FREE SHIPPING over $40
OVER 9000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Home / Equine Research Bank / Mem Inst Oswaldo Cruz / Neutralising antibodies for Mayaro virus in Pantanal, Brazil...
Memorias do Instituto Oswaldo Cruz2015; 110(1); 125-133; doi: 10.1590/0074-02760140383

Neutralising antibodies for Mayaro virus in Pantanal, Brazil.

Abstract: The Pantanal hosts diverse wildlife species and therefore is a hotspot for arbovirus studies in South America. A serosurvey for Mayaro virus (MAYV), eastern (EEEV), western (WEEV) and Venezuelan (VEEV) equine encephalitis viruses was conducted with 237 sheep, 87 free-ranging caimans and 748 equids, including 37 collected from a ranch where a neurologic disorder outbreak had been recently reported. Sera were tested for specific viral antibodies using plaque-reduction neutralisation test. From a total of 748 equids, of which 264 were immunised with vaccine composed of EEEV and WEEV and 484 had no history of immunisation, 10 (1.3%) were seropositive for MAYV and two (0.3%) for VEEV using criteria of a ≥ 4-fold antibody titre difference. Among the 484 equids without history of immunisation, 48 (9.9%) were seropositive for EEEV and four (0.8%) for WEEV using the same criteria. Among the sheep, five were sero- positive for equine encephalitis alphaviruses, with one (0.4%) for EEEV, one (0.4%) for WEEV and three (1.3%) for VEEV. Regarding free-ranging caimans, one (1.1%) and three (3.4%), respectively, had low titres for neutralising antibodies to VEEV and undetermined alphaviruses. The neurological disorder outbreak could not be linked to the alphaviruses tested. Our findings represent strong evidence that MAYV and all equine encephalitis alphaviruses circulated in the Pantanal.
Get Full Text
Publication Date: 2015-02-03 PubMed ID: 25742272PubMed Central: PMC4371226DOI: 10.1590/0074-02760140383Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research examined the presence of neutralizing antibodies for various viruses, including the Mayaro virus, in different animal populations in the Pantanal region of Brazil. The results indicate that these viruses have indeed been circulating in the area.

Study Design and Participants

  • The researchers conducted a serosurvey, which is a test of blood serum from a group of individuals to determine the prevalence of an antibody against a specific virus.
  • The study involved 237 sheep, 87 free-ranging caimans (a type of reptile), and 748 equids (horses and related animals).
  • The equids were of special interest as some had been part of a ranch where a recent neurological disorder outbreak had occurred.

Methods

  • The sera were tested using a plaque-reduction neutralisation test, which measures the ability of an individual’s serum to prevent a virus from forming plaques, or visible structures in cell layers.
  • An animal was considered seropositive if it had a 4-fold or greater difference in antibody titres, which is a measure of how much antibody an organism has produced.

Results

  • Among the 748 equids, 10 (1.3%) were seropositive for the Mayaro virus and two (0.3%) for the Venezuelan equine encephalitis virus (VEEV).
  • Among the 484 equids without a history of immunisation, 48 (9.9%) were seropositive for the Eastern equine encephalitis virus (EEEV) and four (0.8%) for the Western equine encephalitis virus (WEEV).
  • From the sheep population, five were seropositive for equine encephalitis alphaviruses, with specific counts for each virus. Caimans also showed presence of antibodies to VEEV and other, undetermined alphaviruses.
  • However, the research was unable to connect the neurological disorder outbreak on the ranch to any of the alphaviruses under study.

Conclusions

  • The study provides strong evidence that the Mayaro virus, as well as all equine encephalitis alphaviruses tested, had circulated in the Pantanal region.
  • These findings have implications for public health and animal health in the region, as these viruses can be transmitted to humans and may cause diseases.

