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Annals of tropical medicine and parasitology1963; 57; 415-427; doi: 10.1080/00034983.1963.11686194

Natural and Experimental Infection of Egyptian Equines with West Nile Virus.

Abstract: No abstract available
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Publication Date: 1963-12-01 PubMed ID: 14101930DOI: 10.1080/00034983.1963.11686194Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article explores the occurrence and impact of West Nile Virus in equine populations in Egypt. It investigates the role of horses in the transmission and maintenance of the virus in nature, as well as records the isolated case of equine encephalitis resulting from the virus.

Research Context and Background

  • The article starts by outlining the scope and impact of West Nile fever, which is similar to dengue and present in much of Africa, the Middle East, and India.
  • It highlights that the current understanding of the virus’s epidemiology and ecology comes mainly from studies done in Egypt and Israel.
  • The researchers explain that the primary infection cycle involves mosquitoes of the Cu/lex species and various types of birds, with humans and other vertebrates being infected secondarily.
  • Hay discuss that even though secondary infections usually do not contribute to the virus’s spread (referred to as ‘dead end’), the role of non-avian vertebrates has not been adequately studied.

Role of Horses in West Nile Virus Transmission

  • The study notices that the serological surveys carried out previously in the Nile delta show a wide range of vertebrates getting infected. Still, horses show the highest incidence of antibody.
  • This is significant because horses are known to host several arthropod-borne viruses like the eastern, western, Venezuelan, and Japanese encephalitis viruses.
  • Therefore, the researchers felt it was necessary to evaluate the importance of horses in the natural history of West Nile fever.

Research Findings and Experiments

  • The research gives an account of the incidence and distribution of West Nile virus infection in the horse populations of the Nile delta and Upper Egypt.
  • It presents the isolation of the West Nile virus from a case of equine encephalitis in Upper Egypt.
  • The authors summarize the experiments that were designed to clarify the role of horses in the cyclical passage and maintenance of the virus in nature.

Cite This Article

APA
SCHMIDT JR, ELMANSOURY HK. (1963). Natural and Experimental Infection of Egyptian Equines with West Nile Virus. Ann Trop Med Parasitol, 57, 415-427. https://doi.org/10.1080/00034983.1963.11686194

Publication

Annals of tropical medicine and parasitology
ISSN: 0003-4983
NlmUniqueID: 2985178R
Country: England
Language: English
Volume: 57
Pages: 415-427

Researcher Affiliations

SCHMIDT, J R
    ELMANSOURY, H K

      MeSH Terms

      • Animals
      • Complement Fixation Tests
      • Culicidae
      • Egypt
      • Encephalitis Viruses
      • Encephalitis, Arbovirus
      • Encephalomyelitis
      • Encephalomyelitis, Equine
      • Epidemiology
      • Hemagglutination Inhibition Tests
      • Horse Diseases
      • Horses
      • Insect Vectors
      • Neutralization Tests
      • Perissodactyla
      • Research
      • Serologic Tests
      • West Nile virus
      • Zoonoses

