Nutritional aspects of post exercise skeletal muscle glycogen synthesis in horses: a comparative review.
Abstract: Carbohydrate (CHO) stored in the form of skeletal muscle glycogen is the main energy source for glycolytic and oxidative ATP production during vigorous exercise in mammals. In man, horse and dog both short-term high intensity and prolonged submaximal exercise deplete muscle glycogen. In horses, however, muscle glycogen synthesis is 2-3-fold slower than in man and rat, even when a diet high in soluble CHO is fed. There appear to be significant differences in CHO and glycogen metabolism between horses and other mammals, and it is becoming increasingly clear that many conclusions drawn from human exercise physiology do not apply to horses. This review aims to provide a comprehensive, comparative summary of the research on muscle glycogen synthesis in horse, man and rodent. Species differences in CHO uptake and utilisation are examined and the issues with feeding high soluble CHO diets to horses are discussed. Alternative feeding strategies, including protein and long and short chain fatty acid supplementation and the importance of rehydration, are explored.
Publication Date: 2010-05-22 PubMed ID: 20486986DOI: 10.2746/042516409X479603Google Scholar: Lookup
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- Journal Article
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Summary
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The research article provides a comparative analysis of muscle glycogen synthesis (the process through which the body creates and stores energy) following exercise in horses, humans, and rodents. The study suggests that glycogen synthesis in horses is significantly slower compared to humans and rats, despite a diet high in carbohydrates.
Understanding Muscle Glycogen Synthesis
- The research focuses on muscle glycogen synthesis, which is the process of creating glycogen, a form of energy storage, in the muscles.
- It notes that carbohydrate stored as muscle glycogen is the main source of energy for intense and prolonged exercise in mammals such as humans, horses, and dogs.
- The body uses this glycogen stored in the muscles for ATP (adenosine triphosphate) production, which fuels cellular activities and hence physical exercise.
Carbohydrate Utilisation and Glycogen Synthesis in Horses
- The study has found that in horses, muscle glycogen synthesis is 2-3 times slower than in humans and rats, even when the diet is rich in soluble carbohydrates.
- The researchers highlight that there seem to be significant differences in the metabolism of carbohydrates and glycogen in horses compared to other mammals.
- The data suggests that many conclusions derived from human exercise physiology studies may not be applicable to horses due to these differences.
Exploring Feeding Strategies and Dietary Implications
- The article provides a comprehensive summary of research on muscle glycogen synthesis in horses, humans, and rodents, highlighting the potential species differences in carbohydrate absorption and use.
- The study delves into the issues related to feeding horses with a high soluble carbohydrate diet, indicating potential drawbacks or inefficiencies in this approach.
- It suggests exploring alternative feeding strategies for horses, including supplementation with protein, long-chain and short-chain fatty acids,
- Besides, the importance of rehydration is also stressed, underlining that replenishing fluids is critical for optimal recovery and replenishment of glycogen stores post-exercise.
Cite This Article
APA
Waller AP, Lindinger MI.
(2010).
Nutritional aspects of post exercise skeletal muscle glycogen synthesis in horses: a comparative review.
Equine Vet J, 42(3), 274-281.
https://doi.org/10.2746/042516409X479603 Publication
Researcher Affiliations
- Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, N1G 2W1, Canada.
MeSH Terms
- Animal Nutritional Physiological Phenomena
- Animals
- Dietary Carbohydrates
- Glycogen / biosynthesis
- Horses / metabolism
- Muscle, Skeletal / physiology
- Physical Conditioning, Animal / physiology
Citations
This article has been cited 10 times.- Vidal Moreno de Vega C, Lemmens D, de Meeûs d'Argenteuil C, Boshuizen B, de Maré L, Leybaert L, Goethals K, de Oliveira JE, Hosotani G, Deforce D, Van Nieuwerburgh F, Devisscher L, Delesalle C. Dynamics of training and acute exercise-induced shifts in muscular glucose transporter (GLUT) 4, 8, and 12 expression in locomotion versus posture muscles in healthy horses.. Front Physiol 2023;14:1256217.
- Verdegaal EJMM, Howarth GS, McWhorter TJ, Boshuizen B, Franklin SH, Vidal Moreno de Vega C, Jonas SE, Folwell LE, Delesalle CJG. Continuous Monitoring of the Thermoregulatory Response in Endurance Horses and Trotter Horses During Field Exercise: Baselining for Future Hot Weather Studies.. Front Physiol 2021;12:708737.
- de Meeûs d'Argenteuil C, Boshuizen B, Oosterlinck M, van de Winkel D, De Spiegelaere W, de Bruijn CM, Goethals K, Vanderperren K, Delesalle CJG. Flexibility of equine bioenergetics and muscle plasticity in response to different types of training: An integrative approach, questioning existing paradigms.. PLoS One 2021;16(4):e0249922.
- Tabozzi SA, Stancari G, Zucca E, Tajoli M, Stucchi L, Lafortuna CL, Ferrucci F. Variation of skeletal muscle ultrasound imaging intensity in horses after treadmill exercise: a proof of concept for glycogen content estimation.. BMC Vet Res 2021 Mar 16;17(1):121.
- Klein DJ, McKeever KH, Mirek ET, Anthony TG. Metabolomic Response of Equine Skeletal Muscle to Acute Fatiguing Exercise and Training.. Front Physiol 2020;11:110.
- Szcześniak KA, Ciecierska A, Ostaszewski P, Sadkowski T. Characterisation of equine satellite cell transcriptomic profile response to β-hydroxy-β-methylbutyrate (HMB).. Br J Nutr 2016 Oct;116(8):1315-1325.
- Le Moyec L, Robert C, Triba MN, Billat VL, Mata X, Schibler L, Barrey E. Protein catabolism and high lipid metabolism associated with long-distance exercise are revealed by plasma NMR metabolomics in endurance horses.. PLoS One 2014;9(3):e90730.
- Corkey BE, Shirihai O. Metabolic master regulators: sharing information among multiple systems.. Trends Endocrinol Metab 2012 Dec;23(12):594-601.
- Williams CL, Sato K, Shiomi K, Ponganis PJ. Muscle energy stores and stroke rates of emperor penguins: implications for muscle metabolism and dive performance.. Physiol Biochem Zool 2012 Mar-Apr;85(2):120-33.
- El-Deeb WM, El-Bahr SM. Investigation of selected biochemical indicators of Equine Rhabdomyolysis in Arabian horses: pro-inflammatory cytokines and oxidative stress markers.. Vet Res Commun 2010 Dec;34(8):677-89.
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