Cite This Article

APA
Pauvolid-Corrêa A, Juliano RS, Campos Z, Velez J, Nogueira RM, Komar N. (2015). Neutralising antibodies for Mayaro virus in Pantanal, Brazil. Mem Inst Oswaldo Cruz, 110(1), 125-133. https://doi.org/10.1590/0074-02760140383

Publication

Memorias do Instituto Oswaldo Cruz
ISSN: 1678-8060
NlmUniqueID: 7502619
Country: Brazil
Language: English
Volume: 110
Issue: 1
Pages: 125-133
PII: S0074-02762015000100125

Researcher Affiliations

Pauvolid-Corrêa, Alex
  • Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, RJ, Brasil.
Juliano, Raquel Soares
  • Embrapa Pantanal, Ministério da Agricultura Pecuária e Abastecimento, Corumbá, MS, Brasil.
Campos, Zilca
  • Embrapa Pantanal, Ministério da Agricultura Pecuária e Abastecimento, Corumbá, MS, Brasil.
Velez, Jason
  • Centers for Disease Control and Prevention, Fort Collins, CO, USA.
Nogueira, Rita Maria Ribeiro
  • Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, RJ, Brasil.
Komar, Nicholas
  • Centers for Disease Control and Prevention, Fort Collins, CO, USA.

MeSH Terms

  • Age Factors
  • Alligators and Crocodiles / blood
  • Alligators and Crocodiles / immunology
  • Alphavirus / immunology
  • Animals
  • Antibodies, Neutralizing / blood
  • Antibodies, Viral / blood
  • Brazil / epidemiology
  • Encephalitis Virus, Eastern Equine / immunology
  • Encephalitis Virus, Venezuelan Equine / immunology
  • Encephalitis Virus, Western Equine / immunology
  • Encephalomyelitis, Eastern Equine / epidemiology
  • Encephalomyelitis, Eastern Equine / veterinary
  • Encephalomyelitis, Venezuelan Equine / epidemiology
  • Encephalomyelitis, Venezuelan Equine / veterinary
  • Encephalomyelitis, Western Equine / epidemiology
  • Encephalomyelitis, Western Equine / veterinary
  • Horse Diseases / blood
  • Horse Diseases / immunology
  • Horse Diseases / prevention & control
  • Horses / blood
  • Horses / immunology
  • Neutralization Tests
  • Seroepidemiologic Studies
  • Sheep / blood
  • Sheep / immunology
  • Wetlands