      Citations

      This article has been cited 23 times.
      1. Fang Y, Khater EIM, Xue JB, Ghallab EHS, Li YY, Jiang TG, Li SZ. Epidemiology of Mosquito-Borne Viruses in Egypt: A Systematic Review. Viruses 2022 Jul 20;14(7).
        doi: 10.3390/v14071577pubmed: 35891557google scholar: lookup
      2. Mencattelli G, Ndione MHD, Rosà R, Marini G, Diagne CT, Diagne MM, Fall G, Faye O, Diallo M, Faye O, Savini G, Rizzoli A. Epidemiology of West Nile virus in Africa: An underestimated threat. PLoS Negl Trop Dis 2022 Jan;16(1):e0010075.
        doi: 10.1371/journal.pntd.0010075pubmed: 35007285google scholar: lookup
      3. Selim A, Megahed A, Kandeel S, Alouffi A, Almutairi MM. West Nile virus seroprevalence and associated risk factors among horses in Egypt. Sci Rep 2021 Oct 22;11(1):20932.
        doi: 10.1038/s41598-021-00449-6pubmed: 34686730google scholar: lookup
      4. Humphreys JM, Pelzel-McCluskey AM, Cohnstaedt LW, McGregor BL, Hanley KA, Hudson AR, Young KI, Peck D, Rodriguez LL, Peters DPC. Integrating Spatiotemporal Epidemiology, Eco-Phylogenetics, and Distributional Ecology to Assess West Nile Disease Risk in Horses. Viruses 2021 Sep 12;13(9).
        doi: 10.3390/v13091811pubmed: 34578392google scholar: lookup
      5. Olufemi OT, Barba M, Daly JM. A Scoping Review of West Nile Virus Seroprevalence Studies among African Equids. Pathogens 2021 Jul 15;10(7).
        doi: 10.3390/pathogens10070899pubmed: 34358049google scholar: lookup
      6. Keyel AC, Elison Timm O, Backenson PB, Prussing C, Quinones S, McDonough KA, Vuille M, Conn JE, Armstrong PM, Andreadis TG, Kramer LD. Seasonal temperatures and hydrological conditions improve the prediction of West Nile virus infection rates in Culex mosquitoes and human case counts in New York and Connecticut. PLoS One 2019;14(6):e0217854.
        doi: 10.1371/journal.pone.0217854pubmed: 31158250google scholar: lookup
      7. Kumar B, Manuja A, Gulati BR, Virmani N, Tripathi BN. Zoonotic Viral Diseases of Equines and Their Impact on Human and Animal Health. Open Virol J 2018;12:80-98.
        doi: 10.2174/1874357901812010080pubmed: 30288197google scholar: lookup
      8. Aharonson-Raz K, Lichter-Peled A, Tal S, Gelman B, Cohen D, Klement E, Steinman A. Spatial and temporal distribution of West Nile virus in horses in Israel (1997-2013)--from endemic to epidemics. PLoS One 2014;9(11):e113149.
        doi: 10.1371/journal.pone.0113149pubmed: 25402217google scholar: lookup
      9. Lim SM, Koraka P, van Boheemen S, Roose JM, Jaarsma D, van de Vijver DA, Osterhaus AD, Martina BE. Characterization of the mouse neuroinvasiveness of selected European strains of West Nile virus. PLoS One 2013;8(9):e74575.
        doi: 10.1371/journal.pone.0074575pubmed: 24058590google scholar: lookup
      10. Angenvoort J, Brault AC, Bowen RA, Groschup MH. West Nile viral infection of equids. Vet Microbiol 2013 Nov 29;167(1-2):168-80.
        doi: 10.1016/j.vetmic.2013.08.013pubmed: 24035480google scholar: lookup
      11. Ledermann JP, Lorono-Pino MA, Ellis C, Saxton-Shaw KD, Blitvich BJ, Beaty BJ, Bowen RA, Powers AM. Evaluation of widely used diagnostic tests to detect West Nile virus infections in horses previously infected with St. Louis encephalitis virus or dengue virus type 2. Clin Vaccine Immunol 2011 Apr;18(4):580-7.
        doi: 10.1128/CVI.00201-10pubmed: 21346058google scholar: lookup
      12. Weese JS, Baird JD, DeLay J, Kenney DG, Staempfli HR, Viel L, Parent J, Smith-Maxie L, Poma R. West Nile virus encephalomyelitis in horses in Ontario: 28 cases. Can Vet J 2003 Jun;44(6):469-73.
        pubmed: 12839240
      13. Autorino GL, Battisti A, Deubel V, Ferrari G, Forletta R, Giovannini A, Lelli R, Murri S, Scicluna MT. West Nile virus epidemic in horses, Tuscany region, Italy. Emerg Infect Dis 2002 Dec;8(12):1372-8.
        doi: 10.3201/eid0812.020234pubmed: 12498650google scholar: lookup
      14. Durand B, Chevalier V, Pouillot R, Labie J, Marendat I, Murgue B, Zeller H, Zientara S. West Nile virus outbreak in horses, southern France, 2000: results of a serosurvey. Emerg Infect Dis 2002 Aug;8(8):777-82.
        doi: 10.3201/eid0808.010486pubmed: 12141961google scholar: lookup
      15. Bunning ML, Bowen RA, Cropp CB, Sullivan KG, Davis BS, Komar N, Godsey MS, Baker D, Hettler DL, Holmes DA, Biggerstaff BJ, Mitchell CJ. Experimental infection of horses with West Nile virus. Emerg Infect Dis 2002 Apr;8(4):380-6.
        doi: 10.3201/eid0804.010239pubmed: 11971771google scholar: lookup
      16. Ostlund EN, Crom RL, Pedersen DD, Johnson DJ, Williams WO, Schmitt BJ. Equine West Nile encephalitis, United States. Emerg Infect Dis 2001 Jul-Aug;7(4):665-9.
        doi: 10.3201/eid0704.010412pubmed: 11589171google scholar: lookup
      17. Komar N, Panella NA, Boyce E. Exposure of domestic mammals to West Nile virus during an outbreak of human encephalitis, New York City, 1999. Emerg Infect Dis 2001 Jul-Aug;7(4):736-8.
        doi: 10.3201/eid0704.010424pubmed: 11585540google scholar: lookup
      18. Murgue B, Murri S, Zientara S, Durand B, Durand JP, Zeller H. West Nile outbreak in horses in southern France, 2000: the return after 35 years. Emerg Infect Dis 2001 Jul-Aug;7(4):692-6.
        doi: 10.3201/eid0704.010417pubmed: 11585534google scholar: lookup
      19. Abbas I, Ahmed F, Muqaddas H, Alberti A, Varcasia A, Sedda L. Epidemiology and surveillance of West Nile virus in the Mediterranean Basin during 2010-2023: A systematic review. Curr Res Parasitol Vector Borne Dis 2025;7:100277.
        doi: 10.1016/j.crpvbd.2025.100277pubmed: 40586111google scholar: lookup
      20. Naveed A, Eertink LG, Wang D, Li F. Lessons Learned from West Nile Virus Infection:Vaccinations in Equines and Their Implications for One Health Approaches. Viruses 2024 May 14;16(5).
        doi: 10.3390/v16050781pubmed: 38793662google scholar: lookup
      21. Rusenova N, Rusenov A, Chervenkov M, Sirakov I. Seroprevalence of West Nile Virus among Equids in Bulgaria in 2022 and Assessment of Some Risk Factors. Vet Sci 2024 May 9;11(5).
        doi: 10.3390/vetsci11050209pubmed: 38787181google scholar: lookup
      22. Schwarz ER, Long MT. Comparison of West Nile Virus Disease in Humans and Horses: Exploiting Similarities for Enhancing Syndromic Surveillance. Viruses 2023 May 24;15(6).
        doi: 10.3390/v15061230pubmed: 37376530google scholar: lookup
      23. Burt FJ, Grobbelaar AA, Leman PA, Anthony FS, Gibson GV, Swanepoel R. Phylogenetic relationships of southern African West Nile virus isolates. Emerg Infect Dis 2002 Aug;8(8):820-6.
        doi: 10.3201/eid0808.020027pubmed: 12141968google scholar: lookup
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