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Home / Equine Research Bank / Equine Vet J / Noninvasive diode laser-an effective and safe treatment of i...
Equine veterinary journal2022; 55(2); 205-213; doi: 10.1111/evj.13590

Noninvasive diode laser-an effective and safe treatment of iris cysts in 46 eyes of 35 horses.

Abstract: Iris cysts in horses are often asymptomatic and noticed incidentally. However, cysts can cause local corneal oedema and erratic behaviour like shying, decreased performance and head-shaking. Objective: To describe the use of diode laser as a noninvasive treatment option for iris cysts in the horse and to document factors influencing its efficacy, associated complications, long-term outcome and rate of recurrence. Methods: Retrospective case series. Methods: Case records of horses treated for iris cysts by diode laser at the Utrecht University Equine Clinic were reviewed between 2008 and 2020. Diagnosis was based on ophthalmic and ultrasonographic evaluation. Long-term follow-up was obtained in two phases, a telephone survey with the owner and a photographic re-evaluation of the treated eyes. Results: Thirty-five horses were included, with a total of 46 eyes treated. One day after diode laser treatment (short-term), 35/46 treated eyes had a good decrease in cyst size, 7/46 had a moderate effect, 1/46 had a minimal effect, 1/46 had no effect, and in two cases the effect was unspecified. The decrease in size after diode laser treatment in polycystic eyes (odds ratio [OR] 0.381, 95% CI 0.1530-0.724), p = 0.001), thick-walled cysts (OR = 0.139; CI = 0.023-0.726, p = 0.02) and hyperplastic corpora nigra (OR = 0.081; CI = 0.004-0.528, p = 0.03) was significantly less satisfactory, with ORs of 0.381, 0.139 and 0.081, respectively. Minor complications, such as mild reactive uveitis, were reported in 8/46 (17%) eyes. On long-term follow-up (median 19 months; IQR 25.5), clinical signs had diminished or disappeared in most cases (93%) and 83% of the owners would recommend the treatment. Based on long-term photographic re-evaluation (median 32.5 months; IQR 49.75), 2/16 cases of recurrence were seen. Conclusions: Retrospective design, follow-up by telephone questionnaire and photographic re-evaluation. Loss to follow-up in the photographic re-evaluation. Conclusions: Both short- and long-term results indicate diode laser treatment is a useful and safe option for iris cyst size reduction, with a low risk of recurrence. Presurgical ultrasonography is recommended to assess the feasibility of treatment and to allow for better surgical planning. 背景:马虹膜囊肿通常是无症状，偶然发现的。然而，囊肿可引起局部角膜水肿以及马匹不稳定的行为，如害羞、表现下降和甩/摇头等。 目的:描述使用半导体激光作为马虹膜囊肿的非侵入性治疗方案，并记录影响其疗效、相关并发症、长期结果和复发率的因素。 研究设计:回顾性病例系列研究 方法:回顾了2008年至2020年在乌特勒支大学马诊所使用二极管激光治疗马虹膜囊肿的病例记录。诊断基于眼科和超声检查进行评估。长期随访分两个阶段进行，一是与患者电话调查，二是对被治疗的眼睛进行照片重新评估。 结果:记录的35匹马，共治疗46只眼睛。在经过二极管激光治疗后1天(短期)显示，35例(35/46)囊肿明显减小，7例效果中等，1例效果轻微，1例无效果，2例效果不明。经二极管激光治疗后，囊肿缩小数据显示，有多囊性眼(OR= 0.381；CI =0.153-0.724，p= 0.001)、厚壁性眼(OR = 0.139；CI = 0.023 - 0.726, p =0.02)和增殖性黑体(OR = 0.081; CI = 0.004 - 0.528, p=0.03)的患马，效果不佳，优势比OR分别为0.381、0.139和0.081。记录中另有8只眼有轻微并发症，如轻度反应性葡萄膜炎(8/46,17%)。长期随访(中位数19个月；IQR 25.5)，绝大多数临床症状减轻或消失(93%)；83%的马主会建议治疗。根据眼部照片进行长期再评价(中位数32.5个月；IQR 49.75)，有 2例(2/16)复发。 主要局限性:本研究属于回顾性质，通过电话问卷和摄影照片进行重新评估。基于照片的重估失去了一些随访数据。 结论:短期和长期结果表明，二极管激光治疗马虹膜囊肿是一种有效和安全的选择，复发风险低。建议术前超声检查以评估治疗的可行性，并制定更好的手术计划.
© 2022 The Authors. Equine Veterinary Journal published by John Wiley & Sons Ltd on behalf of EVJ Ltd.
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Publication Date: 2022-07-11 PubMed ID: 35575001PubMed Central: PMC10083948DOI: 10.1111/evj.13590Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the effectiveness of noninvasive diode laser treatment on iris cysts in horses, showing it significantly reduces cyst size with minimal complications and low risk of recurrence.