References

This article includes 57 references
  1. Aguiar DM, Cavalcante GT, Lara MCCSH, Villalobos EMC, Cunha EMS, Okuda LH, De Stefano E, Nassar AFC, Souza GO, Vasconcellos SA, Labruna MB, Camargo LMA, Gennari SM. Prevalência de anticorpos contra agentes virais e bacterianos em equinos do município de Monte Negro, Rondônia, Amazônia ocidental brasileira.. Braz J Vet Res Anim Sci 2008;45:269–276.
  2. Alho CJR. The Pantanal. In: Fraser LH, Keddy PA, editors. The world's largest wetlands: ecology and conservation. Cambridge University Press; New York: 2005. pp. 203–271.
  3. Alice FJ. Infecção humana pelo vírus leste de encefalite equina. Bol Inst Biol Bahia 1956;3:3–9.
  4. Almeida TI, Calijuri Mdo C, Falco PB, Casali SP, Kupriyanova E, Paranhos Filho AC, Sigolo JB, Bertolo RA. Biogeochemical processes and the diversity of Nhecolândia lakes, Brazil.. An Acad Bras Cienc 2011 Jun;83(2):391-407.
    pubmed: 21670869doi: 10.1590/s0001-37652011000200004google scholar: lookup
  5. Araújo FAA, Andrade MA, Jayme VS, Santos AL, Romano APM, Ramos DG, Cunha EMS, Ferreira MS, Lara MCCSH, Villalobos EMC, Martins LC. Antibodies to alphavirus detected in horses during different epizootics of equine encephalitis, Paraiba state, Brazil, 2009. Rev Bras Parasitol Vet 2012;19:80–85.
  6. Azevedo RS, Silva EV, Carvalho VL, Rodrigues SG, Nunes-Neto JP, Monteiro H, Peixoto VS, Chiang JO, Nunes MR, Vasconcelos PF. Mayaro fever virus, Brazilian Amazon.. Emerg Infect Dis 2009 Nov;15(11):1830-2.
    pmc: PMC2857233pubmed: 19891877doi: 10.3201/eid1511.090461google scholar: lookup
  7. Barber TL, Walton TE, Lewis KJ. Efficacy of trivalent inactivated encephalomyelitis virus vaccine in horses.. Am J Vet Res 1978 Apr;39(4):621-5.
    pubmed: 646197
  8. Batista PM, Andreotti R, Almeida PS, Marques AC, Rodrigues SG, Chiang JO, Vasconcelos PF. Detection of arboviruses of public health interest in free-living New World primates (Sapajus spp.; Alouatta caraya) captured in Mato Grosso do Sul, Brazil.. Rev Soc Bras Med Trop 2013 Nov-Dec;46(6):684-90.
    pubmed: 24474008doi: 10.1590/0037-8682-0181-2013google scholar: lookup
  9. Bauer RW, Gill MS, Poston RP, Kim DY. Naturally occurring eastern equine encephalitis in a Hampshire wether.. J Vet Diagn Invest 2005 May;17(3):281-5.
    pubmed: 15945389doi: 10.1177/104063870501700314google scholar: lookup
  10. Beaty B, Calisher CH, Shope RE, Lennette EH, Lennette DA, Lennette ET. Viral, rickettsial and chlamydial infections. American Public Health Association; Washington DC: 1995. Arboviruses; pp. 189–212.
  11. Bertone JJ. Togaviral encephalitis. In: Reed SM, Bayly WM, editors. Equine internal medicine. WB Saunders; Philadelphia: 1998. pp. 501–510.
  12. Bowen GS. Prolonged western equine encephalitis viremia in the Texas tortoise (Gopherus berlandieri).. Am J Trop Med Hyg 1977 Jan;26(1):171-5.
    pubmed: 842780doi: 10.4269/ajtmh.1977.26.171google scholar: lookup
  13. Brewer BD, Mayhew IG. Clinicopathologic diagnosis of eastern equine encephalomyelitis. Proc ACVIM 1990;8:469–470.
  14. Bruno-Lobo G, Bruno-Lobo M, Travassos J, Pinheiro FF, Pazin IP. Estudos sôbre arbovírus III: isolamento de um vírus sorológicamente relacionado ao sub-grupo Western-Sindbis de um caso de encefalomielite eqüina ocorrido no Rio de Janeiro. Ann Microbiol 1961;9:183–195.
