Nuclear scintigraphic assessment of the thoracolumbar synovial intervertebral articulations.
Abstract: The results of nuclear scintigraphic examination of the thoracolumbar synovial intervertebral articulations (facet joints) have to date been poorly documented. Objective: To establish an objective scintigraphic grading system for the facet joints; to investigate the relationship between the presence or absence of clinical signs of back pain and increased radiopharmaceutical uptake (IRU); and to compare the results of scintigraphy and radiography. Methods: Nuclear scintigraphic images of the 13th thoracic (T13) to first lumbar (L1) vertebrae were graded subjectively (visual assessment of the image) and objectively (using region of interest analysis) from 31 clinically normal horses in full work (Group N) and 65 horses with clinical evidence of thoracolumbar region pain and osteoarthritis of > or = 1 facet joint (Group B). Sensitivity and specificity of IRU for detection of back pain and radiographic abnormalities were assessed. A Spearman correlation was performed to test for an association between the grade of IRU and the classification of radiographic abnormality. Results: The objective scintigraphic grades were matched by 96.7% of subjective grades. IRU was seen more commonly in Group B (61.5%) than in Group N (25.8%), and moderate or intense IRU was only seen in Group B. The strongest association between radiographic abnormalities and scintigraphy was seen in horses with intense IRU. Conclusions: Moderate or intense IRU in a facet joint is more likely to be seen in horses with back pain than in clinically normal horses. Conclusions: Nuclear scintigraphy is a potentially useful tool in the evaluation of a horse with thoracolumbar region pain.
Publication Date: 2009-10-07 PubMed ID: 19803047DOI: 10.2746/042516409x376940Google Scholar: Lookup
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- Journal Article
Summary
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This research article focuses on establishing an objective grading system for facet joints in horses using nuclear scintigraphy and examines the correlation between pain symptoms, radiopharmaceutical uptake (IRU), and radiographic results. The ultimate aim is to better understand and assess back pain in horses, particularly in the thoracolumbar region.
Methods and Participants
- The researchers used nuclear scintigraphy – which allows for the imaging of bodily functions through detection of radiopharmaceuticals – to study the thoracolumbar synovial intervertebral articulations (or facet joints) in horses. These images were then graded both subjectively and objectively.
- The test subjects were composed of two groups: Group N, with 31 clinically normal horses in full work, and Group B, with 65 horses displaying clinical evidence of thoracolumbar region pain and osteoarthritis.
- The investigators also compared the results from the scintigraphy assessment with traditional radiography to better analyze and validate their findings.
Results and Findings
- The results showed a high level of agreement (96.7%) between the subjective and objective grades from the nuclear scintigraphy, suggesting a successful establishment of the objective scintigraphic grading system.
- Increased radiopharmaceutical uptake – a potential sign of inflammation or disease – was more common in Group B (61.5%) than in Group N (25.8%). Furthermore, moderate or intense IRU was only seen in Group B, inconsistent with the clinically normal horses in Group N.
- A strong association was found between radiographic abnormalities and scintigraphy results for horses in Group B, indicating that the IRU could be a significant indicator of disease or discomfort.
Conclusion
- The researchers concluded that moderate or intense cases of increased radiopharmaceutical uptake are more likely found in horses experiencing back pain than in clinically normal horses.
- The study supports the use of nuclear scintigraphy as a potentially effective tool in evaluating and diagnosing thoracolumbar region pain in horses.
Cite This Article
APA
Gillen A, Dyson S, Murray R.
(2009).
Nuclear scintigraphic assessment of the thoracolumbar synovial intervertebral articulations.
Equine Vet J, 41(6), 534-540.
https://doi.org/10.2746/042516409x376940 Publication
Researcher Affiliations
- Centre for Equine Studies, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK.
MeSH Terms
- Animals
- Horse Diseases / diagnosis
- Horse Diseases / diagnostic imaging
- Horse Diseases / pathology
- Horses
- Joint Diseases / diagnosis
- Joint Diseases / pathology
- Joint Diseases / veterinary
- Lumbar Vertebrae / diagnostic imaging
- Radiography
- Radionuclide Imaging / veterinary
- Sensitivity and Specificity
- Spinal Diseases / diagnosis
- Spinal Diseases / diagnostic imaging
- Spinal Diseases / veterinary
- Synovial Membrane / diagnostic imaging
- Synovial Membrane / pathology
- Thoracic Vertebrae / diagnostic imaging
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