On-site testing of sutured organs: An experimental set up to cyclically tighten sutures.

This research focuses on developing and testing an experimental device designed to examine the performance of suture prostheses. The device aims to reveal any problems with suture loosening or wear that may occur over time due to repeated loading cycles, using an equine laryngoplasty as a benchmark for testing.

Objective of the Study

• The primary goal of the study was to develop an experimental device to perform ex vivo tests on prosthetic sutures. This was carried out to understand how successful the sutures are over a middle-long term period after the surgery. A secondary aim was to identify any possible improvements in surgical techniques, specifically in relation to how the suture is anchored to the cartilage.

Methodology

• The researchers used an equine laryngoplasty as a benchmark to represent sutures aimed at compensating for weakened or atrophied muscles.
• The device was used to apply over 3000 load cycles, repeatedly tightening the suture under known loads.
• The study also included a tensile test up to rupture to assess the strength and durability of the suture.
• Force/displacement curves were used to classify the biomechanical performance of sutures over time, focusing on its creep behavior.

Findings

• The results showed that the organ-suture system undergoes significant creep over 3000 cycles. This indicates that the long-term performance of the suture is likely to decrease over time with repeated loading cycles.
• The researchers also found that the way the suture is anchored to the cartilage should be improved to ensure the longevity and effectiveness of the procedure.

Implications

• The experimental device can be used for on-site testing of sutures in terms of compliance and creep response at both suture anchorage ends. This can help in comparing different surgeries and different kinds of threads to identify the best practices.
• Overall, this study contributes significantly to the field of surgical practices, especially those involving the use of sutures, as it offers an effective way to anticipate future complications and improve the success rate of surgeries.