  15. Calisher CH, Emerson JK, Muth DJ, Lazuick JS, Monath TP. Serodiagnosis of western equine encephalitis virus infections: relationships of antibody titer and test to observed onset of clinical illness.. J Am Vet Med Assoc 1983 Aug 15;183(4):438-40.
    pubmed: 6618970
  16. Calisher CH, Shope RE, Brandt W, Casals J, Karabatsos N, Murphy FA, Tesh RB, Wiebe ME. Proposed antigenic classification of registered arboviruses I. Togaviridae, Alphavirus.. Intervirology 1980;14(5-6):229-32.
    pubmed: 6265396doi: 10.1159/000149190google scholar: lookup
  17. Campos KF, de Oliveira CHS, Reis AB, Yamasaki EM, Brito MF, Andrade SJT, Duarte MD, Barbosa JD. Surto de encefalomielite equina leste na Ilha de Marajó, Pará. Pesq Vet Bras 2013;33:443–448.
  18. Carneiro V, Cunha R. Estudos sobre a encefalomielite infecciosa dos equídeos no Brasil. Arq Inst Biol 1943;14:157–194.
  19. Causey OR, Shope RE, Sutmoller P, Laemmert H. Epizootic eastern equine encephalitis in the Bragança region of Pará, Brazil. Rev Serv Esp Saude Publ 1962;12:39–45.
  20. Coimbra TL, Santos CL, Suzuki A, Petrella SM, Bisordi I, Nagamori AH, Marti AT, Santos RN, Fialho DM, Lavigne S, Buzzar MR, Rocco IM. Mayaro virus: imported cases of human infection in São Paulo State, Brazil.. Rev Inst Med Trop Sao Paulo 2007 Jul-Aug;49(4):221-4.
    pubmed: 17823750doi: 10.1590/s0036-46652007000400005google scholar: lookup
  21. Cunha EMS, Villalobos EMC, Nassar AFC, Lara MCCSH, Peres NF, Palazzo JPC, Silva A, De Stefano E, Pino FA. Prevalência de anticorpos contra agentes virais em equídeos no sul do estado de São Paulo. Arq Inst Biol 2009;76:165–171.
  22. Cunha R. Estudos sôbre uma amostra de vírus da encefalomielite equina isolada de material proveniente de Recife. Bol Soc Bras Med Vet 1945;14:201–201.
  23. Dégallier N, da Rosa APAT, Vasconcelos PFC, Sá Filho GC, da Rosa EST, Rodrigues SG, da Rosa JFST. Evolutionary aspects of the ecology of arboviruses in Brazilian Amazonia, South America. In: da Rosa APAT, Vasconcelos PFC, da Rosa JFST, editors. An overview of arbovirology in Brazil and neighbouring countries. Instituto Evandro Chagas; Belém: 1998. pp. 42–60.
  24. Fernández Z, Richartz R, Travassos da Rosa A, Soccol VT. [Identification of the encephalitis equine virus, Parana, Brazil].. Rev Saude Publica 2000 Jun;34(3):232-5.
    pubmed: 10920444doi: 10.1590/s0034-89102000000300004google scholar: lookup
  25. Graham SP, Hassan HK, Chapman T, White G, Guyer C, Unnasch TR. Serosurveillance of eastern equine encephalitis virus in amphibians and reptiles from Alabama, USA.. Am J Trop Med Hyg 2012 Mar;86(3):540-4.
    pmc: PMC3284378pubmed: 22403333doi: 10.4269/ajtmh.2012.11-0283google scholar: lookup
  26. Heinemann MB, Souza MC, Cortez A, Ferreira F, Homem VSF, Ferreira-Neto JS, Soares RM, Cunha EMS, Richtzenhain LJ. Soroprevalência da encefalomielite eqüina do leste e do oeste no Município de Uruará, PA, Brasil. Braz J Vet Res Anim Sci 2006;43:137–139.
  27. IBGE - Instituto Brasileiro de Geografia e Estatística . Sistema IBGE de recuperação automática - SIDRA, Banco de dadosnagregados. 2014. sidra.ibge.gov.br
  28. Iversson LB, da Rosa APAT, Rodrigues SG, Rosa MDB. Human disease caused by Venezuelan equine encephalitis subtype IF in Ribeira Valley, São Paulo, Brazil. 39th Annual Meeting of the American Society of Tropical Medicine and Hygiene   ; 1990 Nov 4-8; New Orleans. ASTMH; 1990. pp. 143–143.
