FREE SHIPPING over $40
OVER 9000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Home / Equine Research Bank / Radiology / Needle aspiration lung biopsy: reevaluation of the blood pat...
Radiology1995; 196(1); 183-186; doi: 10.1148/radiology.196.1.7784564

Needle aspiration lung biopsy: reevaluation of the blood patch technique in an equine model.

Abstract: To reexamine the blood patch technique in a laboratory model of lung biopsy free of confounding clinical variables. Methods: An equine model of lung biopsy was developed with an excised lobe connected to an insufflation bulb and pressure monitor. Patched and control unpatched punctures were made in the lung surface, and the pressure within the lung was raised to the maximum achievable. Whether air leakage from the puncture sites could be induced was determined and, if so, at what pressure it occurred. Results: At statistical analysis with the Kaplan-Meier test and the Cox proportional hazards regression model, the difference between failure of the patched and unpatched punctures was statistically significant (P < .0001). Conclusions: The blood patch technique is effective in the laboratory setting and deserves reevaluation in a clinical series with updated biopsy techniques.
Get Full Text
Publication Date: 1995-07-01 PubMed ID: 7784564DOI: 10.1148/radiology.196.1.7784564Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research evaluates the effectiveness of the blood patch technique during a lung biopsy in an equine model, showing a significant difference in the success rate when compared to unpatched punctures. The blood patch technique was found to be effective in this experimental setting, suggesting a need for reevaluation in a clinical context with updated biopsy procedures.

Experimental Method

  • The researchers created an equine model of lung biopsy by using an excised lobe attached to an insufflation bulb and pressure monitor. The insufflation bulb was used to increase pressure within the lung.
  • They then made punctures on the lung surface, both with a blood patch (patched) and without (control unpatched).
  • The pressure within the lung was increased to the maximum achievable level.
  • The goal of the experiment was to determine if air leakage could be induced from the puncture sites and at what pressure this would occur.

Results

  • Statistical analysis was performed using the Kaplan-Meier test and the Cox proportional hazards regression model. Both of these tests are utilized in medical research to measure survival rates and odds of particular events happening respectively.
  • The results revealed a statistically significant difference between the failure rates of the patched and unpatched punctures (P < .0001).

Conclusions

  • Based on the laboratory findings, the blood patch technique was found to be effective within an experimental setting.
  • Given its effectiveness, the researchers suggest reevaluating the blood patch technique in a clinical setting, especially with regard to updated lung biopsy procedures.

Cite This Article

APA
Moore EH, Shelton DK, Wisner ER, Richardson ML, Bishop DM, Brock JM. (1995). Needle aspiration lung biopsy: reevaluation of the blood patch technique in an equine model. Radiology, 196(1), 183-186. https://doi.org/10.1148/radiology.196.1.7784564

Publication

Radiology
ISSN: 0033-8419
NlmUniqueID: 0401260
Country: United States
Language: English
Volume: 196
Issue: 1
Pages: 183-186

Researcher Affiliations

Moore, E H
  • Department of Radiology, University of California Davis Medical Center, Sacramento 95817, USA.
Shelton, D K
    Wisner, E R
      Richardson, M L
        Bishop, D M
          Brock, J M

            MeSH Terms

            • Animals
            • Biopsy, Needle / methods
            • Horses
            • In Vitro Techniques
            • Lung / pathology

            Citations

            This article has been cited 9 times.
            1. Peng B, Deng Z, Wang Y, Xu S, Luo D, Du Z, Liu L, Hu Y, Ren Y. The risk of immediate pneumothorax after CT-guided lung needle biopsy: pleural tail sign as a novel factor. Quant Imaging Med Surg 2023 Feb 1;13(2):707-719.
              doi: 10.21037/qims-22-474pubmed: 36819288google scholar: lookup
            2. Shiekh Y, Haseeb WA, Feroz I, Shaheen FA, Gojwari TA, Choh NA. Evaluation of various patient-, lesion-, and procedure-related factors on the occurrence of pneumothorax as a complication of CT-guided percutaneous transthoracic needle biopsy. Pol J Radiol 2019;84:e73-e79.
              doi: 10.5114/pjr.2019.82837pubmed: 31019598google scholar: lookup
            3. Maybody M, Muallem N, Brown KT, Moskowitz CS, Hsu M, Zenobi CL, Jihad M, Getrajdman GI, Sofocleous CT, Erinjeri JP, Covey AM, Brody LA, Yarmohammadi H, Deipolyi AR, Bryce Y, Alago W, Siegelbaum RH, Durack JC, Gonzalez-Aguirre AJ, Ziv E, Boas FE, Solomon SB. Autologous Blood Patch Injection versus Hydrogel Plug in CT-guided Lung Biopsy: A Prospective Randomized Trial. Radiology 2019 Feb;290(2):547-554.
              doi: 10.1148/radiol.2018181140pubmed: 30480487google scholar: lookup
            4. Ahrar JU, Gupta S, Ensor JE, Mahvash A, Sabir SH, Steele JR, McRae SE, Avritscher R, Huang SY, Odisio BC, Murthy R, Ahrar K, Wallace MJ, Tam AL. Efficacy of a Self-expanding Tract Sealant Device in the Reduction of Pneumothorax and Chest Tube Placement Rates After Percutaneous Lung Biopsy: A Matched Controlled Study Using Propensity Score Analysis. Cardiovasc Intervent Radiol 2017 Feb;40(2):270-276.
              doi: 10.1007/s00270-016-1489-9pubmed: 27826786google scholar: lookup
            5. Billich C, Muche R, Brenner G, Schmidt SA, Krüger S, Brambs HJ, Pauls S. CT-guided lung biopsy: incidence of pneumothorax after instillation of NaCl into the biopsy track. Eur Radiol 2008 Jun;18(6):1146-52.
              doi: 10.1007/s00330-008-0872-6pubmed: 18270713google scholar: lookup
            6. Manhire A, Charig M, Clelland C, Gleeson F, Miller R, Moss H, Pointon K, Richardson C, Sawicka E. Guidelines for radiologically guided lung biopsy. Thorax 2003 Nov;58(11):920-36.
              doi: 10.1136/thorax.58.11.920pubmed: 14586042google scholar: lookup
            7. Chakraborty P. Parenchymal blood patching in percutaneous computed tomography-guided lung biopsy: A retrospective analysis of pneumothorax management. Lung India 2025 Nov 1;42(6):510-513.
              doi: 10.4103/lungindia.lungindia_130_25pubmed: 41129573google scholar: lookup
            8. Naser-Tavakolian K, Clifton M, Mahmoud A, Gupta A. Is the BioSentry Tract Sealant System Effective in Reducing the Pneumothorax Rate After CT-Guided Transthoracic Lung Biopsy With an 18G Biopsy Needle?. Cureus 2024 Oct;16(10):e71078.
              doi: 10.7759/cureus.71078pubmed: 39512979google scholar: lookup
            9. Li T, Zhang Q, Li W, Liu Y. Autologous blood patch intraparenchymal injection reduces the incidence of pneumothorax and the need for chest tube placement following CT-guided lung biopsy: a systematic review and meta-analysis. Eur J Med Res 2024 Feb 9;29(1):108.
              doi: 10.1186/s40001-024-01707-9pubmed: 38336678google scholar: lookup
            Subscribe to our newsletter
            Join 99,383 horse owners like you who receive our email updates on horse health and nutrition.