Objective of the Study

  • The study aimed to document the application and effectiveness of diode laser as a noninvasive treatment for iris cysts in horses. The research also sought to examine factors influencing the treatment’s efficacy, associated complications, long-term outcome, and the rate of recurrence.

Research Method

  • This study took a retrospective design where case records of horses treated for iris cysts by diode laser at the Utrecht University Equine Clinic were reviewed spanning the years 2008 to 2020.
  • The diagnosis of the cysts was based on ophthalmic and ultrasonographic evaluation.
  • A two-phase long-term follow-up was conducted. The first phase involved a telephone survey with the horse owners, while the second stage included a photographic re-evaluation of the treated eyes.

Research Results

  • The study covered 35 horses, with 46 eyes treated. One day after diode laser treatment (short-term), the cyst size had a good decrease in 35/46 treated eyes, a moderate effect in 7/46, a minimal effect in 1/46 and no effect in 1/46. Two cases remained unspecified.
  • The results following the diode laser treatment were less satisfactory for polycystic eyes, thick-walled cysts and eyes with hyperplastic corpora nigra.
  • Minor complications were reported in eight eyes (17%) most of which was mild reactive uveitis.
  • Long-term follow-up results showed a diminished or fully disappeared symptoms in 93% of cases, with 83% of the owners recommending the treatment.
  • From the long-term photographic re-evaluation, recurrence was seen in 2 out of 16 cases.

Conclusions of the Study

  • Both short- and long-term results indicate diode laser treatment is a valuable and safe option for reducing iris cyst size in horses, with low risk of recurrence.
  • Presurgical ultrasonography is recommended to assess the feasibility of the treatment and to generate a more accurate surgical planning.

Limitations of the Study

  • The study was retrospective thus may not comprehensively capture all the factors that could influence the outcome.
  • Loss of some data in the follow-up process, specifically in the photographic re-evaluation, could also be a shortcoming.

Cite This Article

APA
Stas EKL, Hermans H, Slenter IJM, Veraa S, Ensink JM. (2022). Noninvasive diode laser-an effective and safe treatment of iris cysts in 46 eyes of 35 horses. Equine Vet J, 55(2), 205-213. https://doi.org/10.1111/evj.13590

Publication

Equine veterinary journal
ISSN: 2042-3306
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 55
Issue: 2
Pages: 205-213

Researcher Affiliations

Stas, Emanuël K L
  • Faculty of Veterinary Medicine, Department Clinical Sciences, Equine Sciences, Equine Surgery and Orthopaedics, Utrecht University, CM, Utrecht, The Netherlands.
Hermans, Hanneke
  • Faculty of Veterinary Medicine, Department Clinical Sciences, Equine Sciences, Equine Surgery and Orthopaedics, Utrecht University, CM, Utrecht, The Netherlands.
Slenter, Inge J M
  • Faculty of Veterinary Medicine, Department Clinical Sciences, Surgery of Companion Animals, Ophthalmology, CM, Utrecht, The Netherlands.
Veraa, Stefanie
  • Faculty of Veterinary Medicine, Department Clinical Sciences, Diagnostic Imaging, Utrecht University, CM, Utrecht, The Netherlands.
Ensink, Jos M
  • Faculty of Veterinary Medicine, Department Clinical Sciences, Equine Sciences, Equine Surgery and Orthopaedics, Utrecht University, CM, Utrecht, The Netherlands.