  29. Iversson LB, Silva RA, da Rosa AP, Barros VL. Circulation of eastern equine encephalitis, western equine encephalitis, Ilhéus, Maguari and Tacaiuma viruses in equines of the Brazilian Pantanal, South America.. Rev Inst Med Trop Sao Paulo 1993 Jul-Aug;35(4):355-9.
    pubmed: 8115796doi: 10.1590/s0036-46651993000400009google scholar: lookup
  30. Junk WJ, Cunha CN. Pantanal: a large South American wetland at a crossroads. Ecol Eng 2005;24:391–401.
  31. Karstad L. Reptiles as possible reservoir hosts for eastern encephalitis virus. Proc N Am Wildl Nat Res Conf 1961;26:186–202.
  32. Komar N, Clark GG. West Nile virus activity in Latin America and the Caribbean.. Rev Panam Salud Publica 2006 Feb;19(2):112-7.
    pubmed: 16551385doi: 10.1590/s1020-49892006000200006google scholar: lookup
  33. Lopes IF, Brito RA, Henrique-Silva F, Del Lama FS. Demographic history of wood stork (Mycteria americana) Brazilian Pantanal colonies revealed by mitochondrial DNA analysis. Genet Mol Biol 2006;29:241–250.
  34. Melo RM, Cavalcanti RC, Villalobos EMC, Cunha EMS, Lara MCCSH, Aguiar DM. Ocorrência de equídeos soropositivos para os vírus das encefalomielites e anemia infecciosa no estado de Mato Grosso. Arq Inst Biol 2012;79:169–175.
  35. MMA - Ministério do Meio Ambiente . Biomas: Pantanal. 2014. mma.gov.br/biomas/pantanal
  36. Mourão G, Coutinho M, Mauro R, Campos Z, Tomás W, Magnusson. Aerial surveys of caiman, marsh deer and pampas deer in the Pantanal wetland of Brazil. Biol Conserv 2000;92:175–183.
  37. Mourão MP, Bastos Mde S, de Figueiredo RP, Gimaque JB, Galusso Edos S, Kramer VM, de Oliveira CM, Naveca FG, Figueiredo LT. Mayaro fever in the city of Manaus, Brazil, 2007-2008.. Vector Borne Zoonotic Dis 2012 Jan;12(1):42-6.
    pmc: PMC3249893pubmed: 21923266doi: 10.1089/vbz.2011.0669google scholar: lookup
  38. Navarro JC, Medina G, Vasquez C, Coffey LL, Wang E, Suárez A, Biord H, Salas M, Weaver SC. Postepizootic persistence of Venezuelan equine encephalitis virus, Venezuela.. Emerg Infect Dis 2005 Dec;11(12):1907-15.
    pmc: PMC3367636pubmed: 16485478doi: 10.3201/eid1112.050533google scholar: lookup
  39. Olson GA, Hessler JR, Faith RE. Technics for blood collection and intravascular infusion of reptiles.. Lab Anim Sci 1975 Dec;25(6):783-6.
    pubmed: 1207049
  40. Ostfeld RS, Keesing F. The function of biodiversity in the ecology of vector-borne zoonotic diseases. Can J Zool 2000;78:2061–2078.
  41. . Cases of chikungunya fever in the Americas by country or territoryn2013-2015. 2015.
  42. Pauvolid-Corrêa A, Campos Z, Juliano R, Velez J, Nogueira RM, Komar N. Serological evidence of widespread circulation of West Nile virus and other flaviviruses in equines of the Pantanal, Brazil.. PLoS Negl Trop Dis 2014 Feb;8(2):e2706.
    pmc: PMC3923745pubmed: 24551266doi: 10.1371/journal.pntd.0002706google scholar: lookup
  43. Pauvolid-Corrêa A, Kenney JL, Couto-Lima D, Campos ZM, Schatzmayr HG, Nogueira RM, Brault AC, Komar N. Ilheus virus isolation in the Pantanal, west-central Brazil.. PLoS Negl Trop Dis 2013;7(7):e2318.
    pmc: PMC3715421pubmed: 23875051doi: 10.1371/journal.pntd.0002318google scholar: lookup
  44. Pauvolid-Corrêa A, Morales MA, Levis S, Figueiredo LT, Couto-Lima D, Campos Z, Nogueira MF, da Silva EE, Nogueira RM, Schatzmayr HG. Neutralising antibodies for West Nile virus in horses from Brazilian Pantanal.. Mem Inst Oswaldo Cruz 2011 Jun;106(4):467-74.
    pubmed: 21739036doi: 10.1590/s0074-02762011000400014google scholar: lookup
