Oestrogens in faeces as an indicator of the foeto-placental unit function in mares.

The research article discusses an experiment carried out on 30 pregnant horses, examining the concentration of oestrogens in faecal samples as an indicator of the function of the foeto-placental unit, both in regular pregnancies and those that were interrupted or ended in abortion.

Research Methodology

• The subject of study were 30 pregnant mares, out of which 17 were Thoroughbred and 13 were Primitive Polish Horse.
• The study was conducted by determining the concentration of total unconjugated oestrogens, a class of steroidal hormones, in faecal samples of these mares. The samples were obtained every second week after mating until delivery or interruption of pregnancy.
• Oestrogen concentrations were measured using a technique called radioimmunoassay, a scientifically accurate method used to measure the concentration of specific proteins or hormones.

Findings of the Study

• The concentration of oestrogens in healthy pregnant mares varied between 40 and 200 ng/g and indicated typical pregnancy profiles.
• Abortions and cases of embryonic death were reported in 5 out of 30 mares, representing 16.6% of the total population, regardless of their breed.
• Concerning those who experienced abortions, a sharp or gradual decrease in oestrogen concentration was observed prior to the incident.
• On the other hand, there was no noted elevation of hormone levels prior to cases of embryonic death.

Conclusion of the Study

• Based on the research data, it is suggested that determining the level of faecal oestrogens could act as an indicator of the functioning of the foeto-placental unit. This could be applicable for both physiological (normal) and pathological (abnormal or diseased) pregnancies.
• The study implies that monitoring the faecal oestrogen levels might help detect pregnancy abnormalities or risks of abortion in mares.