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The Veterinary clinics of North America. Equine practice1990; 6(2); 419-431; doi: 10.1016/s0749-0739(17)30549-7

Molds, mycotoxins, and mycotoxicosis.

Abstract: Interest in mycotoxins and mycotoxicosis in humans and animals has greatly increased in recent years. Horses have long been considered very susceptible to molds. The signs, treatment, and prevention of several conditions, such as leukoencephalomalacia, aflatoxicosis, ergotism, fescue toxicity, slobbering disease, ryegrass staggers, and moldy sweet clover disease, are discussed.
Publication Date: 1990-08-01 PubMed ID: 2202500DOI: 10.1016/s0749-0739(17)30549-7Google Scholar: Lookup
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Summary

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This research study focuses on the growing concern around mycotoxins, toxic substances produced by molds, and mycotoxicosis, the illnesses caused by these toxins, particularly in horses. It further discusses the symptoms, treatment, and prevention of several mold-related conditions.

Understanding Mycotoxins and Mycotoxicosis

  • This research emphasizes the increased concern about mycotoxins and mycotoxicosis in animals, especially horses. Mycotoxins are toxic substances created by molds, and mycotoxicosis refers to the illnesses they cause.
  • Horses have always been considered highly susceptible to mold-related diseases. Different varieties of molds can lead to diverse conditions, with varying symptoms, severity, and treatment.
  • The study not only highlights the problem, but it aims to contribute towards solutions through effective treatments and prevention methods.

Leukoencephalomalacia, Aflatoxicosis, and Other Conditions

  • Leukoencephalomalacia is a neurological disease in horses caused by the ingestion of mycotoxins, specifically fumonisin B1. It affects the brain and can lead to symptoms like disorientation, blindness, and other neurological signs.
  • Aflatoxicosis refers to poisoning that results from ingestion of aflatoxins, another form of mycotoxins. It can affect various organs, primarily the liver, and cause weight loss, jaundice, and even death.
  • The research also covers ergotism (characterized by muscle pain, fever, seizures), fescue toxicity (caused by the consumption of tall fescue infected by a specific fungus), slobbering disease, ryegrass staggers (a neurological condition triggered by toxins present in perennial ryegrass), and moldy sweet clover disease, which induces bleeding disorders.

Signs, Treatment, and Prevention

  • The signs of these diseases vary depending on the specific condition. They include symptoms like weight loss, blindness, fever, seizures, and excessive salivation. Identifying these symptoms promptly is vital as some of these conditions can be fatal without early intervention.
  • Treatment involves removing the source of the mold or mycotoxin. This primarily includes a change in feed if it’s determined to be the source of the mycotoxin. More serious cases might also require medicinal interventions.
  • Preventive strategies focus on minimizing exposure to mycotoxins in the first place. This can be achieved through proper storage of horse feed and routine checks for evidence of mold in barns and stables.

Cite This Article

APA
Hintz HF. (1990). Molds, mycotoxins, and mycotoxicosis. Vet Clin North Am Equine Pract, 6(2), 419-431. https://doi.org/10.1016/s0749-0739(17)30549-7

Publication

ISSN: 0749-0739
NlmUniqueID: 8511904
Country: United States
Language: English
Volume: 6
Issue: 2
Pages: 419-431

Researcher Affiliations

Hintz, H F
  • Department of Animal Science, New York State College of Agriculture, Cornell University, Ithaca.

MeSH Terms

  • Aflatoxins / poisoning
  • Animals
  • Encephalomalacia / etiology
  • Encephalomalacia / veterinary
  • Ergotism / etiology
  • Ergotism / veterinary
  • Horse Diseases / etiology
  • Horses
  • Mycotoxicosis / etiology
  • Mycotoxicosis / veterinary
  • Poaceae

References

This article includes 58 references

Citations

This article has been cited 1 times.
  1. Froquet R, Arnold F, Batina P, Parent-Massin D. Do trichothecenes reduce viability of circulating blood cells and modify haemostasis parameters?. Mycopathologia 2003;156(4):349-56.