  45. Pauvolid-Corrêa A, Tavares FN, Alencar J, Silva Jdos S, Murta M, Serra-Freire NM, Pellegrin AO, Gil-Santana H, Guimarães AE, Silva EE. Preliminary investigation of Culicidae species in South Pantanal, Brazil and their potential importance in arbovirus transmission.. Rev Inst Med Trop Sao Paulo 2010 Jan-Feb;52(1):17-24.
    pubmed: 20305950doi: 10.1590/s0036-46652010000100003google scholar: lookup
  46. Pauvolid-Corrêa A, Tavares FN, Costa EV, Burlandy FM, Murta M, Pellegrin AO, Nogueira MF, Silva EE. Serologic evidence of the recent circulation of Saint Louis encephalitis virus and high prevalence of equine encephalitis viruses in horses in the Nhecolândia sub-region in South Pantanal, Central-West Brazil.. Mem Inst Oswaldo Cruz 2010 Sep;105(6):829-33.
    pubmed: 20945001doi: 10.1590/s0074-02762010000600017google scholar: lookup
  47. Pinheiro FP, da Rosa APAT, Freitas RB, da Rosa JFST, Vasconcelos PFC. Instituto Evandro Chagas, 50 anos de contribuição às ciências biológicas e à medicina tropical. Vol. 1. Fundação SESP; Belém: 1986. Arboviroses. Aspectos clinico-epidemiológicos; pp. 375–408.
  48. PORTERFIELD JS. Cross-neutralization studies with group A arthropod-borne viruses.. Bull World Health Organ 1961;24(6):735-41.
    pmc: PMC2555518pubmed: 13737288
  49. Silva JV, Abdon MM. Delimitação do Pantanal brasileiro e suas sub-regiões. Pesq Agropec Bras 1988;33:1703–1711.
  50. Silva ML, Galiza GJ, Dantas AF, Oliveira RN, Iamamoto K, Achkar SM, Riet-Correa F. Outbreaks of Eastern equine encephalitis in northeastern Brazil.. J Vet Diagn Invest 2011 May;23(3):570-5.
    pubmed: 21908293doi: 10.1177/1040638711403414google scholar: lookup
  51. Straube FC, Urben-Filho A, Nunes AP, Tomás WM, Vieira-da-Rocha MC. Avifauna do Pantanal de Nabileque (Mato Grosso do Sul, Brasil) Atualidades Ornitológicas. 2006;134:1–22.
  52. Vasconcelos PFC, da Rosa APAT, Pinheiro FP, Shope RE, da Rosa JFST, Rodrigues SG, Dégallier N, da Rosa EST. An overview of arbovirology in Brazil and neighbouring countries. Instituto Evandro Chagas; Belém: 1998. Arboviruses pathogenic for man in Brasil; pp. 72–9:9.
  53. Viana LA, Soares P, Paiva F, Lourenço-De-Oliveira R. Caiman-biting mosquitoes and the natural vectors of Hepatozoon caimani in Brazil.. J Med Entomol 2010 Jul;47(4):670-6.
    pubmed: 20695284doi: 10.1603/me09260google scholar: lookup
  54. Walder R, Suarez OM, Calisher CH. Arbovirus studies in the Guajira region of Venezuela: activities of eastern equine encephalitis and Venezuelan equine encephalitis viruses during an interepizootic period.. Am J Trop Med Hyg 1984 Jul;33(4):699-707.
    pubmed: 6148023doi: 10.4269/ajtmh.1984.33.699google scholar: lookup
  55. Waldridge BM, Wenzel JG, Ellis AC, Rowe-Morton SE, Bridges ER, D'Andrea G, Wint R. Serologic responses to eastern and western equine encephalomyelitis vaccination in previously vaccinated horses.. Vet Ther 2003 Fall;4(3):242-8.
    pubmed: 15136985
  56. Walton TE, Jochim MM, Barber TL, Thompson LH. Cross-protective immunity between equine encephalomyelitis viruses in equids.. Am J Vet Res 1989 Sep;50(9):1442-6.
    pubmed: 2552875
  57. Zuchi N, Heinen LB, Santos MA, Pereira FC, Slhessarenko RD. Molecular detection of Mayaro virus during a dengue outbreak in the state of Mato Grosso, Central-West Brazil.. Mem Inst Oswaldo Cruz 2014 Sep;109(6):820-3.
    pmc: PMC4238776pubmed: 25141284doi: 10.1590/0074-0276140108google scholar: lookup

