reynier F, Sondaar P, Hänni C. Morphological convergence in Hippidion and Equus (Amerhippus) South American equids elucidated by ancient DNA analysis. J Mol Evol 2003;57 Suppl 1:S29-40.
- Burg TM, Lomax J, Almond R, Brooke Mde L, Amos W. Unravelling dispersal patterns in an expanding population of a highly mobile seabird, the northern fulmar (Fulmarus glacialis). Proc Biol Sci 2003 May 7;270(1518):979-84.
- Jansen T, Forster P, Levine MA, Oelke H, Hurles M, Renfrew C, Weber J, Olek K. Mitochondrial DNA and the origins of the domestic horse. Proc Natl Acad Sci U S A 2002 Aug 6;99(16):10905-10.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
