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MMWR. Morbidity and mortality weekly report2016; 65(30); 788; doi: 10.15585/mmwr.mm6530a5

Notes from the Field: Fatal Infection Associated with Equine Exposure – King County, Washington, 2016.

Abstract: On March 17, 2016, Public Health-Seattle & King County in Washington was notified of two persons who received a diagnosis of Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) infections. S. zooepidemicus is a zoonotic pathogen that rarely causes human illness and is usually associated with consuming unpasteurized dairy products or with direct horse contact (1). In horses, S. zooepidemicus is a commensal bacterium that can cause respiratory, wound, and uterine infections (2). The health department investigated to determine the magnitude of the outbreak, identify risk factors, and offer recommendations.
Publication Date: 2016-08-05 PubMed ID: 27490189DOI: 10.15585/mmwr.mm6530a5Google Scholar: Lookup
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Summary

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The research article discusses a fatal infection linked with exposure to horses that occurred in King County, Washington, in 2016. The infections were caused by a zoonotic bacterium, Streptococcus equi subspecies zooepidemicus (S. zooepidemicus), typically found in horses and rarely in humans.

About the Streptococcus equi subspecies zooepidemicus

  • The Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) is a type of bacterium that is typically found in horses but can occasionally infect humans. It is transmitted through consuming unpasteurized dairy products or through direct contact with horses.
  • In horses, this bacterium is commonly present but can occasionally cause respiratory, wound, and uterine infections.
  • Although rare, human infection by S. zooepidemicus can result in serious or even fatal outcomes.

The 2016 King County Cases

  • On March 17, 2016, Public Health-Seattle & King County was alerted about two persons diagnosed with S. zooepidemicus infections.
  • This precipitated an investigation by the health department to assess the spread of the outbreak, identify the risk factors, andprovide recommendations.

Significance and Implications

  • This study signals that S. zooepidemicus, although a rare causative agent of human illness, still poses a significant risk, especially for people who have close contact with horses or consume unpasteurized dairy products.
  • The health department’s response and investigation highlights the importance of quick action and in-depth research in understanding and managing infectious disease outbreaks.

Research Recommendations

  • This research calls for increased vigilance and precautionary measures for those in close contact with horses or those consuming unpasteurized dairy products to limit the spread of S. zooepidemicus in humans.
  • Further investigations should be made on the behavior and pathogenicity of S. zooepidemicus to allow for improved prevention and treatment strategies.

Cite This Article

APA
Kawakami V, Rietberg K, Lipton B, Eckmann K, Watkins M, Oltean H, Kay M, Rothschild C, Kobayashi M, Van Beneden C, Duchin J. (2016). Notes from the Field: Fatal Infection Associated with Equine Exposure – King County, Washington, 2016. MMWR Morb Mortal Wkly Rep, 65(30), 788. https://doi.org/10.15585/mmwr.mm6530a5

Publication

ISSN: 1545-861X
NlmUniqueID: 7802429
Country: United States
Language: English
Volume: 65
Issue: 30
Pages: 788

Researcher Affiliations

Kawakami, Vance
    Rietberg, Krista
      Lipton, Beth
        Eckmann, Kaye
          Watkins, Maryann
            Oltean, Hanna
              Kay, Meagan
                Rothschild, Chantal
                  Kobayashi, Miwako
                    Van Beneden, Chris
                      Duchin, Jeff

                        MeSH Terms

                        • Adult
                        • Aged
                        • Animal Husbandry
                        • Animals
                        • Fatal Outcome
                        • Female
                        • Horse Diseases / diagnosis
                        • Horse Diseases / microbiology
                        • Horse Diseases / transmission
                        • Horses
                        • Humans
                        • Streptococcal Infections / diagnosis
                        • Streptococcal Infections / microbiology
                        • Streptococcal Infections / transmission
                        • Streptococcal Infections / veterinary
                        • Streptococcus equi / isolation & purification
                        • Washington
                        • Zoonoses

                        Citations

                        This article has been cited 3 times.
                        1. Nocera FP, D'Eletto E, Ambrosio M, Fiorito F, Pagnini U, De Martino L. Occurrence and Antimicrobial Susceptibility Profiles of Streptococcus equi subsp. zooepidemicus Strains Isolated from Mares with Fertility Problems. Antibiotics (Basel) 2021 Dec 27;11(1).
                          doi: 10.3390/antibiotics11010025pubmed: 35052902google scholar: lookup
                        2. Sack A, Oladunni FS, Gonchigoo B, Chambers TM, Gray GC. Zoonotic Diseases from Horses: A Systematic Review. Vector Borne Zoonotic Dis 2020 Jul;20(7):484-495.
                          doi: 10.1089/vbz.2019.2541pubmed: 32077811google scholar: lookup
                        3. Torres RSLA, Santos TZ, Bernardes AFL, Soares PA, Soares ACC, Dias RS. Outbreak of Glomerulonephritis Caused by Streptococcus zooepidemicus SzPHV5 Type in Monte Santo de Minas, Minas Gerais, Brazil. J Clin Microbiol 2018 Oct;56(10).
                          doi: 10.1128/JCM.00845-18pubmed: 30068536google scholar: lookup