Citations

This article has been cited 22 times.
  1. Krokovsky L, Lins CRB, Guedes DRD, Wallau GDL, Ayres CFJ, Paiva MHS. Dynamic of Mayaro Virus Transmission in Aedes aegypti, Culex quinquefasciatus Mosquitoes, and a Mice Model.. Viruses 2023 Mar 21;15(3).
    doi: 10.3390/v15030799pubmed: 36992508google scholar: lookup
  2. García-Romero C, Carrillo Bilbao GA, Navarro JC, Martin-Solano S, Saegerman C. Arboviruses in Mammals in the Neotropics: A Systematic Review to Strengthen Epidemiological Monitoring Strategies and Conservation Medicine.. Viruses 2023 Feb 1;15(2).
    doi: 10.3390/v15020417pubmed: 36851630google scholar: lookup
  3. Dias HG, de Lima RC, Barbosa LS, Souza TMA, Badolato-Correa J, Maia LMS, Ferreira RDS, Neves NADS, Costa MCS, Martins LR, Souza EM, Carvalho MDS, Araujo-Oliveira A, Marques WA, Sabino-Santos G, Marques MS, Macedo GC, Nantes WAG, Santos FM, Netto CC, Morgado TO, Bianchini MA, Correa SHR, Almeida JR, Campos LP, Souza IM, Barreto WTG, Porfírio G, Alencar JAF, Herrera HM, Shlessarenko RD, Cunha RVD, Azeredo EL, Salyer SJ, Komar N, Pauvolid-Corrêa A, Dos Santos FB. Retrospective molecular investigation of Mayaro and Oropouche viruses at the human-animal interface in West-central Brazil, 2016-2018.. PLoS One 2022;17(11):e0277612.
    doi: 10.1371/journal.pone.0277612pubmed: 36395285google scholar: lookup
  4. Chalhoub FLL, Horta MAP, Alcantara LCJ, Morales A, Dos Santos LMB, Guerra-Campos V, Rodrigues CDS, Santos CC, Mares-Guia MAM, Pauvolid-Corrêa A, de Filippis AMB. Serological Evidence of Exposure to Saint Louis Encephalitis and West Nile Viruses in Horses of Rio de Janeiro, Brazil.. Viruses 2022 Nov 6;14(11).
    doi: 10.3390/v14112459pubmed: 36366557google scholar: lookup
  5. Dos Santos Souza Marinho R, Duro RLS, Bellini Caldeira D, Galinskas J, Oliveira Mota MT, Hunter J, Rodrigues Teles MDA, de Pádua Milagres FA, Sobhie Diaz R, Shinji Kawakubo F, Vasconcelos Komninakis S. Re-emergence of mayaro virus and coinfection with chikungunya during an outbreak in the state of Tocantins/Brazil.. BMC Res Notes 2022 Aug 3;15(1):271.
    doi: 10.1186/s13104-022-06153-6pubmed: 35922804google scholar: lookup
  6. Nunes JDSDSS, Casseb LMN, Guimarães RJPS, Reis WDM, de Barros BCV, Ferreira MS, Chiang JO, Pinheiro HHC, Vasconcelos PFDC, Cruz ACR. Serological evidence of Eastern equine encephalitis circulation in equids in Pará state, Brazil.. Braz J Vet Med 2021;43:e001720.
    doi: 10.29374/2527-2179.bjvm001720pubmed: 35749099google scholar: lookup
  7. Dias HG, Dos Santos FB, Pauvolid-Corrêa A. An Overview of Neglected Orthobunyaviruses in Brazil.. Viruses 2022 May 7;14(5).
    doi: 10.3390/v14050987pubmed: 35632729google scholar: lookup
  8. Ortiz DI, Piche-Ovares M, Romero-Vega LM, Wagman J, Troyo A. The Impact of Deforestation, Urbanization, and Changing Land Use Patterns on the Ecology of Mosquito and Tick-Borne Diseases in Central America.. Insects 2021 Dec 23;13(1).
    doi: 10.3390/insects13010020pubmed: 35055864google scholar: lookup
  9. Celone M, Okech B, Han BA, Forshey BM, Anyamba A, Dunford J, Rutherford G, Mita-Mendoza NK, Estallo EL, Khouri R, de Siqueira IC, Pollett S. A systematic review and meta-analysis of the potential non-human animal reservoirs and arthropod vectors of the Mayaro virus.. PLoS Negl Trop Dis 2021 Dec;15(12):e0010016.
    doi: 10.1371/journal.pntd.0010016pubmed: 34898602google scholar: lookup
  10. Caicedo EY, Charniga K, Rueda A, Dorigatti I, Mendez Y, Hamlet A, Carrera JP, Cucunubá ZM. The epidemiology of Mayaro virus in the Americas: A systematic review and key parameter estimates for outbreak modelling.. PLoS Negl Trop Dis 2021 Jun;15(6):e0009418.
    doi: 10.1371/journal.pntd.0009418pubmed: 34081717google scholar: lookup
  11. Björnström A, Blomström AL, Singh MC, Hesson JC. Sindbis virus neutralising antibodies detected in Swedish horses.. One Health 2021 Jun;12:100242.