MeSH Terms

  • Horses
  • Animals
  • Lasers, Semiconductor / therapeutic use
  • Retrospective Studies
  • Iris / surgery
  • Cornea
  • Cysts / veterinary
  • Cysts / surgery
  • Treatment Outcome
  • Horse Diseases / surgery

Grant Funding

  • Utrecht University

Conflict of Interest Statement

No competing interests have been declared.

References

This article includes 27 references
  1. Andersson LS, Axelsson J, Dubielzig RR, Lindgren G, Ekesten B. Multiple congenital ocular anomalies in Icelandic horses.. BMC Vet Res 2011 May 26;7:21.
    pmc: PMC3125316pubmed: 21615885doi: 10.1186/1746-6148-7-21google scholar: lookup
  2. Gemensky-Metzler AJ, Wilkie DA, Cook CS. The use of semiconductor diode laser for deflation and coagulation of anterior uveal cysts in dogs, cats and horses: a report of 20 cases.. Vet Ophthalmol 2004 Sep-Oct;7(5):360-8.
    pubmed: 15310297doi: 10.1111/j.1463-5224.2004.04004.xgoogle scholar: lookup
  3. Hurn SD, Turner AG. Ophthalmic examination findings of Thoroughbred racehorses in Australia.. Vet Ophthalmol 2006 Mar-Apr;9(2):95-100.
    pubmed: 16497233doi: 10.1111/j.1463-5224.2006.00444.xgoogle scholar: lookup
  4. Paschalis-Trela K, Cywińska A, Trela J, Czopowicz M, Kita J, Witkowski L. The prevalence of ocular diseases in polish Arabian horses.. BMC Vet Res 2017 Nov 7;13(1):319.
    pmc: PMC5678559pubmed: 29115950doi: 10.1186/s12917-017-1252-8google scholar: lookup
  5. Ramsey DT, Ewart SL, Render JA, Cook CS, Latimer CA. Congenital ocular abnormalities of Rocky Mountain Horses.. Vet Ophthalmol 1999;2(1):47-59.
    pubmed: 11397242doi: 10.1046/j.1463-5224.1999.00050.xgoogle scholar: lookup
  6. Barnett KC, Crispin SM, Lavach JD, Matthews AG. Color atlas and text of equine ophthalmology. 2nd ed. London, England: Elsevier Inc; 2004. p. 184–91.
  7. Gilger BC. Equine ophthalmology. 3rd ed., John Wiley & Sons Inc; 2016;374–5.
  8. Crispin SM. Developmental anomalies and abnormalities of the equine iris.. Vet Ophthalmol 2000;3(2-3):93-98.
    pubmed: 11397289doi: 10.1046/j.1463-5224.2000.00113.xgoogle scholar: lookup
  9. Brooks DE. Corpora nigra/iris cysts in the horse. Equine Vet. Educ. 2007;19:512–4.
  10. Byam‐Cook KL, Knottenbelt DC. Recurrent corneal ulceration secondary to an iris cyst. Equine Vet Educ. 2007;19:508–11.
  11. Carastro SM. Equine ocular anatomy and ophthalmic examination.. Vet Clin North Am Equine Pract 2004 Aug;20(2):285-99.
    pubmed: 15271424doi: 10.1016/j.cveq.2004.04.013google scholar: lookup
  12. Gilger BC, Davidson MG, Nadelstein B, Nasisse M. Neodymium:yttrium-aluminum-garnet laser treatment of cystic granula iridica in horses: eight cases (1988-1996).. J Am Vet Med Assoc 1997 Aug 1;211(3):341-3.
    pubmed: 9262677
  13. Deehr AJ, Dubielzig RR. A histopathological study of iridociliary cysts and glaucoma in Golden Retrievers.. Vet Ophthalmol 1998;1(2-3):153-158.
    pubmed: 11397224doi: 10.1046/j.1463-5224.1998.00018.xgoogle scholar: lookup
  14. Barnett KC, Platt H. Intraocular melanomata in the horse.. Equine Vet J Suppl 1990 Sep;(10):76-82.
    pubmed: 9079124doi: 10.1111/j.2042-3306.1990.tb04718.xgoogle scholar: lookup
