[New drugs for horses and production animals in 2023].

The research summarizes pharmaceutical developments in 2023 for horses and production animals in Germany. No new active pharmaceutical ingredients were introduced, but existing medications were approved for additional species and medication adjustments were made for smaller animals.

Existing Drugs Approved for Additional Species

• Butafosfan, a phosphorus compound, received clearance for use in horses, dogs, and cats. Originally, the usage of this drug might have been restricted to other animal species.
• A mineral, sodium chloride in an isotonic solution, was also approved for rabbits and guinea pigs. Previously, this isotonic sodium solution might not have been permitted for use in these smaller animals.

Modifications for Small Animal Drugs

• A new form of Pergolidmesilate, a drug with a reduced active ingredient content, was released. It must have been important to lower the content of the active ingredient to make it more appropriate for smaller animals.
• Fluralaner was also released in a smaller packaging size. Likely, this adjustment was made to better suit the dosage requirements of smaller animals.
• Lastly, a new method of administering Oxalic Acid Dihydrate was introduced. This could have been an alternative route of administration that is more favorable or convenient in certain situations or for specific animals.

Re-Introduction of Drug Combinations

• The article also mentions that a combination of active ingredients – Diprophylline and Heptaminol – was re-introduced to the market for horses and food-producing animals. The pharmaceutical industry often ceases production of certain drug combinations due to various factors such as demand, cost-effectiveness, and efficacy. However, they might be brought back as needed or when these constraints are addressed.