    doi: 10.1016/j.onehlt.2021.100242pubmed: 33851003google scholar: lookup
  12. Diagne CT, Bengue M, Choumet V, Hamel R, Pompon J, Missé D. Mayaro Virus Pathogenesis and Transmission Mechanisms.. Pathogens 2020 Sep 8;9(9).
    doi: 10.3390/pathogens9090738pubmed: 32911824google scholar: lookup
  13. Julia da Silva Pessoa Vieira C, José Ferreira da Silva D, Rigotti Kubiszeski J, Ceschini Machado L, Pena LJ, Vieira de Morais Bronzoni R, da Luz Wallau G. The Emergence of Chikungunya ECSA Lineage in a Mayaro Endemic Region on the Southern Border of the Amazon Forest.. Trop Med Infect Dis 2020 Jun 26;5(2).
    doi: 10.3390/tropicalmed5020105pubmed: 32604785google scholar: lookup
  14. Mota MTO, Costa VV, Sugimoto MA, Guimarães GF, Queiroz-Junior CM, Moreira TP, de Sousa CD, Santos FM, Queiroz VF, Passos I, Hubner J, Souza DG, Weaver SC, Teixeira MM, Nogueira ML. In-depth characterization of a novel live-attenuated Mayaro virus vaccine candidate using an immunocompetent mouse model of Mayaro disease.. Sci Rep 2020 Mar 24;10(1):5306.
    doi: 10.1038/s41598-020-62084-xpubmed: 32210270google scholar: lookup
  15. Ganjian N, Riviere-Cinnamond A. Mayaro virus in Latin America and the Caribbean.. Rev Panam Salud Publica 2020;44:e14.
    doi: 10.26633/RPSP.2020.14pubmed: 32051685google scholar: lookup
  16. Barba M, Fairbanks EL, Daly JM. Equine viral encephalitis: prevalence, impact, and management strategies.. Vet Med (Auckl) 2019;10:99-110.
    doi: 10.2147/VMRR.S168227pubmed: 31497528google scholar: lookup
  17. Naveca FG, Claro I, Giovanetti M, de Jesus JG, Xavier J, Iani FCM, do Nascimento VA, de Souza VC, Silveira PP, Lourenço J, Santillana M, Kraemer MUG, Quick J, Hill SC, Thézé J, Carvalho RDO, Azevedo V, Salles FCDS, Nunes MRT, Lemos PDS, Candido DDS, Pereira GC, Oliveira MAA, Meneses CAR, Maito RM, Cunha CRSB, Campos DPS, Castilho MDC, Siqueira TCDS, Terra TM, de Albuquerque CFC, da Cruz LN, Abreu AL, Martins DV, Simoes DSMV, Aguiar RS, Luz SLB, Loman N, Pybus OG, Sabino EC, Okumoto O, Alcantara LCJ, Faria NR. Genomic, epidemiological and digital surveillance of Chikungunya virus in the Brazilian Amazon.. PLoS Negl Trop Dis 2019 Mar;13(3):e0007065.
    doi: 10.1371/journal.pntd.0007065pubmed: 30845267google scholar: lookup
  18. Kantor AM, Lin J, Wang A, Thompson DC, Franz AWE. Infection Pattern of Mayaro Virus in Aedes aegypti (Diptera: Culicidae) and Transmission Potential of the Virus in Mixed Infections With Chikungunya Virus.. J Med Entomol 2019 Apr 16;56(3):832-843.
    doi: 10.1093/jme/tjy241pubmed: 30668762google scholar: lookup
  19. Tambo E, Khayeka-Wandabwa C, Olalubi OA, Adedeji AA, Ngogang JY, Khater EI. Addressing knowledge gaps in molecular, sero-surveillance and monitoring approaches on Zika epidemics and other arbovirus co-infections: A structured review.. Parasite Epidemiol Control 2017 May;2(2):50-60.
    doi: 10.1016/j.parepi.2017.01.001pubmed: 29774281google scholar: lookup
  20. Pauvolid-Corrêa A, Campos Z, Soares R, Nogueira RMR, Komar N. Neutralizing antibodies for orthobunyaviruses in Pantanal, Brazil.. PLoS Negl Trop Dis 2017 Nov;11(11):e0006014.
    doi: 10.1371/journal.pntd.0006014pubmed: 29091706google scholar: lookup
  21. Brunini S, França DDS, Silva JB, Silva LN, Silva FPA, Spadoni M, Rezza G. High Frequency of Mayaro Virus IgM among Febrile Patients, Central Brazil.. Emerg Infect Dis 2017 Jun;23(6):1025-1026.
    doi: 10.3201/eid2306.160929pubmed: 28518022google scholar: lookup
  22. Pauvolid-Corrêa A, Solberg O, Couto-Lima D, Nogueira RM, Langevin S, Komar N. Novel Viruses Isolated from Mosquitoes in Pantanal, Brazil.. Genome Announc 2016 Nov 3;4(6).
    doi: 10.1128/genomeA.01195-16pubmed: 27811095google scholar: lookup
Subscribe to our newsletter
Join 99,357 horse owners like you who receive our email updates on horse health and nutrition.