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Equine veterinary journal2004; 36(5); 390-396; doi: 10.2746/0425164044868369

Nutritional and clinicopathological effects of post operative parenteral nutrition following small intestinal resection and anastomosis in the mature horse.

Abstract: There is an absence of data describing the nutritional requirements and nutritional status of horses following surgery for colic; furthermore, the potential effect of parenteral nutrition (PN) on improving nutritional status in such cases is unknown. Objective: Post operative colic cases suffer from a potentially detrimental negative energy balance and the PN formulation developed in this study would lead to clinicopathologically detectable improvements in the subjects' nutritional status. Methods: Several clinicopathological variables, some known to be associated with nutritional status, were compared in 2 groups of horses in the post operative period following colic surgery; Group N (n = 15) were treated with PN and Group C (n = 15) were starved routinely. Results: Group N had significantly lower serum concentrations of triglycerides, total bilirubin, albumin and urea and significantly higher serum concentrations of glucose and insulin compared with Group C in the post operative period. Conclusions: The control group of horses demonstrated significant clinicopathological evidence of starvation and the described PN protocol resulted in a demonstrably improved nutritional status in the treated horses. Conclusions: Further study is required to investigate clinical benefits and possible harmful side effects of post operative parenteral nutrition before the technique can be advocated for widespread use in practice.
Publication Date: 2004-07-16 PubMed ID: 15253078DOI: 10.2746/0425164044868369Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

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The research article investigates the impact of post-surgery parental nutrition (PN) treatment on horses that have undergone colic surgery, by examining various clinical variables and comparing two groups – one that received PN and another that was starved routinely. The findings report an improved nutritional status in horses treated with PN, while also noting the need for further investigations before recommending PN for a wider application in practice.

Objective of the Research

  • The main purpose of the study was to fill a knowledge gap concerning the nutritional needs and status of horses after undergoing surgery for colic. The potential effects of parenteral nutrition (PN, i.e., feeding a person or animal intravenously, bypassing the usual process of eating and digestion) in such scenarios had not been adequately addressed before.
  • The researchers hypothesized that post-operative colic cases could experience harmful energy deficits and that the use of PN could prove beneficial in improving the nutritional status of these horses.

Methodology of the Research

  • The study involved separating horses into two groups after they had had colic surgery. Group N (comprising 15 horses) were administered PN, while Group C (also comprising 15 horses) were routinely starved.
  • Various clinicopathological variables that are generally associated with nutritional status were examined and compared between the two groups in the post-operative period.

Findings of the Research

  • The researchers found that Group N (those treated with PN) had significantly lower serum concentrations of triglycerides, total bilirubin, albumin, and urea compared to Group C (those that were starved). Conversely, Group N had higher serum concentrations of glucose and insulin in the post-operative period.
  • The control group (Group C), showed significant clinicopathological evidence of starvation. On the other hand, the PN protocol implemented for Group N resulted in observable improvements in their nutritional status.

Conclusions Drawn

  • The researchers concluded that, based on the observed clinicopathological indications, PN offers appreciable improvements in the nutritional condition of horses post colic surgery.
  • However, before PN can be advocated for widespread use in the general practice, further investigations are required to determine its potential clinical benefits fully and to uncover any potentially harmful side effects associated with its application.

Cite This Article

APA
Durham AE, Phillips TJ, Walmsley JP, Newton JR. (2004). Nutritional and clinicopathological effects of post operative parenteral nutrition following small intestinal resection and anastomosis in the mature horse. Equine Vet J, 36(5), 390-396. https://doi.org/10.2746/0425164044868369

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 36
Issue: 5
Pages: 390-396

Researcher Affiliations

Durham, A E
  • The Liphook Equine Hospital, Forest Mere, Liphook, Hampshire GU30 7JG, UK.
Phillips, T J
    Walmsley, J P
      Newton, J R

        MeSH Terms

        • Anastomosis, Surgical / veterinary
        • Animals
        • Colic / surgery
        • Colic / therapy
        • Colic / veterinary
        • Female
        • Horse Diseases / surgery
        • Horse Diseases / therapy
        • Horses
        • Intestine, Small / surgery
        • Male
        • Nutritional Requirements
        • Nutritional Status
        • Parenteral Nutrition
        • Postoperative Care / methods
        • Postoperative Care / veterinary
        • Time Factors
        • Treatment Outcome

        Citations

        This article has been cited 4 times.
        1. Filippo PAD, Duarte BR, Albernaz AP, Quirino CR. Effects of feed deprivation on physical and blood parameters of horses. Braz J Vet Med 2021;43:e000321.
          doi: 10.29374/2527-2179.bjvm000321pubmed: 35749104google scholar: lookup
        2. Lawson AL, Sherlock CE, Ireland JL, Mair TS. Equine nutrition in the post-operative colic: Survey of Diplomates of the American Colleges of Veterinary Internal Medicine and Veterinary Surgeons, and European Colleges of Equine Internal Medicine and Veterinary Surgeons. Equine Vet J 2021 Sep;53(5):1015-1024.
          doi: 10.1111/evj.13381pubmed: 33174212google scholar: lookup
        3. Edner AH, Nyman GC, Essén-Gustavsson B. Metabolism before, during and after anaesthesia in colic and healthy horses. Acta Vet Scand 2007 Nov 15;49(1):34.
          doi: 10.1186/1751-0147-49-34pubmed: 18001483google scholar: lookup
        4. Cruz AM, Coté N, McDonell WN, Geor RJ, Wilson BA, Monteith G, Li R. Postoperative effects of anesthesia and surgery on resting energy expenditure in horses as measured by indirect calorimetry. Can J Vet Res 2006 Oct;70(4):257-62.
          pubmed: 17042377