  15. Myrna K, Sheridan C. Melanocytic ocular and periocular tumours of the horse. Equine Vet. Educ. 2019;31:410–2.
  16. Scotty NC, Barrie KB, Brooks DE, Taylor D. Surgical management of a progressive iris melanocytoma in a Mustang.. Vet Ophthalmol 2008 Mar-Apr;11(2):75-80.
    pubmed: 18302571doi: 10.1111/j.1463-5224.2008.00603.xgoogle scholar: lookup
  17. Sidoti PA, Valencia M, Chen N, Baerveldt G, Green RL. Echographic evaluation of primary cysts of the iris pigment epithelium.. Am J Ophthalmol 1995 Aug;120(2):161-7.
    pubmed: 7639299doi: 10.1016/s0002-9394(14)72603-0google scholar: lookup
  18. Toth J, Buijs L. Erfahrungen mit der Therapie vin Iriszysten mittels Laserzystotomie und Reduktion von vergrösserten Traubenkörnern beim Pferd mit einem Nd:YAG‐Laser. Prakt Tierarzt 2018;99:1276–85.
  19. Blacklock BT, Grundon RA, Meehan M, Tetas Pont R, Hartley C. Uveal cysts in domestic cats: a retrospective evaluation of thirty-six cases.. Vet Ophthalmol 2016 Jul;19 Suppl 1:56-60.
    pubmed: 26778521doi: 10.1111/vop.12345google scholar: lookup
  20. Gialletti R, Marchegiani A, Valeriani T, Nannarone S, Beccati F, Fruganti A, Laus F. A survey of ocular ultrasound abnormalities in horse: 145 cases.. J Ultrasound 2018 Mar;21(1):53-59.
    pmc: PMC5845941pubmed: 29492841doi: 10.1007/s40477-018-0284-7google scholar: lookup
  21. Berger JM, Bell SA, Holmberg BJ, Madigan JE. Successful treatment of head shaking by use of infrared diode laser deflation and coagulation of corpora nigra cysts and behavioral modification in a horse.. J Am Vet Med Assoc 2008 Nov 15;233(10):1610-2.
    pubmed: 19014298doi: 10.2460/javma.233.10.1610google scholar: lookup
  22. Georgalas I, Petrou P, Papaconstantinou D, Brouzas D, Koutsandrea C, Kanakis M. Iris cysts: A comprehensive review on diagnosis and treatment.. Surv Ophthalmol 2018 May-Jun;63(3):347-364.
    pubmed: 28882598doi: 10.1016/j.survophthal.2017.08.009google scholar: lookup
  23. Gywat L, Keller M, Gutzwiller A, Daicker B, Brückner R. [Surgical removal of a cyst from the iris of a horse].. Schweiz Arch Tierheilkd 1988 Dec;130(12):673-80.
    pubmed: 3212435
  24. Mustikka MP, Pietilä EM, Mykkänen AK, Grönthal TSC. Comparison of two rebound tonometers in healthy horses.. Vet Ophthalmol 2020 Sep;23(5):892-898.
    pmc: PMC7540552pubmed: 32888242doi: 10.1111/vop.12819google scholar: lookup
  25. Knollinger AM, La Croix NC, Barrett PM, Miller PE. Evaluation of a rebound tonometer for measuring intraocular pressure in dogs and horses.. J Am Vet Med Assoc 2005 Jul 15;227(2):244-8.
    pubmed: 16047660doi: 10.2460/javma.2005.227.244google scholar: lookup
  26. Pumphrey SA, Pizzirani S, Pirie CG, Needle DB. Glaucoma associated with uveal cysts and goniodysgenesis in American Bulldogs: a case series.. Vet Ophthalmol 2013 Sep;16(5):377-85.
    pubmed: 23110479doi: 10.1111/vop.12000google scholar: lookup
  27. Rao A, Gupta V, Bhadange Y, Sharma R, Shields JA. Iris cysts: a review.. Semin Ophthalmol 2011 Jan;26(1):11-22.
    pubmed: 21275599doi: 10.3109/08820538.2010.541319google scholar: lookup

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